Instituting an undergraduate core clerkship in radiology: initial experiences in Pakistan

Utilization of radiology as an educational resource carries great potential. Accreditation bodies, physicians and medical students deem it important for a well rounded medical curriculum. Unfortunately this resource is yet to be developed and implemented to an optimal extent. We share the experiences from the first radiology core clerkship in Pakistan at the undergraduate level. An overview of clerkship objectives and structure is followed by discussion on lessons learnt during the initial three years of institution. Development of assessable objectives, integration of radiology with other specialties, and supervised andragogical learning tailored for undergraduate students are emphasized

Faculty and patient evaluations of radiology residents\u27 communication and interpersonal skills

Objective: To assess communication and interpersonal skills (CIS) of radiology residents through faculty and standardised patients (SP). Methods: In this day-long objective structured clinical examination (OSCE) in January 2009, 42 radiology residents took part at six stations in Karachi, each with a standardised patient and a faculty evaluator. Each encounter lasted 15 minutes followed by independent assessments of the residents by both the evaluators. Results: Based on rating-scale evaluations, all cases had satisfactory internal consistency (Cronbach\\u27s alpha 0.6 to 0.9). The alpha values were comparatively diminutive against the checklist scores. Correlation among faculty was 0.6 (p Conclusion: Both checklists and rating scales can serve as satisfactory assessment tools for communication and interpersonal skills using objective structured and clinical examination with the assistance of faculty and standardised patients

Pharmacognostic Studies of Some Indigenous Medicinal Plants of Pakistan

Medicinal plants constitute an effective source of traditional and modern medicines. The plant is a biosynthetic laboratory, not only for chemical compounds but also a multitude of the compounds. The present research work was confined to study the macro, microscopic features and analysis of powdered drug of Acacia modesta Wall., Acacia nilotica (L.) Delile, Berberis lycium Royle and Zanthoxylum alatum D. C. Prod. These studies were carried out in Botany laboratory of University of Arid Agriculture, Rawalpindi during 2004. These species are used as miswak (tooth brush) by local people of Pakistan in different areas. Anatomical features such as, fibres, parenchyma cells, vessels and pith were identified during microscopic studies. Powdered miswak of Acacia modesta Wall., Berberis lycium Royle and Zanthoxylum alatum D. C. Prod. were soluble in sulphuric acid only while insoluble in other solvents i.e., hydrochloric acid, acetic acid, benzene and water. Powdered miswak of Acacia nilotica was insoluble in these solvents. Powdered drug of these species did not retain their original colour in cold and hot tests and on dry filter paper, when mixed in various solvents

Cerebral deep venous thrombosis: case report and literature review

The case of a 28 years old woman presenting with headache, drowsiness and vomiting of a short duration, is presented. She was diagnosed as deep cerebral venous thrombosis on the basis of MRI findings. Treatment with heparin gave completed recovery

Barriers in surgical research: A perspective from the developing world

Research in surgery has led to significant advances over the last century in terms of how medicine is practised in and outside the operating rooms today. Surgical research in the developed countries is responsible for most of this advancement, but it is often inapplicable in resource-limited settings in the developing world. Lower- and middle-income countries are in a unique position to take this work further, but they are limited by certain barriers. These barriers could broadly be classified under social and cultural, infrastructure, financial, ethical, and personal categories. These barriers are often not fully realised, but can potentially be addressed with concerted efforts to continue the advancement of medicine for everyone

Industrial Air Emission Pollution: Potential Sources and Sustainable Mitigation

Air of cities especially in the developing parts of the world is turning into a serious environmental interest. The air pollution is because of a complex interaction of dispersion and emission of toxic pollutants from manufactories. Air pollution caused due to the introduction of dust particles, gases, and smoke into the atmosphere exceeds the air quality levels. Air pollutants are the precursor of photochemical smog and acid rain that causes the asthmatic problems leading into serious illness of lung cancer, depletes the stratospheric ozone, and contributes in global warming. In the present industrial economy era, air pollution is an unavoidable product that cannot be completely removed but stern actions can reduce it. Pollution can be reduced through collective as well as individual contributions. There are multiple sources of air pollution, which are industries, fossil fuels, agro waste, and vehicular emissions. Industrial processes upgradation, energy efficiency, agricultural waste burning control, and fuel conversion are important aspects to reducing pollutants which create the industrial air pollution. Mitigations are necessary to reduce the threat of air pollution using the various applicable technologies like CO2 sequestering, industrial energy efficiency, improving the combustion processes of the vehicular engines, and reducing the gas production from agriculture cultivations

Hamltonian Connectedness and Toeplitz Graphs

A square matrix of order n is called Toeplitz matrix if it has constant elements along all diagonals parallel to the main diagonal and a graph is called Toeplitz graph if its adjacency matrix is Toeplitz. In this paper we proved that the Toeplitz graphs , for   and  are Hamiltonian  connected

Human Cryptosporidiosis: An insight into Epidemiology, Modern Diagnostic Tools and Recent Drug Discoveries

Cryptosporidiosis is an emerging food and water borne zoonotic disease, which is caused by genusCryptosporidium. The first Cryptosporidium spp. was isolated from mice in 1907 and gained importance when it was found in an HIV positive patient. It usually causes self-limiting diarrhea in young children and immunocompetent patients. However, it may lead to chronic diarrhea with life threatening condition in immunocompromised patients. Other complications related to this transmittable infection may include respiratory problems, skin rashes and headache. HIV/AIDS patients are highly susceptible host for this parasite. Cryptosporidium parvum and Cryptosporidium hominis are the known pathogenic species, prevalent among humans and they are being transmitted through contaminated food and water. Usually, the diagnosis of Cryptosporidium spp. is dependent on microscopic technique in many countries, which has a low sensitivity and specificity leading to false positive results. However, for a step forward to successful epidemiological studies, advanced techniques (Serological and DNA-based) provide us the better ways of diagnosis with more sensitivity and specificity. Furthermore, no antiparasitic drug has found to be effective againstCryptosporidium spp. except Nitazoxanide which is FDA-approved and effective only when administered along with antiretroviral therapy. In this regard, present review summarizes the various epidemiological studies conducted around the globe along with modern diagnostic tools and the suitable treatment available now a days. This systemized review will help the scientists to better understand all the aspects of cryptosporidiosis at one platform which may help in designing surveillance studies through selection of sensitive diagnostic techniques. The new drugs mentioned in this review may also help to better control this parasite in humans, especially immunocompromised individuals

Nanodiagnosis and Nanotreatment of Cardiovascular Diseases: An Overview

Cardiovascular diseases (CVDs) are the world’s leading cause of mortality and represent a large contributor to the costs of medical care. Although tremendous progress has been made for the diagnosis of CVDs, there is an important need for more effective early diagnosis and the design of novel diagnostic methods. The diagnosis of CVDs generally relies on signs and symptoms depending on molecular imaging (MI) or on CVD-associated biomarkers. For early-stage CVDs, however, the reliability, specificity, and accuracy of the analysis is still problematic. Because of their unique chemical and physical properties, nanomaterial systems have been recognized as potential candidates to enhance the functional use of diagnostic instruments. Nanomaterials such as gold nanoparticles, carbon nanotubes, quantum dots, lipids, and polymeric nanoparticles represent novel sources to target CVDs. The special properties of nanomaterials including surface energy and topographies actively enhance the cellular response within CVDs. The availability of newly advanced techniques in nanomaterial science opens new avenues for the targeting of CVDs. The successful application of nanomaterials for CVDs needs a detailed understanding of both the disease and targeting moieties