Bioethical problems of diametric opposites-vaccine prevention and anti-vaccination movement

The article discusses possible bioethical problems of opposing points of view: supporters and opponents of vaccination, the view of "anti-vaccination" as a direction of dissidence, and questions of the law and ethics of vaccinationВ статье рассматриваются возможные биоэтические проблемы противоборствующих точек зрения: сторонников и противников прививок, взгляд на «антивакцинаторство» как направление диссидентства и вопросы права и этики вакцинаци

Epidemiological features of the incidence of pertussis infection in the territory of Krasnoturinsk

The aim of the study – is to determine the epidemiological features of pertussis infection in the territory of KrasnoturinskЦель исследования – определить эпидемиологические особенности коклюшной инфекции на территории ГО Краснотурьинс

Whooping cough in the Sverdlovsk region. Methodological approaches to the effective oversight of the infection in real time

The paper presents the epidemiological features of whooping cough in the Sverdlovsk region in the period from 1995 to 2018. The characteristic of the epidemic process of whooping cough is given, the main age and social risk groups for morbidity are determined, the effectiveness of vaccine prevention of this infection is assessed. The data obtained allow us to consider immunization against pertussis as the main component of the control of pertussis infection, however, methodological support of immunoprophylaxis of this infection at the present stage requires optimization.В работе представлены эпидемиологические особенности коклюша на территории Свердловской области в период с 1995 по 2018 гг. Дана характеристика эпидемического процесса коклюша, определены основные возрастные и социальные группы риска по заболеваемости, проведена оценка эффективности вакцинопрофилактики этой инфекции. Полученные данные позволяют рассматривать иммунизацию против коклюша как основную составляющую контроля коклюшной инфекции, однако методическое обеспечение иммунопрофилактики этой инфекции на современном этапе требует оптимизаци

Epidemiological features of whooping cough in a large area of Yekaterinburg

The purpose of the study is to study the epidemiological features of pertussis infection at the present stage to determine the key directions for improving the epidemiological surveillance system.Цель исследования – изучить эпидемиологические особенности коклюшной инфекции на современном этапе для определения ключевых направлений совершенствования системы эпидемиологического надзора

Mineralogy and geochemistry of triassic carbonatites in the Matcha alkaline intrusive complex (Turkestan-Alai Ridge, Kyrgyz Southern Tien Shan), SW Central Asian orogenic belt

Postorogenic intrusions of essexites and alkaline and nepheline syenites in the Turkestan-Alai segment of the Kyrgyz Southern Tien Shan coexist with dikes and veins of carbonatites dated at ∼220 Ma by the Ar–Ar and Rb–Sr age methods. They are mainly composed of calcite and dolomite (60–85%), as well as sodic amphibole, phlogopite, clinopyroxene, microcline, albite, apatite, and magnetite, with accessory niobate, ilmenite, Nb-rutile, titanite, zircon, baddeleyite, monazite-(Ce), barite, and sulfides. The rocks share mineralogical and geochemical similarity with carbonatites that originated by liquid immiscibility at high temperatures above 500 °C. Alkaline silicate and salt-carbonate melts are derived from sources with mainly negative bulk εNd(t) ∼ from −11 to 0 and high initial 87Sr/86Sr ratios (∼0.7061–0.7095) which may be due to mixing of PREMA and EM−type mantle material. Pb isotopic ratios in accessory pyrrhotite (206Pb/204Pb = 18.38; 207Pb/204Pb = 15.64; 208Pb/204Pb = 38.41) exhibit an EM2 trend. The intrusions bear signatures of significant crustal contamination as a result of magma genesis by syntexis and hybridism. Concordant isotope composition changes of δ13C (−6.5 to −1.9‰), δ18O (9.2–23‰), δD (−58 to −41‰), and δ34S (12.6–12.8‰) in minerals and rocks indicate inputs of crustal material at the stage of melting and effect of hot fluids released during dehydration of metamorphosed oceanic basalts or sediments. The observed HFSE patterns of the oldest alkaline gabbro may be due to interaction of the primary mafic magma with IAB-type material. The isotope similarity of alkaline rocks with spatially proximal basalts of the Tarim large igneous province does not contradict the evolution of the Turkestan-Alai Triassic magmatism as the “last echo” of the Tarim mantle plume

Mineralogy and geochemistry of triassic carbonatites in the Matcha alkaline intrusive complex (Turkestan-Alai Ridge, Kyrgyz Southern Tien Shan), SW Central Asian orogenic belt

Postorogenic intrusions of essexites and alkaline and nepheline syenites in the Turkestan-Alai segment of the Kyrgyz Southern Tien Shan coexist with dikes and veins of carbonatites dated at ∼220 Ma by the Ar–Ar and Rb–Sr age methods. They are mainly composed of calcite and dolomite (60–85%), as well as sodic amphibole, phlogopite, clinopyroxene, microcline, albite, apatite, and magnetite, with accessory niobate, ilmenite, Nb-rutile, titanite, zircon, baddeleyite, monazite-(Ce), barite, and sulfides. The rocks share mineralogical and geochemical similarity with carbonatites that originated by liquid immiscibility at high temperatures above 500 °C. Alkaline silicate and salt-carbonate melts are derived from sources with mainly negative bulk εNd(t) ∼ from −11 to 0 and high initial 87Sr/86Sr ratios (∼0.7061–0.7095) which may be due to mixing of PREMA and EM−type mantle material. Pb isotopic ratios in accessory pyrrhotite (206Pb/204Pb = 18.38; 207Pb/204Pb = 15.64; 208Pb/204Pb = 38.41) exhibit an EM2 trend. The intrusions bear signatures of significant crustal contamination as a result of magma genesis by syntexis and hybridism. Concordant isotope composition changes of δ13C (−6.5 to −1.9‰), δ18O (9.2–23‰), δD (−58 to −41‰), and δ34S (12.6–12.8‰) in minerals and rocks indicate inputs of crustal material at the stage of melting and effect of hot fluids released during dehydration of metamorphosed oceanic basalts or sediments. The observed HFSE patterns of the oldest alkaline gabbro may be due to interaction of the primary mafic magma with IAB-type material. The isotope similarity of alkaline rocks with spatially proximal basalts of the Tarim large igneous province does not contradict the evolution of the Turkestan-Alai Triassic magmatism as the “last echo” of the Tarim mantle plume

Dissecting aortic aneurysm in a young woman

We present a case of thoracic aortic dissection in a 33-year-old woman. The diagnosis was difficult, and the right diagnosis was made 4 months after the initial clinical manifestation. Aortic dissection was caused by necrosis of the media combined with longstanding arterial hypertension. Surgical intervention was performed timely and was effective