A New Device Hypothesis for Water Extraction from Air and Basic Air Condition System in Developing Countries

This work proposes a new device for air treatment with dehumidification and water recovery/storage, with possible mitigation of indoor environmental conditions. The system is based on Peltier cells coupled with a horizontal earth-to-air heat exchanger, it is proposed as an easy-to-implement alternative to the heat pumps and air handling units currently used on the market, in terms of cost, ease of installation, and maintenance. The process provides the water collection from the cooling of warm-humid air through a process that leads to condensation and water vapor separation. The airflow generated by a fan splits into two dual flows that lap the two surfaces of the Peltier cells, one flow laps the cold surfaces undergoing sensible, latent cooling with dehumidification; the other flow laps the hot surfaces and heats up. The airflow undergoes thermal pre-treatment through the underground horizontal geothermal pipe that precedes the Peltier cells. In the water storage tank, which also works as a mixing chamber, the two air streams are mixed to regulate the outlet temperature. The system can be stand-alone if equipped with a photovoltaic panel and a micro wind turbine, able to be used in places where electricity is absent. The system, with different configurations, is modeled in the African city Kigali, in Rwanda

Animal-based vs plant-based protein quality. A survey of millennial students nutritional knowledge and food preferences

The food system around the mass production of meat and by-products constitutes a major driver of global warming, diminution of Earth’s resources, land degradation and deforestation, as well as contamination of aquatic and terrestrial ecosystems (IPCC, 2019; UN Environment Programme, 2018). At its current levels, worldwide food consumption practices are high, and particularly so in meat products. Proof lies in the environmental data, which is swiftly accumulating on the unsustainability of meat (Sabaté et al., 2014). At the present day, meat production is accountable for occupying over half of the Earth’s cultivable land resources and for driving greenhouse gas emissions. Supporting those findings is Eshel’s research (2014), which found that meat eaters employ over 160 percent of land resources when compared to those people who are reliant on a plant-based diet. In fact, although varying across several crop categories and regions, the global average water footprint related to crop production is remarkably lower when compared to the effect of meat production over freshwater sources (Mekonnen et al., 2012). Meat production necessitates around 2422 Gm3 of water per year, the provision of just 1 kg of animal protein demands almost 100 times more water than producing 1 kg of grain protein (Lonnie and Johnstone, 2020). As a result, only a mitigated, global shift in dietary changes that are mainly reliant on nutritionally balanced, plant-based sourced of protein could sustainably feed 10 billion people by 2050. This would guarantee nutritional adequacy, food security and food sufficiency (LEAP, 2020; Willet et al., 2019). According to the European Environment Agency (2019) there are increasing concerns related to the linkage between an excessive consumption of animal-derived proteins and issues related to health and environment. Within this context, 1 in 5 people living in the UK have already stopped or reduced their meat consumption (The Vegan Society, 2020). Currently, there is increased awareness, particularly popular within millennials, regarding the adoption of a healthy, balanced diet which includes plant-based sources of protein. A conscious consumerism is in fact driving the trend towards the consumption of novelty food, more particularly plant-based, protein-rich products. In fact, according to data collected by Proveg Int. (2019) the UK's purchase and consumption rates of vegan products, more specifically milk, meat, margarine, cheese, readymade meals, and seafood, are amongst the highest in Europe. Within this frame of perpetual development, consumers are looking beyond the label. Eager to experiment with the inclusion of a wider variety of food options into their diet, their interest in converting and expanding their palate is increasing and subject to a continuous evolution (Mintel, 2018). What used to appeal to a niche sector, is guaranteed to have a prosperous future within the food and beverage industry. In fact, vegans and vegetarians is projected to be a quarter of the British population by 2025, and flexitarians just under half of all UK consumers (Sainsbury’s, 2019). Despite the increase in the number of people switching to a plant-based diet, meat consumption remains highly ingrained in Western culture and the disposition to stop or reduce consumption of animal products therefore remains relatively low. Consumers often describe plant-based products to have unappealing taste, texture, and appearance. Meat substitutes are difficult to find, often highly priced and more challenging to cook than their meat counterparts (Forbes, 2019; Mintel, 2020). The lack of a wide array of studies conducted on the subject might be due to the concept of protein quality that remains a “grey area”. The consumption of proteins-enriched products is nothing but a relatively recent trend. The significance of this research ties back to the fact that there is a limited amount of evidence and literature related to familiarity with the concept of protein content and perceptions related to healthfulness and wellbeing. More importantly, no past research has taken into consideration millennial university students. This study aims to assess millennial university students’ nutritional knowledge and preferences related to food regimes, with a particular insight on the protein quality content of food, which focuses and distinguishes mainly between plant-based and animal-based protein sources

The impact of visiting the Intensive Care Unit (ICU) on children's and adolescents' psychological well-being: A systematic review

Abstract Objectives The visits of children/adolescents in adult intensive care units are increasingly more common. However, few studies examine the psychological impact of visiting. This systematic review aims to summarise the psychological effects that visiting family members has on children/adolescents. Research methodology A systematic review of research articles published from 1990 to January 2021 was conducted using PsycInfo, PubMed, and CINAHL. Inclusion/exclusion criteria were applied. Those studies included were evaluated using the Joanna Briggs Institute Critical Appraisal tools. A narrative synthesis of the results was conducted. Setting Adult intensive care unit. Results The review identified five studies (three of which qualitative), involving 141 children/adolescents. Although the experience of visiting was potentially traumatic, it enabled children/adolescents to better understand the reality and to preserve their relationships with family members. The impact of visiting was influenced by individual characteristics (e.g., age, past traumatic experiences) and by organisational characteristics (e.g., facilitated visit or not). Regardless of visitation, most children/adolescents presented anxiety and depression symptoms that need to be addressed. Conclusions Child/adolescent visitation seems to have positive effects, provided there is preparation and facilitation. Clinicians should pay attention to individual characteristics and optimise organisational factors (e.g., environment) in order to minimise potentially trauma-inducing aspects

Noninvasive vagus nerve stimulation as acute therapy for migraine. The randomized PRESTO study

Objective: To evaluate the efficacy, safety, and tolerability of noninvasive vagus nerve stimulation (nVNS; gammaCore; electroCore, LLC, Basking Ridge, NJ) for the acute treatment of migraine in a multicenter, double-blind, randomized, sham-controlled trial. Methods: A total of 248 participants with episodic migraine with/without aura were randomized to receive nVNS or sham within 20 minutes from pain onset. Participants were to repeat treatment if pain had not improved in 15 minutes. Results: nVNS (n = 120) was superior to sham (n = 123) for pain freedom at 30 minutes (12.7% vs 4.2%; p = 0.012) and 60 minutes (21.0% vs 10.0%; p = 0.023) but not at 120 minutes (30.4% vs 19.7%; p = 0.067; primary endpoint; logistic regression) after the first treated attack. A post hoc repeatedmeasures test provided further insight into the therapeutic benefit of nVNS through 30, 60, and 120 minutes (odds ratio 2.3; 95% confidence interval 1.2, 4.4; p = 0.012). nVNS demonstrated benefits across other endpoints including pain relief at 120minutes and was safe and well-tolerated. Conclusion: This randomized sham-controlled trial supports the abortive efficacy of nVNS as early as 30 minutes and up to 60 minutes after an attack. Findings also suggest effective pain relief, tolerability, and practicality of nVNS for the acute treatment of episodic migraine

An Agonist of the CXCR4 Receptor Strongly Promotes Regeneration of Degenerated Motor Axon Terminals

The activation of the G-protein coupled receptor CXCR4 by its ligand CXCL12\u3b1 is involved in a large variety of physiological and pathological processes, including the growth of B cells precursors and of motor axons, autoimmune diseases, stem cell migration, inflammation, and several neurodegenerative conditions. Recently, we demonstrated that CXCL12\u3b1 potently stimulates the functional recovery of damaged neuromuscular junctions via interaction with CXCR4. This result prompted us to test the neuroregeneration activity of small molecules acting as CXCR4 agonists, endowed with better pharmacokinetics with respect to the natural ligand. We focused on NUCC-390, recently shown to activate CXCR4 in a cellular system. We designed a novel and convenient chemical synthesis of NUCC-390, which is reported here. NUCC-390 was tested for its capability to induce the regeneration of motor axon terminals completely degenerated by the presynaptic neurotoxin \u3b1-Latrotoxin. NUCC-390 was found to strongly promote the functional recovery of the neuromuscular junction, as assayed by electrophysiology and imaging. This action is CXCR4 dependent, as it is completely prevented by AMD3100, a well-characterized CXCR4 antagonist. These data make NUCC-390 a strong candidate to be tested in human therapy to promote nerve recovery of function after different forms of neurodegeneratio

Investigation on the Loss of Taste and Smell and Consequent Psychological Effects: A Cross-Sectional Study on Healthcare Workers Who Contracted the COVID-19 Infection

The aim of this study was to investigate the correlation between psychological distress and taste and sense of smell dysfunctions on healthcare workers (HCW) who contracted the COVID-19 infection in the midst of the disease outbreak. Reports of sudden loss of taste and smell which persist even after recovery from COVID-19 infection are increasingly recognized as critical symptoms for COVID-19 infections. Therefore, we conducted a cross-sectional study on COVID-19 HCW (N = 104) who adhered to respond to a phone semistructured interview addressing the virus symptoms and associated psychological distress. Data were collected from June to September 2020. Findings confirm the association between experienced taste/olfactory loss and emotional distress and suggest that dysfunctions of taste and smell correlate positively with anxiety and depression. Furthermore, their psychological impact tends to persist even after the recovery from the disease, suggesting the need for appropriate psychological interventions to prevent people from developing more serious or long-lasting psychological disorders and, as far as HCW, to reduce the risk of work-related distress

Development and validation of the ID-EC - The ITALIAN version of the identify chronic migraine

Background: Case-finding tools, such as the Identify Chronic Migraine (ID-CM) questionnaire, can improve detection of CM and alleviate its significant societal burden. We aimed to develop and validate the Italian version of the ID-CM (ID-EC) in paper and as a smart app version in a headache clinic-based setting. Methods: The study investigators translated and adapted to the Italian language the original ID-CM questionnaire (ID-EC) and further implemented it as a smart app. The ID-EC was tested in its paper and electronic version in consecutive patients referring to 9 Italian tertiary headache centers for their first in-person visit. The scoring algorithm of the ID-EC paper version was applied by the study investigators (case-finding) and by patients (self-diagnosis), while the smart app provided to patients automatically the diagnosis. Diagnostic accuracy of the ID-EC was assessed by matching the questionnaire results with the interview-based diagnoses performed by the headache specialists during the visit according to the criteria of International Classification of Headache Disorders, III edition, beta version. Results: We enrolled 531 patients in the test of the paper version of ID-EC and 427 in the validation study of the smart app. According to the clinical diagnosis 209 patients had CM in the paper version study and 202 had CM in the smart app study. 79.5% of patients returned valid paper questionnaires, while 100% of patients returned valid and complete smart app questionnaires. The paper questionnaire had a 81.5% sensitivity and a 81.1% specificity for case-finding and a 30.7% sensitivity and 90.7% specificity for self-diagnosis, while the smart app had a 64.9% sensitivity and 90.2% specificity. Conclusions: Our data suggest that the ID-EC, developed and validated in tertiary headache centers, is a valid case-finding tool for CM, with sensitivity and specificity values above 80% in paper form, while the ID-EC smart app is more useful to exclude CM diagnosis in case of a negative result. Further studies are warranted to assess the diagnostic accuracy of the ID-EC in general practice and population-based settings

Gen Z’s Willingness to Adopt Plant-Based Diets: Empirical Evidence from Greece, India, and the UK [Preprint]

Comprising the largest population cohort on this planet, Gen Z presents a future-oriented consumer segment driven by climate change and food. This study sought to investigate Gen Z’s perceptions toward plant-based foods and diets and explore the relationship that attitude components, meal preparation involvement, personal and lifestyle factors, and perceived barriers in adopting a plant-based diet have with willingness to adopt green-eating practices. Using cross-sectional data from university students in Greece, India, and the UK, various tools were employed to determine the factors influencing youths’ consumer behaviour toward animal-protein substitutes. PCA indicated the underlying dimensions of students’ viewpoints on plant-based foods, whereas hierarchical and k-means clustering provided the cluster structure. An ordered probit model was estimated to delineate Gen Z’s willingness to adopt plant-based diets and distinguish among mostly unwilling, somewhat willing, and mostly willing youths. Our findings identified two consumer segments, namely proponents and opponents of plant-based foods and diets, with statistically significant differences in the perceived health benefits of plant-based diets, attachment to animal-based proteins, perceived exclusion of animal-based foods, dissatisfaction with plant-based foods’ attributes, and demand for ensuring adequate protein intake. The ordered probit model estimates showed that there is a «homogeneity» in the factors influencing youths’ intention to adopt plant-based diets, with attitude components, meal preparation indicators, perceived barriers to eating “green”, and personal factors, such as self-assessed knowledge of healthy eating and physical activity, being strongly associated with students’ willingness to switch to plant-based diets in all three countries. Mapping potential obstacles and enablers in terms of shifting to more green-eating behaviours, our findings could add information to better understand the factors affecting food choice and youths’ transition to a more sustainable lifestyle

How to communicate with families living in complete isolation

The global emergency caused by the SARS-CoV-2 pandemic has suddenly changed how we communicate with families in all the CoViD19 care settings, on account of the need to maintain complete social isolation. Far-reaching mental suffering manifests itself in widespread anxiety. Health workers are isolated from their families, and must manage the consequences of this isolation just like the patients under their care. Patients and their families perceive not only the clinical results but also the personal attitudes, closeness and psychological support from the care teams. This perception of genuine participation by the health worker in the course of the treatment is especially important when a patient dies, and may influence the whole process of grief