19 research outputs found
Leishmaniosi viscerale e cutanea in ambito familiare. Problematiche cliniche e terapeutiche
Mathematical modeling and simulation of soluble protein extraction during leaching process in surimi elaboration
This work presents a mathematical model to simulate the extraction process of soluble protein from sábalo (Prochilodus platensis) during the surimi elaboration. The mathematical model consists of both partial differential and algebraic equations. Central finite difference method and the explicit scheme were applied to discretize the partial differential equation. The resulting model was implemented into the optimization environment General Algebraic Modeling System (GAMS). Experimental data obtained from laboratory scale using sábalo as raw material, was used to verify the output results of the proposed model. A good agreement between experimental and simulated extraction yields was obtained (R2 = 0.9552). Once validated, the model was used to investigate the influence of several parameters such as, particle?s diameter, volume fraction of the solvent, residence time and agitation velocity on the extraction efficiency. The results are presented and discussed through different case studies.Fil: Reinheimer, Maria Agustina. Universidad Tecnologica Nacional. Regional Rosario. Centro de Aplicaciones Informaticas y Modelado En Ingenieria; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; ArgentinaFil: Medina, J. R.. Universidad Nacional del Litoral. Facultad de IngenierĂa QuĂmica; ArgentinaFil: Scenna, Nicolas Jose. Universidad Tecnologica Nacional. Regional Rosario. Centro de Aplicaciones Informaticas y Modelado En Ingenieria; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; ArgentinaFil: Mussati, Sergio Fabian. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Santa Fe. Instituto de Desarrollo y Diseño (i); Argentina. Universidad Tecnologica Nacional. Regional Rosario. Centro de Aplicaciones Informaticas y Modelado En Ingenieria; ArgentinaFil: Freyre, M.. Universidad Nacional del Litoral. Facultad de IngenierĂa QuĂmica; ArgentinaFil: Perez, Gustavo Alberto. Universidad Nacional del Litoral. Facultad de IngenierĂa QuĂmica; Argentin
Conceptual design and simulation tools applied to the evolutionary optimization of a bioethanol purification plant
We present an evolutionary optimization procedure applied to the design and simulation of the unit operations in a bioethanol purification plant. Conceptual and rigorous models are used; the first are utilized to determine initial values for design and operating variables, and then rigorous simulation is used to refine the results. The use of rigorous models allows for the elimination of simplifying assumptions, the interconnection of equipment, and the calculation of the operating and investment costs. Once an initial design of the purification plant is obtained, opportunities of improvement are easily recognized and then tested by performing the design and simulation steps until a cost-effective bioethanol purification plant is achieved. The methodology is applied to the purification process for a feed leaving the fermentation step of a conventional corn dry-grind processing facility producing 24 million L/year of ethanol and 19 million kg/year of distiller's dry grains with solubles (DDGS). The feed to the purification plant (22 170 kg/h) is mainly composed by ethanol (10.80% w/w) and water (88.98% w/w) with traces of methanol (0.0226% w/w) and fusel (0.2009% w/w). Following the proposed approach, two initial designs of the whole purification plant using different technologies to break the azeotrope between ethanol and water are compared in terms of operating and investment costs. Savings in overall costs of about 32% are achieved by the alternative distillation/pervaporation in comparison with the option distillation/extractive distillation. Then, the membrane-based technology is adopted as the core of the purification process and a search for further improvements is performed. Four alternative designs were evaluated. In each case, the steam consumption of the evaporation sector is reduced by 1 300 kg/h by condensing the ethanol-rich side stream from the main rectification column in the first effect of the train. Finally, the option characterized by an ethanol composition in the ethanol-rich side stream of 91.24% w/w is selected as the quasi-optimal design because overall costs are reduced by 6.67% with respect to the base case and by 11.48% with respect to the worst case analyzed.Fil: Hoch, Patricia Monica. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Planta Piloto de IngenierĂa QuĂmica. Universidad Nacional del Sur. Planta Piloto de IngenierĂa QuĂmica; ArgentinaFil: Espinosa, Hector Jose Maria. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Santa Fe. Instituto de Desarrollo y Diseño. Universidad TecnolĂłgica Nacional. Facultad Regional Santa Fe. Instituto de Desarrollo y Diseño; Argentin