A Study on Geometry Contrast Enhancement for 3D Point Models

Electrical EngineeringPoint primitives have come into the spotlight as a representation method of 3D models. A lot of researches have been performed on the modeling, processing, and rendering 3D point models. Especially, various methods have been developed for the extraction and preservation of the salient features of corners, curves, and edges in 3D point models. However, little effort has been made to extract and enhance the weak features that are relatively imperceptible due to the low geometry contrast. In this thesis, we propose a novel method to improve the visibility of 3D point models by enhancing the geometry contrast of weak features. We first define a weak feature region as a group of local points yielding small deviations of normal directions. Then we define the geometry histogram for each region as the distribution of the signed distance between a feature point and the locally approximated plane. We equalize and stretch the geometry histogram and move the corresponding feature points accordingly. We also render the enhanced model using the normal mapping for better visual presentation. Experimental results demonstrate that the proposed method enhances the geometry contrast of 3D point models by refining the appearance of the weak features. We expect that the geometry contrast enhancement algorithm will facilitate many applications in various fields.ope

Hull-form optimization of a 66,000 dwt bulk carrier in irregular wave condition

This paper deploys optimization techniques to obtain the optimum hull form of a 66,000 DWT bulk carrier in calm water and in irregular head waves at sea state 6. Parametric modification functions for the bow hull-form variation are SAC shape, section shape (U-V type, DLWL type). Multi-objective functions are applied to minimize the values of wave-making resistance in calm water and mean added resistance in waves. WAVIS version 1.3 is used to obtain wave-making resistance in calm water condition. The modified Fujii and Takahashi's formula is applied to obtain the added resistance in short waves. The added resistance in long wave is obtained from the potential-flow solver based on the 3-D panel method. And the mean added resistance in irregular head waves is obtained by linear superposition of the wave spectrum and the response function. The PSO (Particle swarm optimization) algorithm is employed for the optimization technique. The resistance and motion characteristics in calm water, in regular head waves and in irregular head waves of the two hull forms are compared. It has been shown that the optimal brings 6.8% reduction in the mean added resistance at sea state 6

Generation of subspecies level-specific microbial diagnostic microarrays using genes amplified from subtractive suppression hybridization as microarray probes

The generation of microarray probes with specificity below the species level is an ongoing challenge, not least because the high-throughput detection of microorganisms would be an efficient means of identifying environmentally relevant microbes. Here, we describe how suppression subtractive hybridization (SSH) can be applied to the production of microarray probes that are useful for microbial differentiation at the subspecies level. SSH was used to initially isolate unique genomic sequences of nine Salmonella strains, and these were validated in quadruplicate by microarray analysis. The results obtained indicate that a large group of genes subtracted by SSH could serve together, as one probe, for detecting a microbial subspecies. Similarly, the whole microbial genome (not subjected to SSH) can be used as a species-specific probe. The detailed methods described herein could be used and adapted for the estimation of any cultivable bacteria from different environments

Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury

TonEBP (tonicity-responsive enhancer binding protein) is a transcriptional regulator whose expression is elevated in response to various forms of stress including hyperglycemia, inflammation, and hypoxia. Here we investigated the role of TonEBP in acute kidney injury (AKI) using a line of TonEBP haplo-deficient mice subjected to bilateral renal ischemia followed by reperfusion (I/R). In the TonEBP haplo-deficient animals, induction of TonEBP, oxidative stress, inflammation, cell death, and functional injury in the kidney in response to I/R were all reduced. Analyses of renal transcriptome revealed that genes in several cellular pathways including peroxisome and mitochondrial inner membrane were suppressed in response to I/R, and the suppression was relieved in the TonEBP deficiency. Production of reactive oxygen species (ROS) and the cellular injury was reproduced in a renal epithelial cell line in response to hypoxia, ATP depletion, or hydrogen peroxide. The knockdown of TonEBP reduced ROS production and cellular injury in correlation with increased expression of the suppressed genes. The cellular injury was also blocked by inhibitors of necrosis. These results demonstrate that ischemic insult suppresses many genes involved in cellular metabolism leading to local oxidative stress by way of TonEBP induction. Thus, TonEBP is a promising target to prevent AKI

Anti-Apoptotic Effects of SERPIN B3 and B4 via STAT6 Activation in Macrophages after Infection with Toxoplasma gondii

Toxoplasma gondii penetrates all kinds of nucleated eukaryotic cells but modulates host cells differently for its intracellular survival. In a previous study, we found out that serine protease inhibitors B3 and B4 (SERPIN B3/B4 because of their very high homology) were significantly induced in THP-1-derived macrophages infected with T. gondii through activation of STAT6. In this study, to evaluate the effects of the induced SERPIN B3/B4 on the apoptosis of T. gondii-infected THP-1 cells, we designed and tested various small interfering (si-) RNAs of SERPIN B3 or B4 in staurosporine-induced apoptosis of THP-1 cells. Anti-apoptotic characteristics of THP-1 cells after infection with T. gondii disappeared when SERPIN B3/B4 were knock-downed with gene specific si-RNAs transfected into THP-1 cells as detected by the cleaved caspase 3, poly-ADP ribose polymerase and DNA fragmentation. This anti-apoptotic effect was confirmed in SERPIN B3/B4 overexpressed HeLa cells. We also investigated whether inhibition of STAT6 affects the function of SERPIN B3/B4, and vice versa. Inhibition of SERPIN B3/B4 did not influence STAT6 expression but SERPIN B3/B4 expression was inhibited by STAT6 si-RNA transfection, which confirmed that SERPIN B3/B4 was induced under the control of STAT6 activation. These results suggest that T. gondii induces SERPIN B3/B4 expression via STAT6 activation to inhibit the apoptosis of infected THP-1 cells for longer survival of the intracellular parasites themselves

Design for Sharing Emotional Touches during Phone Calls: A Quantitative Evaluation of Four Tactile Representations

Background As the importance of mobile phones as an emotional communication medium is growing, non-verbal behaviors such as facial expressions, touching behaviors and gestures ought to be considered to enhance phone conversations. Among various non-verbal signals, we focus on sharing specific touches that could be used for exchanging contextual and emotional cues. Along with this, to make the new phone conversation involving touching more natural, we consider maintaining natural audio conversation with phones by keeping the receiver on the ear and the transmitter on the mouth while holding the phone to the cheek. Methods In this paper, we focus on investigating ways to deliver four touches: pat, slap, tickle and kiss with sound and tactile feedback while holding the phone to the cheek as in typical phone calls. The interaction technique is called CheekTouch, and it is based on enabling users to share touches by representing finger gestures on one phone screen to the other party???s cheek using a vibrotactile display and sound stimulations. We asked the 30 students who participated to put the device on their cheek and wear earphones, and we provided them with 24 different stimulations. Results An evaluation was conducted to propose the most appropriate type of stimulation to deliver a pat, slap, tickle and kiss using CheekTouch. We showed that the best way to deliver a pat was to use a vibrotactile display combined with sound; however, a tickle was best delivered with only the vibrotactile display. A kiss and slap, on the other hand, were best delivered when there was only sound. Conclusions Considering the trends in sharing delicate emotions during phone-mediated communications, it is significant to investigate ways to convey touches during phone conversations beyond sharing visual emoticons. Here, we focused on findings ways to pat, slap, tickle and kiss by using existing phone technologies (vibrotactile motors and sound). Through the quantitative evaluation of those four touches, we discovered which stimulation type is best for delivering each of the touches. The results do not show whether those touches can deliver emotions, however, we believe CheekTouch and the findings from the evaluation can be used for sharing different types of non-verbal signals during audio-based phone conversations and enable further studies in the field of remote tactile interaction.clos

Comparison of the risks of occupational diseases, avoidable hospitalization, and all-cause deaths between firefighters and non-firefighters: A cohort study using national health insurance claims data

ObjectivesNational Health Insurance claims data were used to compare the incidence of occupational diseases, avoidable hospitalization, and all-cause death standardized incidence ratio and hazard ratio between firefighters and non-firefighters.MethodsThe observation period of the study was from 2006 to 2015 and a control group (general workers and national and regional government officers/public educational officers) and a firefighter group was established. The dependent variables were occupational diseases, avoidable hospitalization (AH), and all-cause death. The analysis was conducted in three stages. First, the standardized incidence ratios were calculated using the indirect standardization method to compare the prevalence of the disease between the groups (firefighter and non-firefighter groups). Second, propensity score matching was performed for each disease in the control group. Third, the Cox proportional hazards model was applied by matching the participants.ResultsThe standardized incidence ratio and Cox regression analyses revealed higher rates of noise-induced hearing loss, ischemic heart disease, asthma, chronic obstructive pulmonary disease, cancer, back pain, admission due to injury, mental illness, depression, and AH for firefighters than general workers. Similarly, the rates of noise-induced hearing loss, ischemic heart disease, asthma, chronic obstructive pulmonary disease, back pain, admission due to injury, mental illness, depression, and AH were higher in the firefighter group than in the national and regional government officer/public educational officer group.ConclusionsThe standardized incidence ratios and hazard ratios for most diseases were high for firefighters. Therefore, besides the prevention and management of diseases from a preventive medical perspective, management programs, including social support and social prescriptions in the health aspect, are needed

Palladium Catalysts for Dehydrogenation of Ammonia Borane with Preferential B−H Activation

Cationic Pd(II) complexes catalyzed the dehydrogenation of ammonia borane in the most efficient manner with the release of 2.0 equiv of H_2 in less than 60 s at 25 °C. Most of the hydrogen atoms were obtained from the boron atom of the ammonia borane. The first step of the dehydrogenation reaction was elaborated using density functional theory calculations