56 research outputs found
Development of a universal spot weld model for automotive FEM crash simulations
This thesis deals with the finite element simulation of spot welded joint in crash analysis. Spot welding is a very common joining process in the automotive industry. It is cost effective and it provides a very fast production rate of automotive body components. Despite this advantage, spot welds are very susceptible to various types of loading conditions. Therefore they are prone to failure, if not designed properly, during their service life time. Therefore it is very important to understand the behaviour of spot welds and their failure characteristics. Generally, before the manufacturing stage, most of the automotive structural components are designed and tested in a virtual design environment. It is important to examine the crashworthiness of these body-in-white structures. To asses the crashworthiness of these structures they need to be represented correctly in virtual simulations, which necessitate the development of spot welded joint models to be included in crash analysis. Usually the models for the body-in-white structures are complicated and huge, which contains thousands of spot welded joints. Therefore a simple model for spot welded joints is desirable. Six different spot welded joint models were developed in this thesis to serve the above mentioned purpose. At the same time the simplicity issue of these developed spot weld models were also addressed, so that they can be integrated easily in a large assembly system, which consists of thousands of spot welded joints. Moreover for an effective modelling strategy, the computational costs incurred by the adopted spot weld models need also to be taken into consideration. Therefore the approach undertaken in this thesis was to study the characteristics of only one spot welded joint on a test coupon with the developed suitable spot weld nugget modelling configurations
Development of a Low Cost MQL Setup for Turning Operations
In this study, the effect of MQL application on the tool wear, surface roughness and chip formation in turning Aluminum alloy 6061 is investigated. Experiments were carried out by plain turning of an Aluminum bar with varying depth of cut, cutting speeds (spindle speed) and cutting environments (Dry, Wet and MQL). A newly designed, cost efficient and portable MQL setup was developed for this study. For each experimental trial, five passes were carried out in order to promote the formation of tool wear. After each pass, the tool surface was examined under a microscope and the surface roughness was measured using a stylus based surface tester. The extent of tool wear from each pass is measured by using ImageJ software. Chips were collected after the five passes and were physically examined. The newly designed MQL delivery system was successful in delivering a fine mist of lubricant at the cutting point. MQL lubrication provided lower surface roughness and tool wear values compared to wet and dry conditions due to effective temperature reduction and improved lubrication penetration of cutting zones, as well as better chip flushing. Chip formed under MQL conditions had reduced chip thickness due to reduced temperatures. MQL was found to have the greatest positive impact on tool wear and surface roughness parameters based on ANOVA results
Effect of ovarian types and collection techniques on the number of follicles and the quality of cumulus-oocyte-complexes in cow
This experiment was conducted for evaluation of bovine slaughterhouse ovary, follicles, and cumulus-oocyte-complexes (COCs) and to compare the effect of collection techniques on the recovery rate of COCs. The collected slaughterhouse ovaries was classified as corpus luteum present (CL+) and corpus luteum absent (CL-) groups. It was found that 62.5% of the ovaries collected were CL- type and 37.5% were CL+ type. For collection of COCs, blunt dissection and aspiration techniques were performed and number of follicles collected was recorded. The higher number of follicles were dissected and aspirated from CL - ovaries (11.2±1.8and 37.8±14.9, respectively) compared to CL+ ovaries 10.5±1.5and 28.3±15.6, respectively). The follicular materials collected from both techniques were observed under microscope to categorize the COCs as A (oocyte surrounded with cumulous cells homogenously), B (oocyte surrounded with cumulous cells partially), C (oocyte not surrounded at all by cumulous cells) and D (degeneration observed both in oocyte and cumulous cells). Grade A and grade B were classified as normal and grade C and grade D were considered as abnormal COCs. The result indicated that ovaries having no CL contributing more total number of COCs per ovary (6.8±1.0) and also contributing higher normal COCs (5.7±0.9) than that of ovaries with CL (6.0±2.0 and 4.5±1.5, respectively) in blunt dissection technique. But same trend of result was not found in aspiration technique. Similarly, higher percentage of COCs recovery rate was also recorded in blunt dissection (61.6±4.6% vs 16.5±4.9%, on total basis) than aspiration (48.6±2.9% vs 11.7±4.1%, on normal basis) technique. So, ovaries without CL and blunt dissection technique found more suitable for harvesting the higher number and superior quality of COCs for extending the in vitro embryo production experiment. Bang. J. Anim. Sci. 2016. 45 (3): 10-1
Finite element simulation of mechanical properties of graphene sheets
© Published under licence by IOP Publishing Ltd. Graphene is the material for the twenty first century applications. In this paper, the elastic properties of monolayer and double layer Graphene sheets, typically less than 10nm in size are investigated through linear finite element simulations. The effect of aspect ratio, sizes and chirality of the Graphene sheet on the Young's modulus, Shear modulus and Poisson's ratio are studied. By using structural mechanics approach combining atomistic and equivalent continuum techniques, the Young's modulus, shear modulus and the Poisson ratio were found and they slightly increase with the aspect ratio but decrease with the size of the Graphene sheet. These simulated properties compliment the mechanical properties of Graphene found in literature
Animal models of chemotherapy-induced peripheral neuropathy:a machine-assisted systematic review and meta-analysis
<div><p>We report a systematic review and meta-analysis of research using animal models of chemotherapy-induced peripheral neuropathy (CIPN). We systematically searched 5 online databases in September 2012 and updated the search in November 2015 using machine learning and text mining to reduce the screening for inclusion workload and improve accuracy. For each comparison, we calculated a standardised mean difference (SMD) effect size, and then combined effects in a random-effects meta-analysis. We assessed the impact of study design factors and reporting of measures to reduce risks of bias. We present power analyses for the most frequently reported behavioural tests; 337 publications were included. Most studies (84%) used male animals only. The most frequently reported outcome measure was evoked limb withdrawal in response to mechanical monofilaments. There was modest reporting of measures to reduce risks of bias. The number of animals required to obtain 80% power with a significance level of 0.05 varied substantially across behavioural tests. In this comprehensive summary of the use of animal models of CIPN, we have identified areas in which the value of preclinical CIPN studies might be increased. Using both sexes of animals in the modelling of CIPN, ensuring that outcome measures align with those most relevant in the clinic, and the animal’s pain contextualised ethology will likely improve external validity. Measures to reduce risk of bias should be employed to increase the internal validity of studies. Different outcome measures have different statistical power, and this can refine our approaches in the modelling of CIPN.</p></div
Animal models of chemotherapy-induced peripheral neuropathy: A machine-assisted systematic review and meta-analysis
We report a systematic review and meta-analysis of research using animal models of chemotherapy-induced peripheral neuropathy (CIPN). We systematically searched 5 online databases in September 2012 and updated the search in November 2015 using machine learning and text mining to reduce the screening for inclusion workload and improve accuracy. For each comparison, we calculated a standardised mean difference (SMD) effect size, and then combined effects in a random-effects meta-analysis. We assessed the impact of study design factors and reporting of measures to reduce risks of bias. We present power analyses for the most frequently reported behavioural tests; 337 publications were included. Most studies (84%) used male animals only. The most frequently reported outcome measure was evoked limb withdrawal in response to mechanical monofilaments. There was modest reporting of measures to reduce risks of bias. The number of animals required to obtain 80% power with a significance level of 0.05 varied substantially across behavioural tests. In this comprehensive summary of the use of animal models of CIPN, we have identified areas in which the value of preclinical CIPN studies might be increased. Using both sexes of animals in the modelling of CIPN, ensuring that outcome measures align with those most relevant in the clinic, and the animal's pain contextualised ethology will likely improve external validity. Measures to reduce risk of bias should be employed to increase the internal validity of studies. Different outcome measures have different statistical power, and this can refine our approaches in the modelling of CIPN
Prevalence of self-reported tuberculosis, knowledge about tuberculosis transmission and its determinants among adults in India: results from a nation-wide cross-sectional household survey
Electrocardiogram Pattern Recognition and Analysis Based on Artificial Neural Networks and Support Vector Machines: A Review
Tensile strength and failure simulation of simplified spot weld models
A simple model for spot weld joints is desirable in body-in-white automotive structures which contains thousands of them. Hence, comparative performance and failure prediction study of six simplified spot weld models in terms of their geometric and constitutive properties are presented in this paper. The stiffness characteristics of these models under tensile loading condition were compared with the experimental results. It was found that the current spot weld modelling practice in the automotive industry predict the strength with 45.33% of error. To simulate the joint failure a material damage criterion correlating ultimate tensile strength of material was implemented in the developed models. The comparative study with respect to the accuracy was also related with the computational cost incurred by the different models. Hence, suitable modelling conditions to design a finite element model for spot welded joints are established which is very simple to develop, relatively cheap in terms of computational costs but yet predicts reasonably accurate results
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