Isolated output for class-D dc amplifiers

Transformer-coupled output stage is used with pulse-width modulated class-D dc amplifiers. Circuit is comprised of two channels corresponding to negative and positive input signals. Amplitude of secondary-current triangular pulse is function of duration of driving pulse. Therefore, circuit converts pulse-width modulated driving signal to pulse-amplitude modulated signal

The role of impulse parameters in force variability

One of the principle limitations of the human motor system is the ability to produce consistent motor responses. When asked to repeatedly make the same movement, performance outcomes are characterized by a considerable amount of variability. This occurs whether variability is expressed in terms of kinetics or kinematics. Variability in performance is of considerable importance because for tasks requiring accuracy it is a critical variable in determining the skill of the performer. What has long been sought is a description of the parameter or parameters that determine the degree of variability. Two general experimental protocals were used. One protocal is to use dynamic actions and record variability in kinematic parameters such as spatial or temporal error. A second strategy was to use isometric actions and record kinetic variables such as peak force produced. What might be the important force related factors affecting variability is examined and an experimental approach to examine the influence of each of these variables is provided

Evaluating three frameworks for the value of information: adaptation to task characteristics and probabilistic structure

We identify, and provide an integration of, three frameworks for measuring the informativeness of cues in a multiple-cue judgment task. Cues can be ranked by information value according to expected information gain (Bayesian framework), cue-outcome correlation (Correlational framework), or ecological validity (Ecological framework). In three experiments, all frameworks significantly predicted information acquisition, with the Correlational (then the Bayesian) framework being most successful. Additionally, participants adapted successfully to task characteristics (cue cost, time pressure, and information limitations) – altering the gross amount of information acquired, but not responding to more subtle features of the cues’ information value that would have been beneficial. Rational analyses of our task environments indicate that participants' behavior can be considered successful from a boundedly rational standpoint

An Analysis of Kinetic Response Variability

Studies evaluating variability of force as a function of absolute force generated are synthesized. Inconsistencies in reported estimates of this relationship are viewed as a function of experimental constraints imposed. Typically, within-subject force variability increases at a negative accelerating rate with equal increments in force produced. Current pulse-step and impulse variability models are unable to accommodate this description, although the notion of efficiency is suggested as a useful construct to explain the description outlined

Hamara Healthy Living Centre - an evaluation

Hamara is a Healthy Living Centre which aims to improve health and well-being through providing a range of culturally appropriate activities and services. Hamara has a vision of 'bringing communities together' and since it was established in 2004, the Centre has provided a valuable community resource in South Leeds. Partnership work between Hamara and Leeds Met goes back to 2002. In 2007, the Centre for Health Promotion Research carried out an evaluation of Hamara in partnership with Hamara staff and Leeds Met Community Partnerships and Volunteering. This was followed by a highly successful community cohesion conference 'One Community' which was held at Hamara on 10th October 2008, and was supported through a Leeds Met public engagement grant. The event attracted over a hundred people from diverse communities and organisations across Leeds. A packed audience heard Hilary Benn, local MP and Patron of Hamara, talk about the importance of working in collaboration around community cohesion. Jane South, Centre for Health Promotion Research, presented the main evaluation results and set out the some challenges for the future. The proceedings concluded with the presentation of awards to a number of for local community champions who work to bring people together and make a real difference in the city of Leeds

Aging, Neuromuscular Decline, and the Change in Physiological and Behavioral Complexity of Upper-Limb Movement Dynamics

Aging is characterized by a general decline in physiological and behavioral function that has been widely interpreted within the context of the loss of complexity hypothesis. In this paper, we examine the relation between aging, neuromuscular function and physiological-behavioral complexity in the arm-hand effector system, specifically with reference to physiological tremor and isometric force production. Experimental findings reveal that the adaptive behavioral consequences of the aging-related functional decline in neurophysiological processes are less pronounced in simple motor tasks which provides support for the proposition that the motor output is influenced by both extrinsic (e.g., task related) and intrinsic (e.g., coordination, weakness) factors. Moreover, the aging-related change in complexity can be bidirectional (increase or decrease) according to the influence of task constraints on the adaptation required of the intrinsic properties of the effector system

Human resources needs for universal access to antiretroviral therapy in South Africa: a time and motion study

<p>Background - Although access to life-saving treatment for patients infected with HIV in South Africa has improved substantially since 2004, treating all eligible patients (universal access) remains elusive. As the prices of antiretroviral drugs have dropped over the past years, availability of human resources may now be the most important barrier to achieving universal access to HIV treatment in Africa. We quantify the number of HIV health workers (HHWs) required to be added to the current HIV workforce to achieve universal access to HIV treatment in South Africa, under different eligibility criteria.</p> <p>Methods - We performed a time and motion study in three HIV clinics in a rural, primary care-based HIV treatment program in KwaZulu-Natal, South Africa, to estimate the average time per patient visit for doctors, nurses, and counselors. We estimated the additional number of HHWs needed to achieve universal access to HIV treatment within one year.</p> <p>Results - For universal access to HIV treatment for all patients with a CD4 cell count of ≤350 cells/μl, an additional 2,200 nurses, 3,800 counselors, and 300 doctors would be required, at additional annual salary cost of 929 million South African rand (ZAR), equivalent to US$141 million. For universal treatment (‘treatment as prevention’), an additional 6,000 nurses, 11,000 counselors, and 800 doctors would be required, at an additional annual salary cost of ZAR 2.6 billion (US$ 400 million).</p> <p>Conclusions - Universal access to HIV treatment for patients with a CD4 cell count of ≤350 cells/μl in South Africa may be affordable, but the number of HHWs available for HIV treatment will need to be substantially increased. Treatment as prevention strategies will require considerable additional financial and human resources commitments.</p&gt

The art of HIV elimination: past and present science

Introduction: Remarkable strides have been made in controlling the HIV epidemic, although not enough to achieve epidemic control. More recently, interest in biomedical HIV control approaches has increased, but substantial challenges with the HIV cascade of care hinder successful implementation. We summarise all available HIV prevention methods and make recommendations on how to address current challenges. Discussion: In the early days of the epidemic, behavioural approaches to control the HIV dominated, and the few available evidence-based interventions demonstrated to reduce HIV transmission were applied independently from one another. More recently, it has become clear that combination prevention strategies targeted to high transmission geographies and people at most risk of infections are required to achieve epidemic control. Biomedical strategies such as male medical circumcision and antiretroviral therapy for treatment in HIV-positive individuals and as preexposure prophylaxis in HIV-negative individuals provide immense promise for the future of HIV control. In resourcerich settings, the threat of HIV treatment optimism resulting in increased sexual risk taking has been observed and there are concerns that as ART roll-out matures in resource-poor settings and the benefits of ART become clearly visible, behavioural disinhibition may also become a challenge in those settings. Unfortunately, an efficacious vaccine, a strategy which could potentially halt the HIV epidemic, remains elusive. Conclusion: Combination HIV prevention offers a logical approach to HIV control, although what and how the available options should be combined is contextual. Therefore, knowledge of the local or national drivers of HIV infection is paramount. Problems with the HIV care continuum remain of concern, hindering progress towards the UNAIDS target of 90-90-90 by 2020. Research is needed on combination interventions that address all the steps of the cascade as the steps are not independent of each other. Until these issues are addressed, HIV elimination may remain an unattainable goal

Toda Lattice Solutions of Differential-Difference Equations for Dissipative Systems

In a certain class of differential-difference equations for dissipative systems, we show that hyperbolic tangent model is the only the nonlinear system of equations which can admit some particular solutions of the Toda lattice. We give one parameter family of exact solutions, which include as special cases the Toda lattice solutions as well as the Whitham's solutions in the Newell's model. Our solutions can be used to describe temporal-spatial density patterns observed in the optimal velocity model for traffic flow.Comment: Latex, 13 pages, 1 figur

Exact shock solution of a coupled system of delay differential equations: a car-following model

In this paper, we present exact shock solutions of a coupled system of delay differential equations, which was introduced as a traffic-flow model called {\it the car-following model}. We use the Hirota method, originally developed in order to solve soliton equations. %While, with a periodic boundary condition, this system has % a traveling-wave solution given by elliptic functions. The relevant delay differential equations have been known to allow exact solutions expressed by elliptic functions with a periodic boundary conditions. In the present work, however, shock solutions are obtained with open boundary, representing the stationary propagation of a traffic jam.Comment: 6 pages, 2 figure