Flavonoid glycosides from Periploca laevigata (Asclepiadaceae) from Algeria

The phytochemical investigation of the n-butanol extract of aerial parts of Periploca laevigata resulted in the isolation of four known compounds, kaempferol 3-O-β-arabinopyranoside (1), kaempferol 3-O-β-glucopyranoside (2), quercetin 3-O-arabinopyranoside (3) and quercetin 3-O-rutinoside (4).The structures of the compounds were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR as well as acid hydrolysis and comparison with the related known compounds

Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

Phytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. & Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control

Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

International audiencePhytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. &amp; Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control.</p

Chemical constituents and in vitro anti-inflammatory activity of Cistanche violacea Desf. (Orobanchaceae) extract

A new iridoid (1) and a new phenylethanoid glycoside (4), together with five known compounds (2, 3, 5, 6 and 7), were isolated for the first time from the ethyl acetate soluble part of the hydroalcoholic extract of the aerial parts of Cistanche violacea Desf. (Orobanchaceae), an endemic species of the North of the Sahara. The structures of these compounds have been elucidated on the basis of extensive 2D NMR spectroscopic analysis, including COSY, TOCSY, NOESY, HSQC, CIGAR-HMBC, H2BC and HSQC-TOCSY. All compounds were isolated from C. violacea for the first time. The anti-inflammatory activity of the EtOAc extract of C. violacea, was investigated by using human red blood cell (HRBC) membrane stabilization and inhibition of the albumin denaturation method. This study demonstrates, for the first time the effectiveness of C. violacea in combating inflammation, this might be believed to be influenced by the synergistic action of the above isolated compounds. The present study suggests that C. violacea would serve as a source for the discovery of novel anti-inflammatory agents.A new iridoid (1) and a new phenylethanoid glycoside (4), together with five known compounds (2, 3, 5, 6 and 7), were isolated for the first time from the ethyl acetate soluble part of the hydroalcoholic extract of the aerial parts of Cistanche violacea Desf. (Orobanchaceae), an endemic species of the North of the Sahara. The structures of these compounds have been elucidated on the basis of extensive 2D NMR spectroscopic analysis, including COSY, TOCSY, NOESY, HSQC, CIGAR-HMBC, H2BC and HSQC-TOCSY. All compounds were isolated from C. violacea for the first time. The anti-inflammatory activity of the EtOAc extract of C. violacea, was investigated by using human red blood cell (HRBC) membrane stabilization and inhibition of the albumin denaturation method. This study demonstrates, for the first time the effectiveness of C. violacea in combating inflammation, this might be believed to be influenced by the synergistic action of the above isolated compounds. The present study suggests that C. violacea would serve as a source for the discovery of novel anti-inflammatory agents

Antioxidant activity and chemical constituents of Warionia saharae Benth. & Coss. (Compositae) from Algeria.

International audiencePhytochemical investigations of chloroform and ethyl acetate extracts from the aerial parts of Warionia saharae Benth. &amp; Coss. from Algeria resulted in the isolation of ten known compounds: β-sitosterol, stigmasterol, scopoletin, cirsimaritin, chrysoeriol, hispidulin, luteolin, esculetin, (2R,3R) taxifolin, quercetin. Their structures were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. The EtOAc extract which was evaluated for DPPH radical scavenging activity and of lipid peroxide inhibition showed potent antioxidant ability compared to the quercetin and ascorbic acid used as positive control.</p

A new isoflavone from Genista saharae (Fabaceae)

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Secondary Metabolites from Linaria tingitana

The genus Linaria belongs to the Scrophulariaceae family and comprises about 200 species [1]. It is represented by 39 in Algeria [2]; several species have been used in folk medicine as tonics, antiscorbutics, laxatives, antidiabetics, and diuretics [3, 4]. Previous work on this genus has shown the presence of iridoids, diterpenoids, flavonoids, alkaloids, and phenylethanoids [4–9].Peer Reviewe

Chemical constituents of Linaria reflexa Desf.(Scrophulariaceae)

The phytochemical study on the aerial parts of Linaria reflexa Desf., belonging to the scrophulariaceae family led the isolation and structural elucidation of pectolinarin (1), linariin (2), methyl linoleate (3), apigenin (4), mannitol (5) and pectolinarigenin (6). These compounds were identified by 1D and 2D NMR as well as by mass spectrometry.We are grateful to MESRS (DGRSDT) Algeria for financial supports.Peer Reviewe