1,191 research outputs found

    A systematic review of the use of organization and management theories in climate change studies

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    Climate change studies have been gaining increasing importance in the academic debate, and also in the field of organizations and management. Scholars have contributed to this field by borrowing approaches from sustainable business research. However, some authors have raised unanswered questions about the contribution of these studies to the management theories. According to them, climate change studies have failed to provide theoretical insights and too often they have adopted a descriptive and practical approach. Our review describes the theoretical contribution of the climate change papers, identifying the most often used management theories. The analysis results for 28 different management theories indicate that, while some theories such as the institutional and stakeholder theories have been widely debated, the relation between business climate change strategies and other organization theories still appears to be unexplored

    The Emotional Impact of Patient Loss on Brazilian Veterinarians

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    Simple Summary Unlike human physicians, veterinarians may follow their patients throughout their lifetime, from conception to end-of-life care. Due to the high involvement with the animal, healthcare providers (veterinarians and veterinary staff) are likely to be exposed, together with the caregivers, to the impact of negative events including death and euthanasia. The degree course of veterinary medicine should contain a course that prepares future veterinarians for bad news delivery in order to better handle these challenging situations. Along with the need to further explore this topic, veterinarians should be taught how to recognize psychological fatigue and avoid burnout, seek medical and psychotherapeutic advice, look for ways to lessen these effects and make it easier to identify workers who are most susceptible to burnout early on.Abstract Veterinarians, unlike human physicians, could potentially care for the patient for several years, from conception to end-of-life care. Because of their close relationship with the animal, healthcare providers (for example, veterinarians and staff) are more likely to be affected by bad events and end-of-life care. The purpose of this study was to assess the emotional impact of patients' deaths on Brazilian veterinarians; 549 Brazilian veterinarians (78.3% females) completed a 20-item online questionnaire. Females were more emotionally affected than males by having to talk to the owner about their animal's death and more emotionally affected by the animal's death itself. Furthermore, the emotional impact of an animal's death was heavily influenced by the number of animals euthanized and varied greatly across veterinarians based on their age, with vets over 50 years old being less affected than vets between the ages of 31 and 40. The majority of responders (91.0%) were not trained to deal with grief during their degree. Those who had some training reported being less affected by bereavement. These findings indicate that patient death is a significant emotional concern for veterinarians. Specific education during the degree course, aimed at preparing future veterinarians to deal with death and death communication, is lacking but necessary

    Transferring the Integrated Pollution Prevention and Control (IPPC) Approach and Best Available Techniques (BAT) Concepts to Egypt, Tunisia and Morocco

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    The principles introduced by the Directive Concerning Integrated Pollution Prevention and Control (IPPC) (currently known as the Industrial Emissions Directive (2010/75/EU)) are innovative and have raised interests in the framework of the literature debate on environmental regulation. Many articles describe and analyze the application of the Directive in European countries, but only a few articles focus on how the interest for the Directive's principles, including the integrated approach, have reached countries outside the European Union. This paper aims to contribute to this topic, describing the experience of the authors in carrying out an EU-funded project on transferring the IPPC approach and Best Available Techniques (BAT) concepts to three Arab countries, i.e. , Egypt, Morocco and Tunisia. The paper presents the experience referring to two sectors falling within the scope of the IPPC Directive: the textile and dairy sector. The objectives, methodologies, activities and experiences are described and can be used and valorized to integrate the IPPC approach and BAT concepts in the current environmental legislation of the three countries

    Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation

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    N-acetylaspartate (NAA) is synthesized by the mitochondrial enzyme NAT8L, which uses acetyl-CoA and aspartate as substrates. These metabolites are fundamental for bioenergetics and anabolic requirements of highly proliferating cells, thus, NAT8L modulation may impinge on the metabolic reprogramming of cancer cells. Specifically, aspartate represents a limiting amino acid for nucleotide synthesis in cancer. Here, the expression of the NAT8L enzyme was modulated to verify how it impacts the metabolic adaptations and proliferative capacity of hepatocellular carcinoma. We demonstrated that NAT8L downregulation is asso-ciated with increased proliferation of hepatocellular carcinoma cells and immortalized hepatocytes. The over -expression of NAT8L instead decreased cell growth. The pro-tumoral effect of NAT8L silencing depended on glutamine oxidation and the rewiring of glucose metabolism. Mechanistically, NAT8L downregulation triggers aspartate outflow from mitochondria via the exporter SLC25A13 to promote glucose flux into the pentose phosphate pathway, boosting purine biosynthesis. These results were corroborated by the analyses of human and mouse hepatocellular carcinoma samples revealing a decrease in NAT8L expression compared to adjacent non -tumoral tissues. Overall, this work demonstrates that NAT8L expression in liver cells limits the cytosolic avail-ability of aspartate necessary for enhancing the pentose phosphate pathway and purine biosynthesis, counter-acting cell proliferation

    Eco-innovative practices for sustainable consumption and production: what are the possible benefits for companies ?

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    The paper aims to present some eco-innovative practices regarding Sustainable Consumption and Production (SCP). The study also focuses on potential benefits for the actors who implement these practices, mainly with reference to companies. After a literature review on the actual importance of SCP and on the effects of eco-innovation tools and policies on companies, authors present the developed eco-innovation practices in three focus areas related to sustainable consumption and production. The aim of the study is to contribute to literature studies on SCP with the development of eco-innovative practices resulting by the integration of existing tools, by pointing out and valorizing their potentials and synergies. These practices have been pointing out in the framework of the international European project. Three focus areas are involved by the practices: sustainability of products and services, sustainability of production processes and sustainable management of industrial areas. Authors developed four eco innovative practices resulting from the integration of 15 existing tools. These practices offer many opportunities to many actors, mainly companies and public authorities, in order to achieve environmental and competitive benefits and implement eco-innovation principles with a cooperative and shared approach
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