7 research outputs found
Application of Gold Nanoseeds in Surface- Enhanced Raman Spectroscopy for Detection of Urea
This paper reports a study to detect urea by a homemade surface-enhanced Raman Spectroscopy (SERS) sensor using gold- nanoseeds (AuNS). The nanoseeds were prepared by the first of two steps of the seed-mediated technique where the sizes of the nanoseeds were controlled through the heat treatment periods. It was demonstrated that gold- nanoseeds (AuNS) with the averages sizes of 15-20 nm can be utilized to enhance the Raman peaks intensities of urea. The enhancement intensities of the Raman peaks are linear with the urea concentrations where the lowest urea concentration that was detected using AuNS from this study is 0.0901 g/L.
Synthesis of silver–platinum nanoferns substrates used in surface-enhanced Raman spectroscopy sensors to detect creatinine
Creatinine is one of the most commonly used bio markers of renal function. This paper reports a study on detection of creatinine using silver–platinum (AgPt) nanoferns substrates to fabricate a surface-enhanced Raman spectroscopy (SERS) sensor. The AgPt nanoferns were synthesized by liquid phase deposition (LPD) where the morphology structures and thickness of the AgPt nanoferns were controlled by varying the concentration of formic acid which was acting as the reducing agent. We have obtained four different nanoferns structures and thicknesses. This study showed that the AgPt nanoferns structure synthesized with 40 mM formic acid give the highest Raman peak intensity for a 0.05 M creatinine sample
Optimum growth time in AgPt nanofern preparation for enhancement of surface-enhanced Raman scattering intensity
Surface-enhanced Raman scattering (SERS) is a phenomenon where the signal of the Raman spectrum of an analyte increased due to a plasmonic effect of metal nanoparticles. This phenomenon is potentially be implemented in biosensor application to detect the presence of a molecule in blood and urine. This paper reports a study on bimetallic thin film of argentum-platinum (AgPt) nanoferns as a SERS substrate for detection of creatinine. Nanofern-shaped AgPt was prepared directly on ITO surface using liquid phase deposition technique. The growth time of the AgPt preparation was varied from 5 to 60 min to study the effect of growth time towards deposition of AgPt nanofern on the surface. This sensitivity of SERS measurement was studied by comparing the Raman spectra of creatinine on ITO surface and creatinine on AgPt surface. We observed that the sensitivity of the spectroscopy system towards creatinine molecule detection is dependent on the morphology structures of AgPt substrate