26,850 research outputs found

    Comment of Global dynamics of biological systems

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    In a recent study, (Grigorov, 2006) analyzed temporal gene expression profiles (Arbeitman et al., 2002) generated in a Drosophila experiment using SSA in conjunction with Monte-Carlo SSA. The author (Grigorov, 2006) makes three important claims in his article, namely: Claim1: A new method based on the theory of nonlinear time series analysis is used to capture the global dynamics of the fruit-fly cycle temporal gene expression profiles. Claim 2: Flattening of a significant part of the eigen-spectrum confirms the hypothesis about an underly-ing high-dimensional chaotic generating process. Claim 3: Monte-Carlo SSA can be used to establish whether a given time series is distinguishable from any well-defined process including deterministic chaos. In this report we present fundamental concerns with respect to the above claims (Grigorov, 2006) in a systematic manner with simple examples. The discussion provided especially discourages the choice of SSA for inferring nonlinear dynamical structure form time series obtained in any biological paradigm.Comment: 6 pages, 2 figure

    Estimation of stability derivatives and dynamic stability characteristics of basic and AEW HS-748 aircraft

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    Longitudinal and lateral stability derivatives of the basic and the AEW configurations of the HS-748 aircraft have been estimated. DATCOM and ESDU Data Sheet methods were employed to estimate the complete set of derivatives of the basic aircraft. Derivatives of the AEW aircraft were obtained by a judicious use of some of the measured static wind-tunnel force and moment data in the estimation scheme. Stick-fixed and stick-free dynamic stability characteristics of the basic and the AEW aircraft were computed using the estimated stability derivatives for a range of values of the aircraft weight and C.G. location. The dynamic stability characteristics are expressed in terms of the period, damping and time-to-half amplitude of the different modes of longitudinal and lateral motions. Both the basic and the AEW aircraft are found to be stable in all modes except the spiral mode, which exhibits a mild divergence. Damping of the lateral oscillatory mode with rudder-free, although positive, is rather low for both the basic and the AEW configurations. In general, installation of rotodome reduces the effectiveness of horizontal and vertical stabilizers and also the control effectiveness of the elevator and rudder, but it does not cause any major qualitative changes In the dynamic stability characteristics of the aircraft

    Interaction of NH3_3 gas on α\alpha-MoO3_3 nanostructures - a DFT investigation

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    The structural stability, electronic properties and NH3_3 adsorption properties of pristine, Ti, Zr and F substituted α\alpha-MoO3_3 nanostructures are successfully studied using density functional theory with B3LYP/LanL2DZ basis set. The structural stability of α\alpha-MoO3_3 nanostructures is discussed in terms of formation energy. The electronic properties of pristine, Ti, Zr and F incorporated α\alpha-MoO3_3 nanostructures are discussed in terms of HOMO-LUMO gap, ionization potential and electron affinity. α\alpha-MoO3_3 nanostructures can be fine-tuned with suitable substitution impurity to improve the adsorption characteristics of ammonia, which can be used to detect NH3_3 in a mixed environment. The present work gives an insight into tailoring α\alpha-MoO3_3 nanostructures for NH3_3 detection.Comment: 16 pages, 20 figures, 2 table

    Lucas Graceful Labeling for Some Graphs

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    By a graph, we mean a finite undirected graph without loops or multiple edges
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