Impact of carboxymethylcellulose and water Addition on baking quality and physicochemical Properties of gluten-free bread

El objetivo de este estudio fue determinar la influencia de la adición de agua y de carboximetilcelulosa (CMC) en las propiedades fisicoquímicas y de calidad de pan libre de glu-ten (GF), elaborado con harina de arroz, almidón de maíz y almidón de yuca. La harina de arroz presentó los valores más altos de índice de absorción de agua (WAI) e índice de solu-bilidad de agua (WSI). Las concentraciones de CMC y agua fueron de 1-3% y 80-90%, con base en la harina de arroz, componente mayoritario de la mezcla, respectivamente. Se utilizó la Metodología de Superficie de Respuesta (MSR). Los valores máximos para el volumen específico (3,92mL/g) y la altura (77,82mm), se mostraron con 85% de agua y 2% de CMC. El mayor rendimiento, se evidenció con 3% de CMC y 80% de agua, pero este tratamiento tuvo el volumen especí-fico y la altura más baja. En cuanto a las propiedades textur-ales, la combinación de 3% de CMC y 80% de agua generó una miga con la mayor firmeza (16,6N) y dureza (91,2N); los valores más bajos de estos parámetros, se presentaron con 85% de agua y 2% de CMC. El mayor valor de cohesividad (0,46), se registró con 90% de agua y 3% de CMC y la con-dición más baja de cohesividad, se reportó con 80% de agua y 1% de CMC. La inclusión de mayores concentraciones de CMC (3%) genera productos GF, con mayor firmeza, cohe-sividad, elasticidad y dureza.The objective of this study was to determine the influence of water and carboxymethylcellulose (CMC) addition on physi-cochemical properties and baking quality of gluten-free (GF) bread made from rice flour, corn and cassava starch. Rice flour showed the highest values of water absorption index (WAI) and water solubility index (WSI). The CMC concentra-tions and moisture content were 1-3% and 80-90%, based on rice flour, major component of the mixture, respectively. Response Surface Methodology (RSM) was used. The maxi-mum values for the specific volume (3.92mL/g) and height (77.82mm) are presented with 85% moisture content and 2% CMC. The best yields were obtained with 3% CMC and 80% moisture content; but this treatment had the lowest specific volume and height. As for the textural properties, the com-bination of 3% CMC and 80% moisture content resulted in higher firmness crumb (16.6N) and hardness (91.2N), the lowest values of these parameters were presented with 85% moisture content and 2% CMC. The higher cohesiveness value (0.46) was showed with 90% moisture content and 3% CMC, and lower cohesiveness condition reported with 80% moisture content and 1% CMC. The adding of higher con-centrations of CMC (3%) resulted in GF products with more firmness, cohesiveness, elasticity and hardness.Incluye referencias bibliográfica

Influence of the Cumulative Incidence of COVID-19 Cases on the Mental Health of the Spanish Out-of-Hospital Professionals

This study aimed to analyze the psychological affectation of health professionals (HPs) of Spanish Emergency Medical Services (EMSs) according to the cumulative incidence (CI) of COVID19 cases in the regions in which they worked. A cross-sectional descriptive study was designed, including all HPs working in any EMS of the Spanish geography between 1 February 2021 and 30 April 2021. Their level of stress, anxiety and depression (DASS-21) and the perception of self-efficacy (GSES) were the study’s main results. A 2-factor analysis of covariance was used to determine if the CI regions of COVID-19 cases determined the psychological impact on each of the studied variables. A total of 1710 HPs were included. A third presented psychological impairment classified as severe. The interaction of CI regions with the studied variables did not influence their levels of stress, anxiety, depression or self-efficacy. Women, younger HPs or those with less EMS work experience, emergency medical technicians (EMT), workers who had to modify their working conditions or those who lived with minors or dependents suffered a greater impact from the COVID-19 pandemic in certain regions. These HPs have shown high levels of stress, anxiety, depression and medium levels of self-efficacy, with similar data in the different geographical areas. Psychological support is essential to mitigate their suffering and teach them to react to adverse events.This research was funded by Fundación ASISA and Sociedad Española de Urgencias y Emergencias (SEMES)

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

IMPACTO DE LA ADICIÓN DE CABOXIMETILCELULOSA Y AGUA EN LAS PROPIEDADES FISICOQUÍMICAS Y DE CALIDAD DE PAN LIBRE DE GLUTEN

El objetivo de este estudio fue determinar la influencia de la adición de agua y de carboximetilcelulosa (CMC) en las propiedades fisicoquímicas y de calidad de pan libre de gluten (GF), elaborado con harina de arroz, almidón de maíz y almidón de yuca. La harina de arroz presentó los valores más altos de índice de absorción de agua (WAI) e índice de solubilidad de agua (WSI). Las concentraciones de CMC y agua fueron de 1-3% y 80-90%, con base en la harina de arroz, componente mayoritario de la mezcla, respectivamente. Se utilizó la Metodología de Superficie de Respuesta (MSR). Los valores máximos para el volumen específico (3,92mL/g) y la altura (77,82mm), se mostraron con 85% de agua y 2% de CMC. El mayor rendimiento, se evidenció con 3% de CMC y 80% de agua, pero este tratamiento tuvo el volumen específico y la altura más baja. En cuanto a las propiedades texturales, la combinación de 3% de CMC y 80% de agua generó una miga con la mayor firmeza (16,6N) y dureza (91,2N); los valores más bajos de estos parámetros, se presentaron con 85% de agua y 2% de CMC. El mayor valor de cohesividad (0,46), se registró con 90% de agua y 3% de CMC y la condición más baja de cohesividad, se reportó con 80% de agua y 1% de CMC. La inclusión de mayores concentraciones de CMC (3%) genera productos GF, con mayor firmeza, cohesividad, elasticidad y dureza