6,168 research outputs found

    Large deviations of a modified Jackson network: stability and rough asymptotics

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    Consider a modified, stable, two node Jackson network where server 2 helps server 1 when server 2 is idle. The probability of a large deviation of the number of customers at node one can be calculated using the flat boundary theory of Schwartz and Weiss [Large Deviations Performance Analysis (1994), Chapman and Hall, New York]. Surprisingly, however, these calculations show that the proportion of time spent on the boundary, where server 2 is idle, may be zero. This is in sharp contrast to the unmodified Jackson network which spends a nonzero proportion of time on this boundary.Comment: Published at http://dx.doi.org/10.1214/105051604000000666 in the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org

    The Development of A Performance Measurement Concept for the Royal Australian Air Force

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    he Royal Australian Air Force (RAAF) needed to develop performance measurements (PMs) to support its Program Management and Budgeting (PMB) System. This research assessed the use of the concepts of the Theory of Constraints (TOC) to develop those PMs. The literature indicated that: traditional accounting PMs were not always suitable in an environment of continuous improvement; Activity Based Costing did not provide the required measures; and non-financial PMs were supplanting the older measures. Further, governments faced unique problems in developing PMs, particularly in defining the outcomes to be measured. Using the Critical Theory and Action Research methodologies, and a case study approach, the research derived guidelines from PMB to develop the RAAF PMs, examined the possible use of TOC in government organizations, developed an example of PMs which could be used by the RAAF, and compared the developed PMs with the PMB guidelines. The research found that difficulties arose when operationally defining the outputs of the RAAF, requiring the use of proxy measures. However, with slight modifications, the TOC concepts could be applied to the development of RAAF PMs. Development would be an iterative process, requiring refinements as users gained experience with the PMs

    Bodies and Structures: Deep-Mapping Modern East Asian History

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    Presentation at the conference "Bridging the Methodological Gap: Devising Collaborative Quantitative and Qualitative Research Projects on Japan," University of Michigan Center for Japanese Studies, November 2019

    Characterisation of bacterioplankton communities in the meltwater ponds of Bratina Island, Victoria Land, Antarctica

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    A unique collection of Antarctic aquatic environments (meltwater ponds) lies in close proximity on the rock and sediment-covered undulating surface of the McMurdo Ice Shelf, near Bratina Island (Victoria Land, Antarctica). During the 2009–10 mid-austral summer, sets of discrete water samples were collected across the vertical geochemical gradients of five meltwater ponds (Egg, P70E, Legin, Salt and Orange) for geochemical and microbial community structure analysis. Bacterial DNA fingerprints (using Automated Ribosomal Intergenic Spacer Analysis) statistically clustered communities within ponds based on ANOSIM (R = 0.766, P = 0.001); however, one highly stratified pond (Egg) had two distinct depth-related bacterial communities (R = 0.975, P = 0.008). 454 pyrosequencing at three depths within Egg also identified phylum level shifts and increased diversity with depth, Bacteroidetes being the dominant phyla in the surface sample and Proteobacteria being dominant in the bottom two depths. BEST analysis, which attempts to link community structure and the geochemistry of a pond, identified conductivity and pH individually, and to a lesser extent Ag109, NO2 and V51 as dominant influences to the microbial community structure in these ponds. Increasing abundances of major halo-tolerant OTUs across the strong conductivity gradient reinforce it as the primary driver of community structure in this stud

    Mining whole sample mass spectrometry proteomics data for biomarkers: an overview

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    In this paper we aim to provide a concise overview of designing and conducting an MS proteomics experiment in such a way as to allow statistical analysis that may lead to the discovery of novel biomarkers. We provide a summary of the various stages that make up such an experiment, highlighting the need for experimental goals to be decided upon in advance. We discuss issues in experimental design at the sample collection stage, and good practise for standardising protocols within the proteomics laboratory. We then describe approaches to the data mining stage of the experiment, including the processing steps that transform a raw mass spectrum into a useable form. We propose a permutation-based procedure for determining the significance of reported error rates. Finally, because of its general advantages in speed and cost, we suggest that MS proteomics may be a good candidate for an early primary screening approach to disease diagnosis, identifying areas of risk and making referrals for more specific tests without necessarily making a diagnosis in its own right. Our discussion is illustrated with examples drawn from experiments on bovine blood serum conducted in the Centre for Proteomic Research (CPR) at Southampton University

    Simplicial Ricci Flow

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    We construct a discrete form of Hamilton's Ricci flow (RF) equations for a d-dimensional piecewise flat simplicial geometry, S. These new algebraic equations are derived using the discrete formulation of Einstein's theory of general relativity known as Regge calculus. A Regge-Ricci flow (RRF) equation is naturally associated to each edge, L, of a simplicial lattice. In defining this equation, we find it convenient to utilize both the simplicial lattice, S, and its circumcentric dual lattice, S*. In particular, the RRF equation associated to L is naturally defined on a d-dimensional hybrid block connecting \ell with its (d-1)-dimensional circumcentric dual cell, L*. We show that this equation is expressed as the proportionality between (1) the simplicial Ricci tensor, Rc_L, associated with the edge L in S, and (2) a certain volume weighted average of the fractional rate of change of the edges, lambda in L*, of the circumcentric dual lattice, S*, that are in the dual of L. The inherent orthogonality between elements of S and their duals in S* provide a simple geometric representation of Hamilton's RF equations. In this paper we utilize the well established theories of Regge calculus, or equivalently discrete exterior calculus, to construct these equations. We solve these equations for a few illustrative examples.Comment: 34 pages, 10 figures, minor revisions, DOI included: Commun. Math. Phy

    The role of cryptic dispersal in shaping connectivity patterns of marine populations in a changing world

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    Genetic connectivity directly shapes the demographic profile of marine species, and has become one of the most intensely researched areas in marine ecology. More importantly, it has changed the way we design and describe Marine Protected Areas across the world. Population genetics is the preferred tool when measuring connectivity patterns, however, these methods often assume that dispersal patterns are 1) natural and 2) follow traditional meta-population models. In this short review, we formally introduce the phenomenon of cryptic dispersal, where multiple introductory events can undermine these assumptions, resulting in grossly inaccurate connectivity estimates. We also discuss the evolutionary consequences of cryptic dispersal and advocate for a cross-disciplinary approach that incorporates larval transport models into population genetic studies to provide a level of oceanographic realism that will result in more accurate estimates of dispersal. As globalized trade continues to expand, the rate of anthropogenic movement of marine organisms is also expected to increase and as such, integrated methods will be required to meet the inevitable conservation challenges that will arise from it

    Benthic microbial communities of coastal terrestrial and ice shelf Antarctic meltwater ponds.

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    The numerous perennial meltwater ponds distributed throughout Antarctica represent diverse and productive ecosystems central to the ecological functioning of the surrounding ultra oligotrophic environment. The dominant taxa in the pond benthic communities have been well described however, little is known regarding their regional dispersal and local drivers to community structure. The benthic microbial communities of 12 meltwater ponds in the McMurdo Sound of Antarctica were investigated to examine variation between pond microbial communities and their biogeography. Geochemically comparable but geomorphologically distinct ponds were selected from Bratina Island (ice shelf) and Miers Valley (terrestrial) (<40 km between study sites), and community structure within ponds was compared using DNA fingerprinting and pyrosequencing of 16S rRNA gene amplicons. More than 85% of total sequence reads were shared between pooled benthic communities at different locations (OTU0.05), which in combination with favorable prevailing winds suggests aeolian regional distribution. Consistent with previous findings Proteobacteria and Bacteroidetes were the dominant phyla representing over 50% of total sequences; however, a large number of other phyla (21) were also detected in this ecosystem. Although dominant Bacteria were ubiquitous between ponds, site and local selection resulted in heterogeneous community structures and with more than 45% of diversity being pond specific. Potassium was identified as the most significant contributing factor to the cosmopolitan community structure and aluminum to the location unique community based on a BEST analysis (Spearman's correlation coefficient of 0.632 and 0.806, respectively). These results indicate that the microbial communities in meltwater ponds are easily dispersed regionally and that the local geochemical environment drives the ponds community structure

    [Review of] David W. Baird, The Quapaw Indians: a History of the Downstream People

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    Baird, in a highly engaging book, examines the history of a little known Indian tribe. Originally inhabitants of the Ohio Valley, the Quapaws, by 1973, had migrated to the area around the Arkansas and Mississippi Rivers where they were first encountered by the French. Considered important allies by the French and later the Spanish, the Quapaws served as a buffer against the British and British-allied Indians. The results of contacts with Europeans, however, were soon felt by the Quapaws; by 1763 their population had dropped to seven hundred from an estimated six to fifteen thousand in 1682
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