Estimation of genetic parameters and selection of Coffea canephora progenies evaluated in Brazilian Western Amazon.

Coffee has emerged as an economic alternative culture in the State of Acre, Brazil, but without a clonal variety recommended for the state to overcome the unevenness presented by seed crops. Thus, in order to estimate genetic parameters and indicate progenies of Coffea canephora to compose a clonal variety for the State of Acre, yield, vegetative vigor and plant height were evaluated in five harvests of a randomized complete block experiment with 46 progenies, 4 repetitions and 10 plants per plot by mixed model methodology (REML/BLUP). The harvests were evaluated individually, by the model that considers one harvest, one location and the mean of progenies, and joint analysis (all harvests), by repeatability model with stability and temporal adaptability by the harmonic mean of relative performance of genotypic values method (MHPRVG), with genotypic values of progenies grouped by the Tocher method. There was variability, with possibility of selection, only for grain yield. The yield was strongly affected by production bienniality, with high environmental influence and harvests mean ranging from 14.13±4.60 to 46.20±14.94 bags ha-1 and individual heritabilities from 0.10 to 0.44. Sixteen ?Conilon? coffee progenies with selection gains above 23% were selected. The MHPRVG method allows the refinement of progeny selection throughout the harvests, identifying the most adapted and stable

A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation

The mammalian nuclear lamina protein lamin B1 is posttranslationally modified by farnesylation, endoproteolysis, and carboxymethylation at a carboxyl-terminal CAAX motif. In this work, we demonstrate that the CAAX endoprotease Rce1 is required for lamin B1 endoproteolysis, demonstrate an independent pool of proteolyzed but nonmethylated lamin B1, as well as fully processed lamin B1, in interphase nuclei, and show a role for methylation in the organization of lamin B1 into domains of the nuclear lamina. Deficiency in the endoproteolysis or methylation of lamin B1 results in loss of integrity and deformity of the nuclear lamina. These data show that the organization of the nuclear envelope and lamina is dependent on a mechanism involving the methylation of lamin B1, and they identify a potential mechanism of laminopathy involving a B-type lamin

Coeficientes técnicos e avaliação econômica para o sistema de produção melhorado da pupunha para palmito no Acre.

A pupunha (Bactris gasipaes Kunth) é uma palmeira que apresenta várias alternativas de utilização: fruto cozido para consumo humano, fabricação de ração, farinha, óleo e palmito, sendo este último, o principal responsável pela expansão da área cultivada com a cultura no Acre (1 .004 ha), podendo a atividade tornar-se uma oportunidade de negócio para pequenos e médios produtores. O cultivo da pupunha para produção de palmito torna-se promissor devido à sua precocidade, rusticidade e elevado perfilhamento, além de permitir melhor controle da qualidade do produto final, quando comparado com o palmito de açaí (Euterpe oleracea) proveniente da exploração extrativa. Ressalta-se ainda o apelo ecológico de seu cultivo, uma vez que contribui para diminuir a pressão dessa atividade predatória. Pretende-se com este trabalho propor um sistema para produção de palmito que contemple as tecnologias de fácil assimilação pelos produtores e que sejam recomendadas pela pesquisa, relacionando as necessidades de materiais, equipamentos e serviços, passíveis de ser utilizados pelos pequenos produtores do Acre.bitstream/item/116573/1/12186.pd

Padrões de controle de crises em pacientes com epilepsia de lobo temporal com ou sem esclerose hipocampal

Objective Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. Method We evaluated 172 patients with MTLE-HS (122) or MTLE-NL (50). Relapse-remitting pattern was defined as periods longer than two years of seizure-freedom intercalated with seizure recurrence. Infrequent seizures was considered as up to three seizures per year and frequent seizures as any period of seizures higher than that. Results Thirty-seven (30%) MTLE-HS and 18 (36%) MTLE-NL patients had relapse-remitting pattern (X2, p = 0.470). This was more common in those with infrequent seizures (X2, p < 0.001). Twelve MTLE-HS and one MTLE-NL patients had prolonged seizure remission between the first and second decade of life (X2, p = 0.06). Conclusion Similar proportion of MTLE-HS or MTLE-NL patients present relapse-remitting seizures and this occurs more often in those with infrequent seizures.Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. Method: We evaluated 172 pat7327982FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO2005/56578-4; 2009/54552-9SEM INFORMAÇÃOPacientes com epilepsia do lobo temporal mesial (ELTM) podem apresentar padrão instável de crises epilépticas. Nosso objetivo foi avaliar ocorrência de crises remitente-recorrentes em ELTM com (ELTM-EH) e sem (ELTM-NL) esclerose hipocampal. Método: Ava

Programa de melhoramento genético de pupunha na Embrapa, IAC e INPA.

Estado da arte; Recursos genéticos; Estratégias de melhoramento; Desenvolvimento experimental.bitstream/item/30975/1/Doc205.pd

Estimating the Heritability of Experiencing Child Maltreatment in an Extended Family Design

Child-driven genetic factors can contribute to negative parenting and may increase the risk of being maltreated. Experiencing childhood maltreatment may be partly heritable, but results of twin studies are mixed. In the current study, we used a cross-sectional extended family design to estimate genetic and environmental effects on experiencing child maltreatment. The sample consisted of 395 individuals (225 women; M age = 38.85 years, rangeage = 7–88 years) from 63 families with two or three participating generations. Participants were oversampled for experienced maltreatment. Self-reported experienced child maltreatment was measured using a questionnaire assessing physical and emotional abuse, and physical and emotional neglect. All maltreatment phenotypes were partly heritable with percentages for h 2 ranging from 30% (SE = 13%) for neglect to 62% (SE = 19%) for severe physical abuse. Common environmental effects (c 2) explained a statistically significant proportion of variance for all phenotypes except for the experience of severe physical abuse (c 2 = 9%, SE = 13%, p = .26). The genetic correlation between abuse and neglect was ρg = .73 (p = .02). Common environmental variance increased as socioeconomic status (SES) decreased (p = .05), but additive genetic and unique environmental variances were constant across different levels of SES

Condições agroclimáticas para subsidiar cultivos do café canéfora no Acre.

Neste capítulo são apresentadas informações sobre condições agroclimáticas, especialmente quanto à distribuição de chuvas e à variação de temperatura do ar que interferem diretamente no desenvolvimento do cafeeiro, voltadas à elaboração do zoneamento do café Canéfora para o cultivo no Estado do Acre

Condições agroclimáticas para subsidiar cultivos do café canéfora no Acre.

Neste capítulo são apresentadas informações sobre condições agroclimáticas, especialmente quanto à distribuição de chuvas e à variação de temperatura do ar que interferem diretamente no desenvolvimento do cafeeiro, voltadas à elaboração do zoneamento do café Canéfora para o cultivo no Estado do Acre