203 research outputs found
Women, Islam and Cinema
Gönül Dönmez-Colin's book, Women, Islam and Cinema, comes not a day too soon. At a time when controversies rage over the wearing of the veil in school, reality seems to be catching up with fiction. Dönmez-Colin speaks of the insidious and conservative ways in which cinema in many Islamic countries has portrayed women. Her sweep is large: she covers India, Pakistan, Bangladesh, Malaysia, Indonesia, Iran, Turkey, Kazakhstan and Uzbekistan and draws careful analogies and contradictions that exist within and among these countries. Inevitably, cinema's depiction of women as actresses, directors and spectators grows out of the prevailing social and political atmosphere: stifling patriarchy and female subordination...
Cinemas of the Other
Cinemas of the Other: A personal journey with film-makers from the Middle East and Central Asia. Cinemas of the Other is a film buff's delight. This set of extended, thoroughly researched interviews with twenty-seven renowned filmmakers from seven countries is accompanied by a pithy and useful biographical note on each one of her interviewees - just enough to give you a glimpse of their personality but never too long to give anything away. That something personal emerges from the lengthy interviews...
Modeling and analysis of hospital facility layout problem
The optimal solution to any facility layout problem is an important aspect and a major concem as it involves significant material handling and transportation cost. The objective is to arrange the departments within the predefined facility boundaries in the way that the interaction between the functions is efficient and the overall movement cost is minimized. While facility layout problems have traditionally focused on manufacturing facilities, there has been little work on analyzing layouts for hospitals. The thesis focuses on hospital facility layout problems (HLP) to (i) minimize the movements of patients and (ii) minimize the movements of accompanying resources such as doctors, nurses, equipment and paramedical staff. The thesis consists of two sections. In the first section, a model for the multi-floor layout problem is presented based on the minimization of movement cost. The model has travel frequency or number of trips, trip difficulty rating, baseline travel cost and distance as parameters for determining the movement cost. In the second section, some additional parameters and constraints are imposed on the model and it is simulated using Microsoft Excel. Simulations are also run to study the effect of different proposed strategies on movement cost. These proposed strategies show a reduction in movement cost from the sample layout strategy in section one. A representative example is used to illustrate the applicability of the proposed formulation
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A Tablet-Based Assessment of Rhythmic Ability.
The exponential rise in use of mobile consumer electronics has presented a great potential for research to be conducted remotely, with participants numbering several orders of magnitude greater than a typical research paradigm. Here, we attempt to demonstrate the validity and reliability of using a consumer game-engine to create software presented on a mobile tablet to assess sensorimotor synchronization, a proxy of rhythmic ability. Our goal was to ascertain whether previously observed research results can be replicated, rather than assess whether a mobile tablet achieves comparable performance to a desktop computer. To achieve this, younger (aged 18-35 years) and older (aged 60-80 years) adult musicians and non-musicians were recruited to play a custom-designed sensorimotor synchronization assessment on a mobile tablet in a controlled laboratory environment. To assess reliability, participants performed the assessment twice, separated by a week, and an intra-class correlation coefficient (ICC) was calculated. Results supported the validity of this approach to assessing rhythmic abilities by replicating previously observed results. Specifically, musicians performed better than non-musicians, and younger adults performed better than older adults. Participants also performed best when the tempo was in the range of previously-identified preferred tempos, when the stimuli included both audio and visual information, and when synchronizing on-beat compared to off-beat or continuation (self-paced) synchronization. Additionally, high ICC values (>0.75) suggested excellent test-retest reliability. Together, these results support the notion that consumer electronics running software built with a game engine may serve as a valuable resource for remote, mobile-based data collection of rhythmic abilities
Phosphate mediated regulation of carbohydrate metabolism in Neurospora crassa
Phosphate mediated regulation of carbohydrate metabolism in Neurospora crass
Angular Rate Estimation Using a Distributed Set of Accelerometers
A distributed set of accelerometers based on the minimum number of 12 accelerometers allows for computation of the magnitude of angular rate without using the integration operation. However, it is not easy to extract the magnitude of angular rate in the presence of the accelerometer noises, and even worse, it is difficult to determine the direction of a rotation because the angular rate is present in its quadratic form within the inertial measurement system equations. In this paper, an extended Kalman filter scheme to correctly estimate both the direction and magnitude of the angular rate through fusion of the angular acceleration and quadratic form of the angular rate is proposed. We also provide observability analysis for the general distributed accelerometers-based inertial measurement unit, and show that the angular rate can be correctly estimated by general nonlinear state estimators such as an extended Kalman filter, except under certain extreme conditions
A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells
Low energy excited state vibrations revealed in conjugated copolymer PCDTBT
Low energy vibrations in the excited state have been hypothesized to play an important role in quickly and efficiently generating free charges in bulk heterojunctions of some conjugated polymer systems. While time-resolved vibrational spectroscopies seemingly are well poised to address the relationship between kinetics and vibrational motions after initial photoexcitation, uncertainty in the measurement arises due to overlapping signals and difficulties in assigning observed oscillatory signals to the molecular response. Here, we demonstrate a high sensitivity strategy to distinguish between signal oscillations originating from lab noise and those molecular in origin in order to isolate the low energy excited-state vibrations in the model conjugated copolymer PCDTBT. Furthermore, to distinguish modes that may be implicated in different kinetic pathways, coherent signal oscillations extracted from 2-dimensional electronic spectroscopy (2DES) are compared for the polymer in two solvents with different polarities resulting in different kinetics. We observe that the change in solvent affects dynamics on the >2 ps scale but not on the time scale required for free charge generation in heterojunctions (similar to 200 fs time scale). By the same token, the excited state vibrational modes that appear and disappear based on solvent polarity may also be associated with the slower kinetic process. The observation of low energy vibrational motions coupled to the excited state manifold that persists through the solvent change and thus can be associated with the fast kinetic process supports the hypothesis that direct polaron formation, rather than exciton formation and diffusion followed by interfacial charge separation, is a more likely route toward free charges in organic heterostructures. Published under license by AIP Publishing
Improving Practice Accessibility Through MyChart Utilization
Aims for Improvement Increase patient portal MyChart activation for a cohort of approximately 2,000 patients at JFMA by 1% from February to April 2021. Demonstrate evidence of utilization including appointment scheduling, results review, and communication with providers through MyChart after activation
Coordinated Activation of the Origin Licensing Factor CDC6 and CDK2 in Resting Human Fibroblasts Expressing SV40 Small T Antigen and Cyclin E
We have previously shown that SV40 small t antigen (st) cooperates with deregulated cyclin E to activate CDK2 and bypass quiescence in normal human fibroblasts (NHF). Here we show that st expression in serum-starved and density-arrested NHF specifically induces up-regulation and loading of CDC6 onto chromatin. Coexpression of cyclin E results in further accumulation of CDC6 onto chromatin concomitantly with phosphorylation of CDK2 on Thr-160 and CDC6 on Ser-54. Investigation of the mechanism leading to CDC6 accumulation and chromatin loading indicates that st is a potent inducer of cdc6 mRNA expression and increases CDC6 protein stability. We also show that CDC6 expression in quiescent NHF efficiently promotes cyclin E loading onto chromatin, but it is not sufficient to activate CDK2. Moreover, we show that CDC6 expression is linked to phosphorylation of the activating T loop of CDK2 in serum-starved NHF stimulated with mitogens or ectopically expressing cyclin E and st. Our data suggest a model where the combination of st and deregulated cyclin E result in cooperative and coordinated activation of both an essential origin licensing factor, CDC6, and an activity required for origin firing, CDK2, resulting in progression from quiescence to S phase
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