156 research outputs found
Determination Suitable Strategies of Educational Services Universial Jihad to Gain Increase Competing Advantage
Today world is changing fast and moving toward evolution and development has become an individual, social, national and global demand. Therefore economical, cultural, educational tendency to education. Exchange of ideas and providing new finding are increased as well as these actives. shomal unit universial <<jihad>>[1] organization have to improve their performance and efficiency to survive and preserve their competing advantages against internal and external antagonists and they can’t do this without identifying internal and external factors and suitable strategic planning . strategic planning is the process of a long term program to navigate the organization toward a specified goal in this paper, we used a comprehensive frame of setting strategy to set the strategy of the organization, with considering to the investigation of internal (strength and weaknesses), and external (opportunities and threats) and combined strategies by swot model, try to provide suitable strategies by swot model, try to provide suitable strategies for universial jihad. Then we assessed and evaluate the provide strategies by quantitative strategy planning matrix. (QSPM
Determination Suitable Strategies of Educational Services Universial Jihad to Gain Increase Competing Advantage
Today world is changing fast and moving toward evolution and development has become an individual, social, national and global demand. Therefore economical, cultural, educational tendency to education. Exchange of ideas and providing new finding are increased as well as these actives. shomal unit universial <<jihad>>[1] organization have to improve their performance and efficiency to survive and preserve their competing advantages against internal and external antagonists and they can’t do this without identifying internal and external factors and suitable strategic planning . strategic planning is the process of a long term program to navigate the organization toward a specified goal in this paper, we used a comprehensive frame of setting strategy to set the strategy of the organization, with considering to the investigation of internal (strength and weaknesses), and external (opportunities and threats) and combined strategies by swot model, try to provide suitable strategies by swot model, try to provide suitable strategies for universial jihad. Then we assessed and evaluate the provide strategies by quantitative strategy planning matrix. (QSPM
Determination Suitable Strategies of Educational Services Universial Jihad to Gain Increase Competing Advantage
Today world is changing fast and moving toward evolution and development has become an individual, social, national and global demand. Therefore economical, cultural, educational tendency to education. Exchange of ideas and providing new finding are increased as well as these actives. shomal unit universial <<jihad>>[1] organization have to improve their performance and efficiency to survive and preserve their competing advantages against internal and external antagonists and they can’t do this without identifying internal and external factors and suitable strategic planning . strategic planning is the process of a long term program to navigate the organization toward a specified goal in this paper, we used a comprehensive frame of setting strategy to set the strategy of the organization, with considering to the investigation of internal (strength and weaknesses), and external (opportunities and threats) and combined strategies by swot model, try to provide suitable strategies by swot model, try to provide suitable strategies for universial jihad. Then we assessed and evaluate the provide strategies by quantitative strategy planning matrix. (QSPM
Data Censoring with Set-Membership Affine Projection Algorithm
In this paper, the set-membership affine projection (SM-AP) algorithm is utilized to censor non-informative data in big data applications. To this end, the probability distribution of the additive noise signal and the excess of the mean-squared error (EMSE) in steady-state are employed in order to estimate the threshold parameter of the single threshold SM-AP (ST-SM-AP) algorithm aiming at attaining the desired update rate. Furthermore, by defining an acceptable range for the error signal, the double threshold SM-AP (DT-SM-AP) algorithm is proposed to detect very large errors due to the irrelevant data such as outliers. The DT-SM-AP algorithm can censor non-informative and irrelevant data in big data applications, and it can improve the misalignment and convergence rate of the learning process with high computational efficiency. The simulation and numerical results corroborate the superiority of the proposed algorithms over traditional algorithms
Corrigendum to “The effectiveness of counseling based on acceptance and commitment therapy on body image and self-esteem in polycystic ovary syndrome: An RCT” [Int J Reprod BioMed 2020; 18: 243–252]
This is a Corrigendum to “The effectiveness of counseling based on acceptance and commitment therapy on body image and self-esteem in polycystic ovary syndrome: An RCT” [Int J Reprod BioMed 2020; 18: 243–252]
The effectiveness of counseling based on acceptance and commitment therapy on body image and self-esteem in polycystic ovary syndrome: An RCT
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders known with irregular menstruation, hirsutism, alopecia, obesity, infertility, and acne. These symptoms cause a negative effect on the satisfaction of body image, self-esteem, and quality of life in such patients. Recent studies emphasize the need to consider the psychological problems in these women and also the need for appropriate interventions.
Objective: The aim of this study was to determine the effectiveness of group counseling based on acceptance and commitment therapy (ACT) on body image and self-esteem in patients with PCOS.
Materials and Methods: In this randomized controlled trial, 52 women with PCOS were randomly allocated to intervention and control groups (n = 26/each) using the table of random numbers. Group counseling based on the ACT was held in eight sessions of 90 min once a week for the intervention group. The demographic questionnaire, Littleton development of the body image concern inventory and Rosenberg self-esteem scale were completed in both groups before, immediately after, and one month after the intervention.
Results: The mean scores of body image concern (p = 0.001) and self-esteem (p ≤ 0.001) in the intervention group after the intervention and follow-up were significantly different from the control group.
Conclusion: Based on the findings of this study, use of cognitive-behavioral therapies in health care centers is recommended as a complementary method.
Key words: Acceptance and commitment therapy, Body image, Self-esteem, Polycystic ovary syndrome, Cognitive behavior therapies
Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research
Induced pluripotent stem cells (iPSCs) exhibit an unlimited ability to self-renew and produce various differentiated cell types, thereby creating high hopes for both scientists and patients as a great tool for basic research as well as for regenerative medicine purposes. The availability and safety of iPSCs for therapeutic purposes require safe and highly efficient methods for production of these cells. Different methods have been used to produce iPSCs, each of which has advantages and disadvantages. Studying these methods would be very helpful in developing an easy, safe, and efficient method for the generation of iPSCs. Since iPSCs can be generated from somatic cells, they can be considered as valuable cellular resources available for important research needs and various therapeutic purposes. Coronavirus disease 2019 (COVID-19) is a disease that has endangered numerous human lives worldwide and currently has no definitive cure. Therefore, researchers have been rigorously studying and examining all aspects of COVID-19 and potential treatment modalities and various drugs in order to enable the treatment, control, and prevention of COVID-19. iPSCs have become one of the most attractive and promising tools in this field by providing the ability to study COVID-19 and the effectiveness of drugs on this disease outside the human body. In this study, we discuss the different methods of generation of iPSCs as well as their respective advantages and disadvantages. We also present recent applications of iPSCs in the study and treatment of COVID-19
A Stereological and Biochemical Examination: Hepatoprotective Activity of Anthemis odontostephana Boiss. Ethanol Extract Against CCl4-Induced Hepatotoxicity in Mice
Background and objectives: In Iranian traditional medicine, Anthemis odontostephana Boiss has been used in treating gastric ulcers, diabetes, and inflammatory diseases. In the present study, hepatoprotective activity of A. odontostephana ethanol extract (AOEE) on carbon tetrachloride (CCl4)-induced hepatotoxicity in male mice has been evaluated. Methods: In the present experimental study, Sixty male mice were divided into six groups (n=10); Group I was considered as control, received 1 mL/kg olive oil intraperitoneally and 0.5 mL distilled water through gavage. Group II was considered as untreated group, received 1 mg/kg CCl4 mixed with olive oil in the ratio of 1:1, intraperitoneally and 0.5 mL distilled water orally. Group III, IV, V and VI received CCl4 mixed with olive oil in the ratio of 1:1 intraperitoneally and 20, 40, 80 and 160 mg/kg of AOEE through gavage for 45 continuous days. On the last day, the animals of all groups were euthanized and blood and liver were collected for assessing biochemical and histological parameters. The data were analyzed using one-way ANOVA and post-hoc Duncan’s tests. Results: Different doses of AOEE (especially AOEE160) could significantly (pConclusion: According to the obtained results, AOEE can regulate the biochemical parameters and inhibits hepatic damages in CCl4-induced hepatotoxicity in mice
The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017 : a systematic analysis for the Global Burden of Disease study 2017
Background: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. Methods: Estimates from GBD 2017 were used to analyse the incidence, mortality, and DALYs due to stomach cancer at the global, regional, and national levels. The rates were standardised to the GBD world population and reported per 100 000 population as age-standardised incidence rates, age-standardised death rates, and age-standardised DALY rates. All estimates were generated with 95% uncertainty intervals (UIs). Findings: In 2017, more than 1·22 million (95% UI 1·19–1·25) incident cases of stomach cancer occurred worldwide, and nearly 865 000 people (848 000–885 000) died of stomach cancer, contributing to 19·1 million (18·7–19·6) DALYs. The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29·5, 28·2–31·0 per 100 000 population) and east Asia (28·6, 27·3–30·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. Compared with 1990, in 2017 more than 356 000 more incident cases of stomach cancer were estimated, leading to nearly 96 000 more deaths. Despite the increase in absolute numbers, the worldwide age-standardised rates of stomach cancer (incidence, deaths, and DALYs) have declined since 1990. The drop in the disease burden was associated with improved Socio-demographic Index. Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. Interpretation: Our findings provide insight into the changing burden of stomach cancer, which is useful in planning local strategies and monitoring their progress. To this end, specific local strategies should be tailored to each country's risk factor profile. Beyond the current decline in age-standardised incidence and death rates, a decrease in the absolute number of cases and deaths will be possible if the burden in east Asia, where currently almost half of the incident cases and deaths occur, is further reduced. Funding: Bill & Melinda Gates Foundation
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: A systematic analysis for the global burden of disease study 2017
© 2020 The Author(s). Background Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. Updated statistics on the incidence and mortality of oesophageal cancer, and on the disability-adjusted life-years (DALYs) caused by the disease, can assist policy makers in allocating resources for prevention, treatment, and care of oesophageal cancer. We report the latest estimates of these statistics for 195 countries and territories between 1990 and 2017, by age, sex, and Socio-demographic Index (SDI), using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD). Methods We used data from vital registration systems, vital registration-samples, verbal autopsy records, and cancer registries, combined with relevant modelling, to estimate the mortality, incidence, and burden of oesophageal cancer from 1990 to 2017. Mortality-to-incidence ratios (MIRs) were estimated and fed into a Cause of Death Ensemble model (CODEm) including risk factors. MIRs were used for mortality and non-fatal modelling. Estimates of DALYs attributable to the main risk factors of oesophageal cancer available in GBD were also calculated. The proportion of oesophageal squamous cell carcinoma to all oesophageal cancers was extracted by use of publicly available data, and its variation was examined against SDI, the Healthcare Access and Quality (HAQ) Index, and available risk factors in GBD that are specific for oesophageal squamous cell carcinoma (eg, unimproved water source and indoor air pollution) and for oesophageal adenocarcinoma (gastro-oesophageal reflux disease). Findings There were 473 000 (95% uncertainty interval [95% UI] 459 000-485 000) new cases of oesophageal cancer and 436 000 (425 000-448 000) deaths due to oesophageal cancer in 2017. Age-standardised incidence was 5.9 (5.7-6.1) per 100 000 population and age-standardised mortality was 5.5 (5.3-5.6) per 100 000. Oesophageal cancer caused 9.78 million (9.53-10.03) DALYs, with an age-standardised rate of 120 (117-123) per 100 000 population. Between 1990 and 2017, age-standardised incidence decreased by 22.0% (18.6-25.2), mortality decreased by 29.0% (25.8-32.0), and DALYs decreased by 33.4% (30.4-36.1) globally. However, as a result of population growth and ageing, the total number of new cases increased by 52.3% (45.9-58.9), from 310 000 (300 000-322 000) to 473 000 (459 000-485 000); the number of deaths increased by 40.0% (34.1-46.3), from 311 000 (301 000-323 000) to 436 000 (425 000-448 000); and total DALYs increased by 27.4% (22.1-33.1), from 7.68 million (7.42-7.97) to 9.78 million (9.53-10.03). At the national level, China had the highest number of incident cases (235 000 [223 000-246 000]), deaths (213 000 [203 000-223 000]), and DALYs (4.46 million [4.25-4.69]) in 2017. The highest national-level agestandardised incidence rates in 2017 were observed in Malawi (23.0 [19.4-26.5] per 100 000 population) and Mongolia (18.5 [16.4-20.8] per 100 000). In 2017, age-standardised incidence was 2.7 times higher, mortality 2.9 times higher, and DALYs 3.0 times higher in males than in females. In 2017, a substantial proportion of oesophageal cancer DALYs were attributable to known risk factors: tobacco smoking (39.0% [35.5-42.2]), alcohol consumption (33.8% [27.3-39.9]), high BMI (19.5% [6.3-36.0]), a diet low in fruits (19.1% [4.2-34.6]), and use of chewing tobacco (7.5% [5.2-9.6]). Countries with a low SDI and HAQ Index and high levels of indoor air pollution had a higher proportion of oesophageal squamous cell carcinoma to all oesophageal cancer cases than did countries with a high SDI and HAQ Index and with low levels of indoor air pollution. Interpretation Despite reductions in age-standardised incidence and mortality rates, oesophageal cancer remains a major cause of cancer mortality and burden across the world. Oesophageal cancer is a highly fatal disease, requiring increased primary prevention efforts and, possibly, screening in some high-risk areas. Substantial variation exists in age-standardised incidence rates across regions and countries, for reasons that are unclear
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