13,423 research outputs found

    MiniBooNE: Status of the Booster Neutrino Experiment

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    MiniBooNE is preparing to search for nu_mu to nu_e oscillations at Fermilab. The experiment is designed to make a conclusive statement about LSND's neutrino oscillation evidence. We give a status report on the preparation of the experiment and outline the experimental prospects.Comment: 6 pages, To appear in Proceedings of the XIX International Conference on Neutrino Physics and Astrophysics (Neutrino 2000), Sudbury. Canada, 16-21 June 200

    Measuring micro-organism gas production

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    Transducer, which senses pressure buildup, is easy to assemble and use, and rate of gas produced can be measured automatically and accurately. Method can be used in research, in clinical laboratories, and for environmental pollution studies because of its ability to detect and quantify rapidly the number of gas-producing microorganisms in water, beverages, and clinical samples

    Reactivity difference between protolytic forms of some macrocyclic chromium(III) complexes in ligand substitution and electron transfer processes

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    The review provides insight into the mechanism of ligand substitution and electron transfer (from chromium( III) to iron(III)) by comparison of the reactivity of some tetraazamacrocyclic chromium(III) complexes in the conjugate acid-base forms. Use of two geometrical isomers made possible to estimate the influence of geometry and protolytic reactions in trans and cis position towards the leaving group on the rate enhancement. Studies on the reaction rates in different media demonstrated the role played by outer sphere interactions in a monodentate ligand substitution

    Cigarette smoking in men may be a risk factor for increased severity of psoriasis of the extremities

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74594/1/j.1365-2133.1996.tb03909.x.pd

    WHAT CAN A KANSAS FARMER AFFORD TO PAY TO RENT CROPLAND?

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    Five years of continuous annual data are used to measure the marginal value product of cropland (return to land) on approximately 100 Kansas farms. Determinants of the marginal value product are investigated using regression.Land Economics/Use,

    The Fabry disease-associated lipid Lyso-Gb3 enhances voltage-gated calcium currents in sensory neurons and causes pain

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    Fabry disease is an X-linked lysosomal storage disorder characterised by accumulation of glycosphingolipids, and accompanied by clinical manifestations, such as cardiac disorders, renal failure, pain and peripheral neuropathy. Globotriaosylsphingosine (lyso-Gb3), a deacylated form of globotriaosylceramide (Gb3), has emerged as a marker of Fabry disease. We investigated the link between Gb3, lyso-Gb3 and pain. Plantar administration of lyso-Gb3 or Gb3 caused mechanical allodynia in healthy mice. In vitro application of 100nM lyso-Gb3 caused uptake of extracellular calcium in 10% of sensory neurons expressing nociceptor markers, rising to 40% of neurons at 1μM, a concentration that may occur in Fabry disease patients. Peak current densities of voltage-dependent Ca(2+) channels were substantially enhanced by application of 1μM lyso-Gb3. These studies suggest a direct role for lyso-Gb3 in the sensitisation of peripheral nociceptive neurons that may provide an opportunity for therapeutic intervention in the treatment of Fabry disease-associated pain

    The healing mechanism for excited molecules near metallic surfaces

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    Radiation damage prevents the ability to obtain images from individual molecules. We suggest that this problem can be avoided for organic molecules by placing them in close proximity with a metallic surface. The molecules will then quickly dissipate any electronic excitation via their coupling to the metal surface. They may therefore be observed for a number of elastic scattering events that is sufficient to determine their structure.Comment: 4 pages, 4 figures. Added reference
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