Operational guidance: information needed to support clinical trials of herbal products

19 p.A tradução do original publicado em 2005 pela OMS, traz recomendações com o objetivo de fornecer o embasamento adequado para a realização de ensaios clínicos com plantas medicinais e com fitoterápicos a fim de que que possam ser aprovados pelas agências regulatórias nacionais. Esse processo aumentaria as chances de determinar quais são as plantas medicinais e os fitoterápicos que apresentam efetividade e segurança para o uso na prátic

Perspectiva para gestão do trabalho no Sistema Único de Saúde

136 p.Este documento visa o fortalecimento da capacidade técnico política das instituições do Sistema Único de Saúde na área de desenvolvimento de recursos humanos. Aborda o processo de trabalho em saúde e suas dimensões gerenciais; descreve analiticamente o ordenamento institucional e jurídico da administração de pessoal no serviço público brasileiro; relata experiências inovadoras na gestão de recursos humanos desenvolvida em diversos países latino-americanos e aborda a questão dos sistemas de compensação do trabalho em organizações de saúde

The safe motherhood referral system to reduce cesarean sections and perinatal mortality - a cross-sectional study [1995-2006]

<p>Abstract</p> <p>Background</p> <p>In 2000, the eight Millennium Development Goals (MDGs) set targets for reducing child mortality and improving maternal health by 2015.</p> <p>Objective</p> <p>To evaluate the results of a new education and referral system for antenatal/intrapartum care as a strategy to reduce the rates of Cesarean sections (C-sections) and maternal/perinatal mortality.</p> <p>Methods</p> <p><it>Design</it>: Cross-sectional study. <it>Setting</it>: Department of Gynecology and Obstetrics, Botucatu Medical School, Sao Paulo State University/UNESP, Brazil. <it>Population</it>: 27,387 delivering women and 27,827 offspring. <it>Data collection</it>: maternal and perinatal data between 1995 and 2006 at the major level III and level II hospitals in Botucatu, Brazil following initiation of a safe motherhood education and referral system. <it>Main outcome measures</it>: Yearly rates of C-sections, maternal (/100,000 LB) and perinatal (/1000 births) mortality rates at both hospitals. <it>Data analysis</it>: Simple linear regression models were adjusted to estimate the referral system's annual effects on the total number of deliveries, C-section and perinatal mortality ratios in the two hospitals. The linear regression were assessed by residual analysis (Shapiro-Wilk test) and the influence of possible conflicting observations was evaluated by a diagnostic test (Leverage), with <it>p </it>< 0.05.</p> <p>Results</p> <p>Over the time period evaluated, the overall C-section rate was 37.3%, there were 30 maternal deaths (maternal mortality ratio = 109.5/100,000 LB) and 660 perinatal deaths (perinatal mortality rate = 23.7/1000 births). The C-section rate decreased from 46.5% to 23.4% at the level II hospital while remaining unchanged at the level III hospital. The perinatal mortality rate decreased from 9.71 to 1.66/1000 births and from 60.8 to 39.6/1000 births at the level II and level III hospital, respectively. Maternal mortality ratios were 16.3/100,000 LB and 185.1/100,000 LB at the level II and level III hospitals. There was a shift from direct to indirect causes of maternal mortality.</p> <p>Conclusions</p> <p>This safe motherhood referral system was a good strategy in reducing perinatal mortality and direct causes of maternal mortality and decreasing the overall rate of C-sections.</p