Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.

Based on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that the benefit would be greatest in patients with a low metastatic burden. We aimed to compare standard of care for metastatic prostate cancer, with and without radiotherapy.This article is freely available via Open Access

Breastfeeding in Taiwan: a Study of Change.

Sharp declines in both the proportion of infants breastfed at all and the average age at weaning of those ever breastfed in Taiwan are documented in this dissertation. Data from a series of KAP surveys of large, nationally representative samples of married women of reproductive age define the breastfeeding experience of Taiwanese infants in 1967-1968, 1973, and 1979-1980. Parallel cross-sectional analyses are carried out in an attempt to gain underst and ing of factors influencing infant feeding practices. Breastfeeding initiation and the current status (breastfed or not at survey, by age) of children are dependent variables; analytic techniques include logit regression and life table methodologies. A context for the present research is set by extensive literature reviews on the importance of breastfeeding for infant survival and for fertility regulation in the Third World, and on existing evidence of levels and trends of breastfeeding in other developing countries.Ph.D.DemographyUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/159234/1/8304546.pd

A Qualitative Approach to Understanding Canadian Healthcare Workers’ Use of Coping Strategies during the COVID-19 Pandemic

Throughout the COVID-19 pandemic, healthcare workers (HCWs) have been exposed to highly stressful situations, including increased workloads and exposure to mortality, thus posing a risk for adverse psychological outcomes, including acute stress, moral injury, and depression or anxiety symptoms. Although several reports have sought to identify the types of coping strategies used by HCWs over the course of the pandemic (e.g., physical activity, religion/spirituality, meditation, and alcohol), it remains unclear which factors may influence HCWs’ choice of these coping strategies. Accordingly, using a qualitative approach, the purpose of the present study was to gain a deeper understanding of the factors influencing HCWs’ choice of coping strategies during the COVID-19 pandemic in Canada. Fifty-one HCWs participated in virtual, semi-structured interviews between February and June 2021. Interview transcripts were analysed through an inductive thematic approach, yielding two primary themes. First, HCWs described an ongoing shift in their approach to coping depending on their mental “bandwidth”, ranging from “quick fix” to more “intentional effort” strategies to engage in proactive strategies to improve mental health. Second, many HCWs identified various barriers to desired coping strategies during the pandemic, including the preponderance of pandemic- and other circumstantial-related barriers. The findings from this study offer a unique understanding of the factors influencing HCWs’ choice of coping strategies under novel and increased stress. This knowledge will be central to developing appropriate forms of support and resources to equip HCWs throughout and after the pandemic period, and in mitigating the potential adverse mental health impacts of this period of prolonged stress and potential trauma