1,464 research outputs found
Trade and the Environment
Trade, the exchange of goods and services across countries, is often viewed as an engine of economic growth. Benefits of liberalized trade include access to a larger variety of goods and services to consumers, easier access to foreign technologies, access to larger markets for producers, and increased efficiency in resource allocation. The impact of trade on the environment, however, is a contentious issue; air and water pollution, the degradation of natural habitats and loss of species, and global pollutants, particularly carbon dioxide emissions, are major concerns.Environmental Economics and Policy, International Relations/Trade,
When Government Spending Serves the Elites: Consequences for Economic Growth in a Context of Market Imperfections
Government spending should be regarded as a social and political phenomenon, not merely as a technical choice. We argue that there is an implicit contract between the organized elites and politicians which often leads to a pro-elite allocation of public resources. A natural and simple taxonomy of government spending follows from this view: spending in public goods broadly defined which mitigate market failures versus spending in non-social subsidies, mainly a vehicle to serve the elites. We theoretically and empirically show that pro-elite spending biases are costly in terms of economic growth. The empirical findings are exceptionally robust.government spending, economic growth, market imperfections, investment, subsidies, International Development, Labor and Human Capital, Political Economy, Public Economics,
Pollution and the State: The Role of the Structure of Government
Government spending has significant environmental implications. This paper analyzes the effect of the allocation of government spending between public goods broadly defined and private goods or non-social subsidies on air and water pollution. The theoretical model predicts that a reallocation of expenditures from private subsidies to public goods improves environmental quality by reducing production pollution. We estimate an empirical model that shows that such a reallocation causes a significant reduction in air pollutants namely sulfur dioxide and lead and an improvement in water quality measures including dissolved oxygen and biological oxygen demand.
Answer Set Programming for Non-Stationary Markov Decision Processes
Non-stationary domains, where unforeseen changes happen, present a challenge
for agents to find an optimal policy for a sequential decision making problem.
This work investigates a solution to this problem that combines Markov Decision
Processes (MDP) and Reinforcement Learning (RL) with Answer Set Programming
(ASP) in a method we call ASP(RL). In this method, Answer Set Programming is
used to find the possible trajectories of an MDP, from where Reinforcement
Learning is applied to learn the optimal policy of the problem. Results show
that ASP(RL) is capable of efficiently finding the optimal solution of an MDP
representing non-stationary domains
Oxygen abundances in unevolved metal-poor stars from near-UV OH lines
We have performed a detailed oxygen abundance analysis of 23 metal-poor
(-3.0<[Fe/H]<-0.3) unevolved halo stars and one giant through the OH bands in
the near UV, using high-resolution echelle spectra. Oxygen is found to be
overabundant with respect to iron in these stars, with the [O/Fe] ratio
increasing from 0.6 to 1 between [Fe/H]=-1.5 and -3.0. The behavior of the
oxygen overabundance with respect to [Fe/H] is similar to that seen in previous
works based on OI IR triplet data (Abia and Rebolo 1989; Tomkin et al. 1992;
Cavallo, Pilachowski, and Rebolo 1997). Contrary to the previously accepted
picture, our oxygen abundances, derived from low-excitation OH lines, agree
well with those derived from high-excitation lines of the triplet. For nine
stars in common with Tomkin et al. we obtain a mean difference of 0.00+/-0.11
dex with respect to the abundances determined from the triplet using the same
stellar parameters and model photospheres. For four stars in our sample we have
found measurements of the [OI] 6300 A line in the literature, from which we
derive oxygen abundances consistent (average difference 0.09 dex) with those
based on OH lines, showing that the long standing controversy between oxygen
abundances from forbidden and permitted lines in metal-poor unevolved stars can
be resolved. Our new oxygen abundances show a smooth extension of the
Edvardsson et al.'s (1993) [O/Fe] versus metallicity curve to much lower
abundances, with a slope -0.31+/- 0.11 (taking into account the error bars in
both oxygen abundances and metallicities) in the range -3<[Fe/H]<-1.Comment: 17 pages, 8 figures, 3 table
High-throughput biointerfaces for direct, label-free, and multiplexed metaplasmonic biosensing
In recent years, metaplasmonic biosensors have emerged as a novel counterpart of well-established plasmonic biosensors based on thin metallic layers. Metaplasmonic biosensors offer high potential for sensor miniaturiza-tion, extreme sensitivity biosensing, and high multiplexing capabilities with detection methods free of coupling optical elements. These capabilities make metaplasmonic biosensors highly attractive for Point-of-Care and handled/portable devices or novel On-Chip devices; as a result, it has increased the number of prototypes and potential applications that emerged during the last years. One of the main challenges to achieving fully operative devices is the achievement of high-throughput biointerfaces for sensitive and selective biodetection in complex media. Despite the superior surface sensitivity achieved by metaplasmonic sensors compared to conventional plasmonic sensors based on metallic thin films, the main limitations to achieving high-throughput and multiplexed biosensing usually are associated with the sensitivity and selectivity of the bioin-terface and, as a consequence, their application to the direct analysis of real complex samples. This graphical review discusses the potential challenges and capabilities of different biofunctionalization strategies, biorecog-nition elements, and antifouling strategies to achieve scalable and high-throughput metaplasmonic biosensing for Point-of-Care devices and bioengineering applications like Organs-On-Chip
Spectroscopic Observations of Convective Patterns in the Atmospheres of Metal-Poor Stars
Convective line asymmetries in the optical spectrum of two metal-poor stars,
Gmb1830 and HD140283, are compared to those observed for solar metallicity
stars. The line bisectors of the most metal-poor star, the subgiant HD140283,
show a significantly larger velocity span that the expectations for a
solar-metallicity star of the same spectral type and luminosity class. The
enhanced line asymmetries are interpreted as the signature of the lower metal
content, and therefore opacity, in the convective photospheric patterns. These
findings point out the importance of three-dimensional convective velocity
fields in the interpretation of the observed line asymmetries in metal-poor
stars, and in particular, urge for caution when deriving isotopic ratios from
observed line shapes and shifts using one-dimensional model atmospheres.
The mean line bisector of the photospheric atomic lines is compared with
those measured for the strong Mg I b1 and b2 features. The upper part of the
bisectors are similar, and assuming they overlap, the bottom end of the
stronger lines, which are formed higher in the atmosphere, goes much further to
the red. This is in agreement with the expected decreasing of the convective
blue-shifts in upper atmospheric layers, and compatible with the high velocity
redshifts observed in the chromosphere, transition region, and corona of
late-type stars.Comment: 27 pages, LaTeX; 10 Figures (14 PostScript files); to be published in
The Astrophysical Journa
Dosing regimen of meropenem for adults with severe burns : a population pharmacokinetic study with Monte Carlo simulations
Objectives To develop a population model to describe the pharmacokinetics (PK) of intravenous meropenem in adult patients with severe burns and investigate potential relationships between dosage regimens and antimicrobial efficacy.Patients and methods A dose of 1 g every 8 h was administered to adult patients with total body surface area burns of â„15%. Doses for subsequent courses were determined using results from the initial course and the patient's clinical condition. Five plasma meropenem concentrations were typically measured over the dosage interval on one to four occasions. An open, two-compartment PK model was fitted to the meropenem concentrations using NONMEM and the effect of covariates on meropenem PK was investigated. Monte Carlo simulations investigated dosage regimens to achieve a target T>MIC for â„40%, â„60% or â„80% of the dose interval.Results Data comprised 113 meropenem concentration measurements from 20 dosage intervals in 12 patients. The parameters were CL (L/h)â=â0.196 L/h/kgâĂâ[1âââ0.023âĂâ(ageâââ46)]âĂâ[1âââ0.049âĂâ(albuminâââ15)], V1â=â0.273 L/kgâĂâ[1âââ0.049âĂâ(albuminâââ15)], Qâ=â0.199 L/h/kg and V2â=â0.309 L/kgâĂâ[1âââ0.049âĂâ(albuminâââ15)]. For a target of â„80% T>MIC, the breakpoint was 8 mg/L for doses of 1 g every 4 h and 2 g every 8 h given over 3 h, but only 4 mg/L if given over 5 min.Conclusions Although 1 g 8 hourly should be effective against Escherichia coli and CoNS, higher doses, ideally with a longer infusion time, would be more appropriate for empirical therapy, mixed infections and bacteria with MIC values â„4 mg/L
Studying the non-thermal lobes of IRAS 16547-4247 through a multi-wavelength approach
In recent years, massive protostars have turned out to be a possible population of high-energy emitters. Among the best candidates is IRAS 16547-4247, a protostar that presents a powerful outflow with clear signatures of interaction with its environment. This source has been revealed to be a potential high-energy source because it displays non-thermal radio emission of synchrotron origin, which is evidence of relativistic particles. To improve our understanding of IRAS 16547-4247 as a high-energy source, we analyzed XMM-Newton archival data and found that IRAS 16547-4247 is a hard X-ray source. We discuss these results in the context of a refined one-zone model and previous radio observations. From our study we find that it may be difficult to explain the X-ray emission as non-thermal radiation coming from the interaction region, but it might be produced by thermal Bremsstrahlung (plus photo-electric absorption) by a fast shock at the jet end. In the high-energy range, the source might be detectable by the present generation of Cherenkov telescopes, and may eventually be detected by Fermi in the GeV range
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