Efficacy of Animal-Assisted Therapy Across Pediatric Care Settings: A Systematic Review

With alternative therapies and complementary medicine becoming increasingly popular and supported by research, it is important for healthcare workers to be prepared to encounter and use these therapies in practice. A common problem in the pediatric healthcare setting is stress in patients and families during healthcare treatment. Animal assisted therapy (AAT), more commonly known as pet therapy, is a form of complementary alternative therapy that has been examined in this population. The purpose of this systematic review is to explore the effect of AAT on treatment outcomes in pediatric patients across clinical settings. The methods used to guide this systematic review include unbiased selection of twenty primary sources using the CINAHL, PsychINFO, PubMed, and Medline databases. Evidence from research shows mixed, but generally positive, results about effect of AAT on anxiety levels, pain, behavior, and treatment outcomes. Therefore AAT may be a beneficial alternative therapy for this population

Functional Diversification after Gene Duplication: Paralog Specific Regions of Structural Disorder and Phosphorylation in p53, p63, and p73

Conformational and functional flexibility promote protein evolvability. High evolvability allows related proteins to functionally diverge and perhaps to neostructuralize. p53 is a multifunctional protein frequently referred to as the Guardian of the Genome–a hub for e.g. incoming and outgoing signals in apoptosis and DNA repair. p53 has been found to be structurally disordered, an extreme form of conformational flexibility. Here, p53, and its paralogs p63 and p73, were studied for further insights into the evolutionary dynamics of structural disorder, secondary structure, and phosphorylation. This study is focused on the post gene duplication phase for the p53 family in vertebrates, but also visits the origin of the protein family and the early domain loss and gain events. Functional divergence, measured by rapid evolutionary dynamics of protein domains, structural properties, and phosphorylation propensity, is inferred across vertebrate p53 proteins, in p63 and p73 from fish, and between the three paralogs. In particular, structurally disordered regions are redistributed among paralogs, but within clades redistribution of structural disorder also appears to be an ongoing process. Despite its deemed importance as the Guardian of the Genome, p53 is indeed a protein with high evolvability as seen not only in rearranged structural disorder, but also in fluctuating domain sequence signatures among lineages

New Kent County, Virginia - Shoreline Inventory Report: Methods and Guidelines

The 2018 Inventory for New Kent County was generated using on-screen, digitizing techniques in ArcGIS® -ArcMap v10.4.1 while viewing conditions observed in Bing high resolution oblique imagery, Google Earth, and 2017 imagery from the Virginia Base Mapping Program (VBMP). Four GIS shapefiles are developed. The first describes land use and bank conditions (New_Kent_lubc_2018). The second portrays the presence of beaches (New_Kent_beaches_2018). The third reports shoreline structures that are described as arcs or lines(e.g. riprap)(New_Kent_sstru_2018). The final shapefile includes all structures that are represented as points(e.g. piers)(New_Kent_astru_2018).The metadata file accompanies the shapefiles and defines attribute accuracy, data development, and any use restrictions that pertain to data

Summary Tables: 2018 New Kent County, Virginia Shoreline Inventory

The Shoreline Inventory Summary Tables quantify observed conditions based on river systems, such as the combined length of linear features (e.g. shoreline miles surveyed, miles of bulkhead and revetment), the total number of point features (e.g. docks, boathouses, boat ramps) & total acres of polygon features (tidal marshes)

Summary Tables: 2018 Caroline County, Virginia Shoreline Inventory

The Shoreline Inventory Summary Tables quantify observed conditions based on river systems, such as the combined length of linear features (e.g. shoreline miles surveyed, miles of bulkhead and revetment), the total number of point features (e.g. docks, boathouses, boat ramps) & total acres of polygon features (tidal marshes)

Summary Tables: 2018 Richmond County, Virginia Shoreline Inventory

The Shoreline Inventory Summary Tables quantify observed conditions based on river systems, such as the combined length of linear features (e.g. shoreline miles surveyed, miles of bulkhead and revetment), the total number of point features (e.g. docks, boathouses, boat ramps) & total acres of polygon features (tidal marshes)

Summary Tables: 2018 Essex County, Virginia Shoreline Inventory Report

The Shoreline Inventory Summary Tables quantify observed conditions based on river systems, such as the combined length of linear features (e.g. shoreline miles surveyed, miles of bulkhead and revetment), the total number of point features (e.g. docks, boathouses, boat ramps) & total acres of polygon features (tidal marshes)