Additional file 4: Table S3. of A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

DE Analysis. DE analysis results as described in “Methods,” including contrasts for c1 vs c3–5, c2 vs c3–5, c1 vs c2, and intra-c1 exposure differences. Numbers of cells in each comparison are printed above log-fold-change columns. Gene sets from Fig. 2c are included. (XLSX 3450 kb

Empirical flashover model of EHV post insulators based on ISP parameter in cold environments

The main objective of this contribution is to present an empirical model of ice-covered insulator flashover in accordance with an important flashover index, called icing stress product (ISP). The ISP as the product of the ice mass per centimeter of insulator length and the electrical conductivity of the melted ice accretion is used to establish an empirical model to determine the flashover voltage under icing conditions. To achieve this model, several tests were carried out on post station insulators typically used in Hydro-Quebec 735-kV substations, under DC and AC voltage, to determine the relationship between flashover stress and the ISP. The ISP-based method offers a good tool not only to select insulators for locations exposed to freezing conditions, but also to compare flashover results obtained under different test conditions. Moreover, to study the optimizing method of insulator flashover, the influence of air gaps on the flashover stress of ice-covered post insulators is investigated. The results reveal that the number of air gaps significantly affects the flashover stress. The test results are highly meaningful as they can be used as a reference for ranking several other insulator types and configurations in order to select the appropriate one for cold environments. Moreover, several mitigation options to improve insulator reliability in cold environments are provided

Additional file 7: of A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

AOM. Additional online materials. (PDF 243 kb

High Performance Graded Rainbow Holograms via Two-Stage Sequential Orthogonal Thiol–Click Chemistry

Orthogonal, sequential “click” reactions were implemented to yield novel polymeric substrates with the ability to record holographic data. The base-catalyzed thiol–acrylate Michael “click” reaction was implemented to yield a writable, stage 1 polymeric substrate with glass transition temperatures (<i>T</i>_g) ranging from 0 to −26 °C and rubbery storage moduli (<i>E</i>′) from 11.1 to 0.3 MPa. The loosely cross-linked matrix also contained a novel high refractive index monomer 9-(2,3-bis­(allyloxy)­propyl)-9<i>H</i>-carbazole (BAPC) that did not participate in the thiol–Michael reaction but allowed for large index gradients to be developed within the network upon subsequent exposure to coherent laser beams and initiation of the radical-mediated thiol–ene reaction. The holographic gratings were recorded with 96% diffraction efficiency and ca. 2.4 cm/mJ of light sensitivity in 2 s under a 405 nm exposure with an intensity of 20 mW/cm². Subsequent to pattern formation, via a thiol–allyl radical “click” photopolymerization initiated by flood illumination of the sample, holographic materials with high <i>T</i>_g, high modulus, diffraction efficiency as high as 82%, and refractive index modulation of 0.004 were obtained. Graded rainbow holograms that displayed colors from blue to red at a single viewing angle were readily formed through this new technique