23,960 research outputs found
An experimental study of plane mixing layer development
Mean flow and turbulence was measured in the near field of two plane mixing layers in air with a maximum velocity of 21 m/sec. The experimental rig enabled mixing layers of velocity ratios 0 and 0.46 to be generated simultaneously. Gases with both tripped and untripped initial boundary layers were studied. It was found that the two stream layer developed to the self preserving state in a distance much shorter than did the single stream layer which followed accepted criteria for the development distance. The asymptotic levels of the turbulence quantities in the two stream layer and the development of the single stream layer showed agreement with existing data. It is suggested that the two stream mixing layer should provide a better test case for the development of turbulence models and calculation methods than the single stream mixing layer
A study of the factors affecting boundary layer two-dimensionality in wind tunnels
The effect of screens, honeycombs, and centrifugal blowers on the two-dimensionality of a boundary layer on the test section floors of low-speed blower tunnels is studied. Surveys of the spanwise variation in surface shear stress in three blower tunnels revealed that the main component responsible for altering the spanwise properties of the test section boundary layer was the last screen, thus confirming previous findings. It was further confirmed that a screen with varying open-area ratio, produced an unstable flow. However, contrary to popular belief, it was also found that for given incoming conditions and a screen free of imperfections, its open-area ratio alone was not enough to describe its performance. The effect of other geometric parameters such as the type of screen, honeycomb, and blower were investigated. In addition, the effect of the order of components in the settling chamber, and of wire Reynolds number were also studied
Double-branched vortex generator
In order to assess the suitability of using a double branched vortex generator in parametric studies involving vortex interactions, an experimental study of the main vortex and secondary flows produced by a double branched vortex generator was conducted in a 20-by-40 cm indraft wind tunnel. Measurements of the cross flow velocities were made with a five hole pressure probe from which vorticity contours and vortex parameters were derived. The results showed that the optimum configuration consisted of chord extensions with the absence of a centerbody
Sensitivity of the structure of untripped mixing layers to small changes in initial conditions
An experimental study was conducted concerning the influence of small changes in initial conditions on the near- and far-field evolution of the three-dimensional structure of a plan mixing layer. A two-stream mixing layer with a velocity ratio of 0.6 was generated with the initial boundary layers on the splitter plate laminar and was nominally two-dimensional. The initial conditions were changed slightly by interchanging the high- and low-speed sides of the wind tunnel, while maintaining the same velocities, and hence velocity ratio. This resulted in small changes in the initial boundary layer properties, and the perturbations present in the boundary layers were interchanged between the high- and low-speed sides for the two cases. The results indicate that, even with this relatively minor change in initial conditions, the near-field regions of the two cases differ significantly. The peak Reynolds stress levels in the near-field differ by up to 100 percent, and this is attributed to a difference in the location of the initial spanwise vortex roll-up. In addition, the positions and shapes of the individual streamwise vortical structures differ for the two cases, although the overall structures differ for the two cases, although the overall qualitative description of these structures is comparable. The subsequent reorganization and decay of the streamwise vortical structures is very similar for the two cases. As a result, in the far field, both mixing layers achieve similar structure, yielding comparable growth rates, Reynolds stress, distribution, and spectral content
A 3-component laser-Doppler velocimeter data acquisition and reduction system
A laser doppler velocimeter capable of measuring all three components of velocity simultaneously in low-speed flows is described. All the mean velocities, Reynolds stresses, and higher-order products can be evaluated. The approach followed is to split one of the two colors used in a 2-D system, thus creating a third set of beams which is then focused in the flow from an off-axis direction. The third velocity component is computed from the known geometry of the system. The laser optical hardware and the data acquisition electronics are described in detail. In addition, full operating procedures and listings of the software (written in BASIC and ASSEMBLY languages) are also included. Some typical measurements obtained with this system in a vortex/mixing layer interaction are presented and compared directly to those obtained with a cross-wire system
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Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections.
Background Most studies evaluating extragenital testing performance for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) detection by the Xpert® CT/NG show high per cent agreement with comparison assays; however, the precision around positive per cent agreement is low and thus the values that have been reported are not highly informative. Therefore, a systematic review was conducted and data from five studies were combined to better assess positive per cent agreement.MethodsThe literature indexed on PubMed.gov was searched. Included studies were those that were an evaluation of the Xpert CT/NG assay with rectal and/or pharyngeal specimen types compared with another nucleic acid amplification test (NAAT), the Aptima transcription mediated amplification assay. A full Bayesian method was used for bivariate fixed-effect meta-analysis of positive and negative per cent agreement and pooled estimates (and 95% confidence intervals (CI)) were presented for each.ResultsThe pooled positive and negative per cent agreement for detection of CT in rectal specimens was 89.72% (95% CI: 84.97%, 93.64%) and 99.23% (95% CI: 98.74%, 99.60%), and in pharyngeal specimens, they were 89.96% (95% CI: 66.38%, 99.72%) and 99.62% (95% CI: 98.95%, 99.95%) respectively. For NG detection in rectal specimens, the pooled positive and negative per cent agreement was 92.75% (95% CI: 87.91%, 96.46%) and 99.75% (95% CI: 99.46%, 99.93%), and in pharyngeal specimens, they were 92.51% (95% CI: 85.84%, 97.18%) and 98.56% (95% CI: 97.69%, 99.23%) respectively.ConclusionsIt was found that the Xpert CT/NG assay performed similarly to the Aptima transcription mediated amplification assay for the detection of CT and NG in extragenital specimens. The Xpert assay has the benefit of providing faster results at the point-of-care, thus reducing the turnaround time for results, potentially enabling same-day treatment
Virus isolation studies suggest short-term variations in abundance in natural cyanophage populations of the Indian Ocean
Cyanophage abundance has been shown to fluctuate over long timescales and with depth, but little is known about how it varies over short timescales. Previous short-term studies have relied on counting total virus numbers and therefore the phages which infect cyanobacteria cannot be distinguished from the total count.
In this study, an isolation-based approach was used to determine cyanophage abundance from water samples collected over a depth profile for a 24 h period from the Indian Ocean. Samples were used to infect Synechococcus sp. WH7803 and the number of plaque forming units (pfu) at each time point and depth were counted. At 10 m phage numbers were similar for most time-points, but there was a distinct peak in abundance at 0100 hours. Phage numbers were lower at 25 m and 50 m and did not show such strong temporal variation. No phages were found below this depth. Therefore, we conclude that only the abundance of phages in surface waters showed a clear temporal pattern over a short timescale. Fifty phages from a range of depths and time points were isolated and purified. The molecular diversity of these phages was estimated using a section of the phage-encoded psbD gene and the results from a phylogenetic analysis do not suggest that phages from the deeper waters form a distinct subgroup
Dynamics at the angle of repose: jamming, bistability, and collapse
When a sandpile relaxes under vibration, it is known that its measured angle
of repose is bistable in a range of values bounded by a material-dependent
maximal angle of stability; thus, at the same angle of repose, a sandpile can
be stationary or avalanching, depending on its history. In the nearly jammed
slow dynamical regime, sandpile collapse to a zero angle of repose can also
occur, as a rare event. We claim here that fluctuations of {\it dilatancy} (or
local density) are the key ingredient that can explain such varied phenomena.
In this work, we model the dynamics of the angle of repose and of the density
fluctuations, in the presence of external noise, by means of coupled stochastic
equations. Among other things, we are able to describe sandpile collapse in
terms of an activated process, where an effective temperature (related to the
density as well as to the external vibration intensity) competes against the
configurational barriers created by the density fluctuations.Comment: 15 pages, 1 figure. Minor changes and update
Menstrual health management: Knowledge and practices among adolescent girls
Objectives: To assess the knowledge and attitude of adolescent girls regarding menstruation and menstrual hygiene.Material and Methods: After approval by the ethical committee , the study was conducted on 340 adolescent girls aged 12-19 years, belonging to an urban slum area of Delhi. This was a questionnaire based cross-sectional study conducted over a period of 9 months in a tertiary hospital. Confidentiality of the subjects was ensured.Results: Out of 340 girls 69 % were between 16-19 years. Source of information about menstruation in majority of the cases was mother (60%). Only 48% girls knew menstruation before menarche and 24% girls knew uterus as the organ for menstruation. 71 % girls used sterile sanitary napkins as absorbent. Satisfactory changing of pads (>2pads/day) was done by 68 % and 77% girls cleaned the genitalia satisfactorily (>2 times/day). 41% girls were aware of the fact that unhygienic use of pad could be a source of genital infection and 8% girls had associated vaginal discharge. Social restrictions during menses in the form of religious activities, drop out from school, avoiding certain foods etc were practiced in many families.Conclusion: Although the menstrual practices appear to be satisfactory in major percentage of girls but knowledge regarding menstrual hygiene is worrisome, as maximum girls are unaware of menarche and physiology of menstruation. Inclusion of such information in the school curriculum and wider coverage in mass media will help to bridge this gap.Keywords: Adolescence; hygiene; menstruation healt
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