Asymptomatic Lone Atrial Fibrillation in Pregnant Women

We examined 43 pregnant women with paroxysms of asymptomatic lone atrial fibrillation. It was revealed that the increasing of the gestational age leads to increase of number of single, paired and group supraventricular extrasystoles; single and paired ventricular extrasystoles; number and duration of paroxysms of atrial fibrillation. However, the number of extrasystoles and paroxysms of arrhythmia decreased to baseline values after delivery. Thus, it was proved that pregnancy contributes to the increase of paroxysms of lone atrial fibrillation due to the increased influence of modulating components on the triggering extrasystoles. The importance of the method of 24-hour ECG monitoring in the detection of arrhythmia in pregnant women is emphasized. Keywords: lone atrial fibrillation, extrasystole, pregnancy

On chiral corrections to nucleon GPD

Within the pion-nucleon chiral perturbation theory we derive the leading chiral correction to the nucleon GPD at $\xi=0$. We discuss the difficulties of consideration of nonlocal light-cone operators within the theory with a heavy particle and the methods to solve the difficulties. The consideration of the chiral corrections directly for nonlocal operators allows to resolve the ambiguity of the inverse Mellin transformation. In particular, we show that the mixing between axial and vector GPDs are of order $m_\pi^2/M_N^2$, which is two orders of magnitude less that it follows from the Mellin moments calculation.Comment: 17 pages, 1 figure; minor corrections in the tex

Neurotrophins in the pathogenesis of pulmonary hypertension and right ventricular dysfunction

Pulmonary hypertension (PH) is a pathophysiological and hemodynamic condition that complicates the course of various diseases and negatively affects morbidity and mortality. The search for the new pathophysiological mechanisms for PH development and progression, the markers for predicting the PH course, and the possible targets for therapy remains relevant. This review is devoted to the role of neurotrophin (NT) system in PH pathogenesis, the possible use of NT and their receptors as a laboratory marker of its severity, and also as a potential target for influencing the pulmonary artery remodeling in PH. In addition, the participation of NTs in neoangiogenesis and restoration of nervous and muscle tissues was described

Controversial and open issues of diagnosis and treatment of myocarditis (based on the discussion of Russian national recommendations)

In October 2020, the Russian Ministry of Health approved clinical guidelines for the management of patients with myocarditis. The aim of this review was to highlight controversial and open issues without unambiguous answer or those that were not described in the paper. The review highlights the objective factors that complicate the development of practical guidelines for the management of this category of patients. Comments on the definition and classification of inflammatory heart diseases are given. The approaches to the diagnosis of patients with suspected myocarditis are discussed. Particular attention is paid to the decision-making strategy in selecting optimal therapy in patients with documented myocarditis and the role of endomyocardial biopsy

Principles of healthcare management for patients with pulmonary hypertension: focus on continuity

In managing care for patients with rare, rapidly progressive pathologies such as pulmonary hypertension (PH) and chronic thromboembolic hypertension (CTEPH), early diagnosis and speed of routing are of particular importance. Reducing the time spent on patient routing reduces the risk of disease progression, the rate of hospitalizations, and thereby the socioeconomic burden of the disease.In the Republic of Karelia, an algorithm for routing patients with PH and CTEPH has been created, which is an example of a successful healthcare management

Phytoplankton light absorption in the deep chlorophyll maximum layer of the Black Sea

© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Churilova, T., Suslin, V., Sosik, H. M., Efimova, T., Moiseeva, N., Moncheva, S., Mukhanov, V., Rylkova, O., & Krivenko, O. Phytoplankton light absorption in the deep chlorophyll maximum layer of the Black Sea. European Journal of Remote Sensing, 52, (2019): 123-136, doi: 10.1080/22797254.2018.1533389.Bio-optical data, obtained during six cruises in the Black Sea carried out during periods of seasonal stratification in years between 1996 and 2016, have been used to parametrize phytoplankton light absorption (aph(λ)) in the deep chlorophyll maximum (DCM) layer located near the bottom of euphotic zone. Relationships between aph(λ) and the sum of chlorophyll-a and phaeopigment concentrations (Chl-a) differed from those for the summertime upper mixed layer (UML). Notably, chlorophyll a specific absorption coefficients (a∗ph(λ)) were lower in the DCM and more comparable with a∗ph(λ) values typical for winter phytoplankton in the Black Sea. The aph(λ) spectral shapes in the DCM differed markedly from those in winter and in the summer UML, due to a shoulder at ~490 nm and a local maximum at ~550 nm corresponding to the absorption bands of phycourobilin and phycoerythrobilin. Light absorbing properties of phytoplankton in the DCM (amplitude and spectral shape of a∗ph(λ)) reflected physiological acclimation to local conditions on the cellular level and population shifts leading to changes in the biomass-dominant species, with Synechococcus spp. domination in the DCM. The parameterization of phytoplankton absorption in the DCM will enable refined spectral models of the downwelling radiance and primary production in the Black Sea.RAS funded this research [grant numbers АААА-А18-118020890112-1, АААА-А18-118020790229-7 and АААА-18-118012690119-7]. This work was partly supported by the Russian Foundation for Basic Research, projects [numbers 17-05-00113 and 18-45-920070]

Instructions for laboratory training in General Microbiology & Immunology for students of medical faculty

МИКРОБИОЛОГИЯАЛЛЕРГОЛОГИЯ И ИММУНОЛОГИЯЛАБОРАТОРНЫЕ РАБОТЫИНОСТРАННЫЕ СТУДЕНТЫПРАКТИЧЕСКИЕ НАВЫКИПРАКТИЧЕСКИЕ ЗАНЯТИЯИНСТРУКЦИИИММУНОЛОГИЯВ издании содержатся план, программа практических занятий и основные практические навыки по общей микробиологии и иммунологии

lifelong EDUCATION AS A FACTOR OF FORMATION OF PERSONAL TRANS-PROFESSIONALISM

The article is devoted to the consideration of the process of lifelong education as the basis for the development of personality trans-professionalism in modern conditionsСтатья посвящена рассмотрению процесса непрерывного образования как основы развития транспрофессионализма личности в современных условиях

Dynamics of endothelial function indexes in patients with post-Covid syndrome using a combination drug of ethylmethylhydroxyperidine succinate/vitamin B6

Aim: to evaluate endothelial function in patients after COVID-19 before and after treatment with combination drug of ethylmethylhydroxyperidine succinate (EMHPS)/vitamin B