Corrigendum

This article refers to : Parametric Kalman filter for chemical transport models. In our previous contribution Pannekoucke et al. (2016) (P16), an error has been made in the derivation of the error diffusion tensor dynamics Eq. (20). This involves an error in the Lagrangian dynamics of the uncertainty given in the Algorithm 2, while leaving the Eulerian dyanmics unchanged. The corrigendum is organized as follows. The modification of the Lagrangian dynamics is presented in Section 2, where a new version of the Algorithm 2 of P16 is presented. The computation leading to the Eulerian dynamics is described in Section 3, which gives the dynamics presented in Eq. (26) of P16

Patchwork Gridshells::Using Modularity to Facilitate Prefabrication and Simplify Construction

Modern architectural design has seen a shift towards iconic doubly-curved envelopes enclosing large column-free spaces. Gridshells have long been considered an efficient solution to such designs, but their actual use in practice has not spread worldwide. For elastic gridshells, their advantages in terms of substantial material savings can often be overshadowed by the significant challenges associated with their construction. Similarly, for rigid gridshells, the manufacture of a large number of different members and nodal connections is often a barrier to their implementation. This paper proposes an effective way of designing, fabricating and erecting gridshells. The “Patchwork Gridshell” consists of a number of efficient elastic gridshell patches assembled using rigid gridshell frames. It can easily generate a number of different configurations, use a wide range of materials, and allows more architectural expression of practical long-span forms. The benefits of combining the ingenuously simple efficiency of elastic lattices and the power of digital fabrication are demonstrated by digitally rebuilding four alternative configurations of the Japan Pavilion of the Hanover Expo 2000 as a case study. The result is a flexible digital workflow which creates large column-free spaces that are capable of being constructed efficiently by nonspecialist contractors.</p

Patchwork Gridshells::Using Modularity to Facilitate Prefabrication and Simplify Construction

Modern architectural design has seen a shift towards iconic doubly-curved envelopes enclosing large column-free spaces. Gridshells have long been considered an efficient solution to such designs, but their actual use in practice has not spread worldwide. For elastic gridshells, their advantages in terms of substantial material savings can often be overshadowed by the significant challenges associated with their construction. Similarly, for rigid gridshells, the manufacture of a large number of different members and nodal connections is often a barrier to their implementation. This paper proposes an effective way of designing, fabricating and erecting gridshells. The “Patchwork Gridshell” consists of a number of efficient elastic gridshell patches assembled using rigid gridshell frames. It can easily generate a number of different configurations, use a wide range of materials, and allows more architectural expression of practical long-span forms. The benefits of combining the ingenuously simple efficiency of elastic lattices and the power of digital fabrication are demonstrated by digitally rebuilding four alternative configurations of the Japan Pavilion of the Hanover Expo 2000 as a case study. The result is a flexible digital workflow which creates large column-free spaces that are capable of being constructed efficiently by nonspecialist contractors.</p

Renal Proliferative and Phenotypic Changes in Rats With Two-Kidney, One-Clip Goldblatt Hypertension

Angiotensin II (All) is a vasoconstrictive peptide with hypertrophic and mitogenic effects on many cell types. Previous studies have shown that in vivo administration of All in rats results in proliferation of, and phenotypic changes in, many renal cell populations, but in doses also causing hypertension. Thus, it was not possible to differentiate nonhemodynamic from hypertensive effects of All. Therefore, we studied rats with renin-dependent, All-mediated hypertension (the two-kidney, oneclip Goldblatt model; mean systolic blood pressure 238 ± 48 ν 140 ± 6 mm Hg in sham-operated controls). The undipped kidneys, which were exposed to high blood pressure, developed significant glomerular and tubulointerstitial injury, tubulointerstitial cell proliferation, dense focal interstitial monocyte-macrophage influx, increased deposition of types I and IV collagen, as well as increased cellular expression of desmin and actin, in tubulointerstitial areas when examined at 11 weeks. In contrast, clipped kidneys, protected from hypertension but with high local renin expression, had minimal abnormalities. These studies suggest that in this model increased renin, and presumably All, does not mediate significant proliferative or phenotypic changes in the kidney in the absence of hypertension at 11 weeks. Am J Hypertens 1994;7:177-18

A 7-year dataset for driving and evaluating snow models at an arctic site (Sodankylä, Finland)

Datasets derived from measurements at Sodankylä, Finland, for driving and evaluating snow models are presented. This is the first time that such complete datasets have been made available for a site in the Arctic. The continuous October 2007&ndash;September 2014 driving data comprise all of the meteorological variables required as inputs for physically based snow models at hourly intervals: incoming solar and longwave radiation, snowfall and rainfall rates, air temperature, humidity, wind speed and atmospheric pressure. Two versions of the driving data are provided: one using radiation and wind speed measurements made above the height of the trees around the clearing where the evaluation data were measured and one with adjustments for the influence of the trees on conditions close to the ground. The available evaluation data include automatic and manual measurements of bulk snow depth and snow water equivalent, and profiles of snow temperature, snow density and soil temperature. A physically based snow model is driven and evaluated with the datasets to illustrate their utility. Shading by trees is found to extend the duration of both modelled and observed snow cover on the ground by several days a year

Engineering of tomato for the sustainable production of ketocarotenoids and its evaluation in aquaculture feed

Ketocarotenoids are high-value pigments used commercially across multiple industrial sectors as colorants and supplements. Chemical synthesis using petrochemical-derived precursors remains the production method of choice. Aquaculture is an example where ketocarotenoid supplementation of feed is necessary to achieve product viability. The biosynthesis of ketocarotenoids, such as canthaxanthin, phoenicoxanthin, or astaxanthin in plants is rare. In the present study, complex engineering of the carotenoid pathway has been performed to produce high-value ketocarotenoids in tomato fruit (3.0 mg/g dry weight). The strategy adopted involved pathway extension beyond β-carotene through the expression of the β-carotene hydroxylase (CrtZ) and oxyxgenase (CrtW) from Brevundimonas sp. in tomato fruit, followed by β-carotene enhancement through the introgression of a lycopene β-cyclase (β-Cyc) allele from a Solanum galapagense background. Detailed biochemical analysis, carried out using chromatographic, UV/VIS, and MS approaches, identified the predominant carotenoid as fatty acid (C14:0 and C16:0) esters of phoenicoxanthin, present in the S stereoisomer configuration. Under a field-like environment with low resource input, scalability was shown with the potential to deliver 23 kg of ketocarotenoid/hectare. To illustrate the potential of this “generally recognized as safe” material with minimal, low-energy bioprocessing, two independent aquaculture trials were performed. The plant-based feeds developed were more efficient than the synthetic feed to color trout flesh (up to twofold increase in the retention of the main ketocarotenoids in the fish fillets). This achievement has the potential to create a new paradigm in the renewable production of economically competitive feed additives for the aquaculture industry and beyond