Influencia de la actividad física y los hábitos nutricionales sobre el perfil lipídico, presión arterial e IMC en sujetos con síndrome metabólico

Journal Article;BACKGROUND The present study was determined the influence of physical activity and dietary habits on lipid profile, blood pressure (BP) and body mass index (BMI) in subjects with metabolic syndrome (MS). AIMS Identify the relationship between physical activity and proper nutrition and the probability of suffering from myocardial infarction (MI). METHODS Hundred chronically ill with MS who were active and followed a healthy diet were classified as compliant, while the remaining subjects were classified as non-compliant. RESULTS The compliant subjects show lower BMI values (30.8±4.9 vs 32.5±4.6), as well as lower levels of triacylglycerol (130.4±48.2 vs 242.1±90.1), total cholesterol (193.5±39 vs 220.2±52.3) and low-density lipoprotein cholesterol (105.2±38.3 vs 139.2±45). They show higher values in terms of high-density lipoprotein cholesterol levels (62.2±20.1 vs 36.6±15.3), with statistically significant differences. In terms of both systolic and diastolic pressure, no differences were revealed between the groups; however, those who maintain proper dietary habits show lower systolic blood pressure levels than the inactive subjects. The probability of suffering from MI greatly increases among the group of non-compliant subjects. CONCLUSIONS Our results demonstrate how performing aerobic physical activity and following an individualized, Mediterranean diet significantly reduces MS indicators and the chances of suffering from MI.YesIntroducción:_ En el presente estudio se determinó la influencia de la actividad física y los hábitos nutricionales sobre el perfil lipídico, presión arterial (PA) e índice de masa corporal (IMC) en sujetos con SM. Objetivos: Comprobar la relación entre realizar actividad física y una nutrición adecuada, y la posibilidad de sufrir infarto de miocardio (IM). Método: Se evaluaron 100 sujetos con SM. Los sujetos que manifestaban ser activos y llevaban una alimentación saludable fueron clasificados como cumplidores, mientras que al resto se les clasificó como no cumplidores. Resultados: Los sujetos cumplidores presentan valores menores en cuanto a su IMC (30,8+4,9 vs 32,5+ 4,6) y sus niveles de triglicéridos (130,4+48,2 vs 242,1+90,1) colesterol total (193,5+39 vs 220,2+52,3) y colesterol unido a lipoproteínas de baja densidad (105,2+38,3 vs 139,2+15,3) siendo las diferencias estadísticamente significativas. La PA, tanto sistólica como diastólica, no muestra diferencias entre ambos grupos; en cambio el grupo que manifiesta realizar una alimentación adecuada obtiene unos niveles de presión arterial sistólica menores que el grupo que no la realiza. La posibilidad de padecer IM aumenta significativamente en el grupo de sujetos no cumplidores. Conclusiones: Nuestros resultados muestran como la realización de actividad física de tipo aeróbica y llevar a cabo una alimentación individualizada de tipo mediterráneo reduce significativamente los parámetros relacionados con el SM y las posibilidades de sufrir IM

Extra virgin olive oil diet intervention improves insulin resistance and islet performance in diet-induced diabetes in mice

13 Páginas.-- 7 Figuras.-- 1 TablaDietary composition plays an important role in the pathophysiology of type 2 diabetes. Monounsaturated fatty acid consumption has been positively associated with improved insulin sensitivity and β-cell function. We examined whether an extra virgin olive oil (EVOO) high fat diet (HFD) can improve glucose homeostasis. C57BL/6J mice were fed a standard diet or a lard-based HFD to induce type 2 diabetes. Then, HFD mice were fed with three different based HFD (lard, EVOO and EVOO rich in phenolic compounds) for 24 weeks. HFD-EVOO diets significantly improved glycemia, insulinemia, glucose tolerance, insulin sensitivity and insulin degradation. Moreover, EVOO diets reduced β-cell apoptosis, increased β-cell number and normalized islet glucose metabolism and glucose induced insulin secretion. No additional effects were observed by higher levels of phenolic compounds. Thus, EVOO intake regulated glucose homeostasis by improving insulin sensitivity and pancreatic β-cell function, in a type 2 diabetes HFD animal model.We thank Dr. Raquel Araujo and Antonio Cardenas for their technical assistance. We thank Dr. Alex Rafacho for his help with the analysis of the glucose decay constant rate during the ITT test and for his comments on the figures of the manuscript. We thank Dr. Irene Cozar for her help with liver insulin degrading enzyme experiments.Peer reviewe

Conservation of Phenotypes in the Roman High- and Low-Avoidance Rat Strains After Embryo Transfer

The Roman high- (RHA-I) and low-avoidance (RLA-I) rat strains are bi-directionally bred for their good versus non-acquisition of two-way active avoidance, respectively. They have recently been re-derived through embryo transfer (ET) to Sprague-Dawley females to generate specific pathogen free (SPF) RHA-I/RLA-I rats. Offspring were phenotyped at generations 1 (G1, born from Sprague-Dawley females), 3 and 5 (G3 and G5, born from RHA-I and RLA-I from G2-G4, respectively), and compared with generation 60 from our non-SPF colony. Phenotyping included two-way avoidance acquisition, context-conditioned fear, open-field behaviour, novelty-seeking, baseline startle, pre-pulse inhibition (PPI) and stress-induced increase in plasma corticosterone concentration. Post-ET between-strain differences in avoidance acquisition, context-conditioned freezing and novelty-induced self-grooming are conserved. Other behavioural traits (i.e. hole-board head-dipping, novel object exploration, open-field activity, startle, PPI) differentiate the strains at G3-G5 but not at G1, suggesting that the pre-/post-natal environment may have influenced these co-segregated traits at G1, though further selection pressure along the subsequent generations (G1-G5) rescues the typical strain-related differences

The Calaiza landslide on the coast of Granada (Andalusia, Spain)

The Costa Tropical in Granada Province, in Southern Spain, was intensively developed during the 1980s and 90s. A complex of several residential communities was built on the eastern slope of the coastal Cerro Gordo hill (Almuñécar), on the pre-existing Calaiza landslide. This was not identified in the preliminary technical studies, thus giving rise to a set of incidents associated with this unforeseen unstable slope. To ensure sea views from all the houses, excavations and fillings were carried out, creating a stepped slope, on which the new foundations of structures and roads were located and subsequently damaged by an increasing number of cracks and deformations, leading to 42 houses becoming ruins in the period 2003–2016. Since 1990, annual and monthly rainfall has been variable in the area, and some rainfall peaks were eventually associated with damage proliferation, although more frequently damage was recorded during dry or low rainfall seasons, when water infiltrated from breaks in pipelines. This damage results from a combination of sliding and bad construction practices at increasing rates from dry to humid periods or during heavy rains. An overall perspective of the geotechnical and geomorphological features of the study area, the landslide reactivation, and its correlation with the damage evolution, as well as its legal consequences, is presented here.Fundación de la Universidad de Granada para Servicios Externos (FEUGR) y representantes de las comunidades residenciales del complejo urbano durante el periodo 2005-2010Grupo RNM 121 del Plan Andaluz de Investigació

Containment measures

OBSOLETE (project finished) - Description of containment measures during COVID'19 lockdown, in the context of SIlent Cities project. Please request access to Silent Cities if neede

Archived - General Information (DO NOT USE)

DO NOT USE - The goal of this component was to document the data collection process of the Silent Cities Dataset. This component is just left for archive