145 research outputs found

    Understanding the mechanism of warming amplification in the Arctic: Contributions of the global modeling studies to the GRENE Arctic climate change research project

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    第6回極域科学シンポジウム特別セッション:[S] 北極温暖化とその影響 ―GRENE 北極気候変動プロジェクトと新しい方向性―11月18日(水) 国立極地研究所 2階 大会議

    Centromere/kinetochore is assembled through CENP-C oligomerization

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    Kinetochore is an essential protein complex required for accurate chromosome segregation. The constitutive centromere-associated network (CCAN), a subcomplex of the kinetochore, associates with centromeric chromatin and provides a platform for the kinetochore assembly. The CCAN protein CENP-C is thought to be a central hub for the centromere/kinetochore organization. However, the role of CENP-C in CCAN assembly needs to be elucidated. Here, we demonstrate that both the CCAN-binding domain and the C-terminal region that includes the Cupin domain of CENP-C are necessary and sufficient for chicken CENP-C function. Structural and biochemical analyses reveal self-oligomerization of the Cupin domains of chicken and human CENP-C. We find that the CENP-C Cupin domain oligomerization is vital for CENP-C function, centromeric localization of CCAN, and centromeric chromatin organization. These results suggest that CENP-C facilitates the centromere/kinetochore assembly through its oligomerization.Hara M., Ariyoshi M., Sano T., et al. Centromere/kinetochore is assembled through CENP-C oligomerization. Molecular Cell 83, 2188 (2023); https://doi.org/10.1016/j.molcel.2023.05.023

    Large-scale variations of the energy-water balance on land at high latitudes - Analysis using a wetness index -

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    第3回極域科学シンポジウム/特別セッション「これからの北極研究」11月28日(水) 国立極地研究所 2階大会議

    A statistical study of convective and dynamic instabilities in the polar upper mesosphere above Tromsø

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    We have studied the convective (or static) and dynamic instabilities between 80 and 100 km above Tromsø (69.6° N, 19.2° E) using temperature and wind data of 6 min and 1 km resolutions primarily almost over a solar cycle obtained with the sodium lidar at Tromsø. First, we have calculated Brunt–Väisälä frequency (N) for 339 nights obtained from October 2010 to December 2019, and the Richardson number (Ri) for 210 nights obtained between October 2012 to December 2019. Second, using those values (N and Ri), we have calculated probabilities of the convective instability (N2<0) and the dynamic instability (0≤Ri<0.25) that can be used for proxies for evaluating the atmospheric stability. The probability of the convective instability varies from about 1% to 24% with a mean value of 9%, and that of the dynamic instability varies from 4 to 20% with a mean value of 10%. Third, we have compared these probabilities with the F10.7 index and local K-index. The probability of the convective instability shows a dependence (its correlation coefcient of 0.45) of the geomagnetic activity (local K-index) between 94 and 100 km, suggesting an auroral infuence on the atmospheric stability. The probability of the dynamic instability shows a solar cycle dependence (its correlation coefcient being 0.54). The probability of the dynamic instability shows the dependence of the 12 h wave amplitude (meridional and zonal wind components) (C.C.=0.52). The averaged potential energy of gravity waves shows decrease with height between 81 and 89 km, suggesting that dissipation of gravity waves plays an important role (at least partly) in causing the convective instability below 89 km. The probability of the convective instability at Tromsø appears to be higher than that at middle/low latitudes, while the probability of the dynamic instability is similar to that at middle/low latitudes

    Arctic challenge - our research strategy for Arctic climate change

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    第3回極域科学シンポジウム/特別セッション「これからの北極研究」11月28日(水) 国立極地研究所 2階大会議

    Dissipative Field Theory with Caldeira-Leggett Method and its Application to Disoriented Chiral Condensation

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    The effective field theory including the dissipative effect is developed based on the Caldeira-Leggett theory at the classical level. After the integration of the small field fluctuations considered as the field radiation, the integro-differential field equation is given and shown to include the dissipative effects. In that derivation, special cares should be taken for the boundary condition of the integration. Application to the linear sigma model is given, and the decay process of the chiral condensate is calculated with it, both analytically in the linear approximation and numerically. With these results, we discuss the stability of chiral condensates within the quenched approximation.Comment: 16pages, ReV-Te

    Relationship between retreating sea ice and trend of cloud cover over the Arctic Ocean in Coupled GCM, MIROC

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    第3回極域科学シンポジウム/特別セッション「これからの北極研究」11月28日(水) 国立極地研究所 2階大会議
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