3,247 research outputs found
Signatures of the Youngest Starbursts: Optically-thick Thermal Bremsstrahlung Radio Sources in Henize 2-10
VLA radio continuum imaging reveals compact (<8 pc) ~1 mJy radio sources in
the central 5" starburst region of the blue compact galaxy Henize 2-10. We
interpret these radio knots as extremely young, ultra-dense HII regions. We
model their luminosities and spectral energy distributions, finding that they
are consistent with unusually dense HII regions having electron densities, 1500
cm^-3 < n_e < 5000 cm^-3, and sizes of 3-8 pc. Since these H II regions are not
visible in optical images, we propose that the radio data preferentially reveal
the youngest, densest, and most highly obscured starforming events. Energy
considerations imply that each of the five \HII regions contains ~750 O7V
equivalent stars, greater than the number found in 30 Doradus in the LMC. The
high densities imply an over-pressure compared to the typical interstellar
medium so that such objects must be short-lived (<0.5 Myr expansion
timescales). We conclude that the radio continuum maps reveal the very young
(<0.5 Myr) precursors of ``super starclusters'' or ``proto globular clusters''
which are prominent at optical and UV wavelengths in He 2-10. If the
ultra-dense HII regions are typical of those which we predict will be found in
other starbursting systems, then super starclusters spend 15% of their lifetime
in heavily-obscured environments, similar to Galactic ultra-compact HII
regions. This body of work leads us to propose that massive extragalactic star
clusters (i.e. proto globular clusters) with ages <10^6 yr may be most easily
identified by finding compact radio sources with optically-thick thermal
bremsstrahlung spectral signatures.Comment: AASTeX, 8 figures 2 included with psfig in text; other 6 in jpeg
format; Postscript versions of figures may be found at
http://zem.ucolick.org/chip/Research/young_clusters.html -- Accepted for
publication in the Astrophysical Journa
Balmer and Metal Absorption Feature Gradients in M32
Spectra from MDM Observatory are used to assess Lick/IDS feature strength
gradients inside the half-light radius of the compact Local Group elliptical
galaxy M32. All but a few (of 24 measured) indices show a statistically
significant gradient. Comparing with models, the index gradients indicate a
mean age and abundance gradient in the sense that the nucleus is a factor of
2.5 younger and a factor of 0.3 dex more metal-rich than at 1 effective radius.
This conclusion is only weakly dependent on which index combinations are used
and is robust to high accuracy. Stars near the M32 nucleus have a mean age and
heavy element abundance [M/H] of (4.7 Gyr, +0.02), judging from models by
Worthey with variable abundance ratios. This result has very small formal
random errors, although, of course, there is significant age-metallicity
degeneracy along an (age, abundance) line segment from (5.0 Gyr, 0.00) to (4.5
Gyr, +0.05). An abundance pattern of [C/M]=+0.077, [N/M]=-0.13, [Mg/M]=-0.18,
[Fe/M]~0.0, and [Na/M]=+0.12 is required to fit the feature data, with a
fitting precision of about 0.01 dex. Model uncertainties make the accuracies of
these values at least twice the magnitude of the precision. Forcing
scaled-solar abundances does not change the age very much, but it increases the
rms goodness of model-data fit by a factor of 3 and broadens the allowed range
of age to Gyr. The overall abundance pattern contrasts with larger
elliptical galaxies, in which all measurable lighter elements are enhanced
relative to iron and calcium.Comment: 23 pages, 9 figures, Astronomical Journal, in pres
Untangling Source-To-Sink Geochemical Signals in a ~3.5 Ga Martian Lake: Sedimentology and Geochemistry of the Murray Formation
Sedimentary rocks are historical archives of planetary surface processes; their grains, textures, and chemistry integrate the effects of source terrains, paleoclimatic conditions, weathering and transport processes, authigenic mineral precipitation, and diagenesis, which records groundwater chemistry through time. Source to Sink basin analysis seeks to constrain the influence of each of these different signals through sedimentary and geochemical analyses. Here, we use Mars Science Laboratory (MSL) Curiosity rover images and geochemical and mineralogical data from a traverse across a portion of the Murray formationthe lowermost unit exposed in the Gale crater central moundto begin to constrain the aspects of the source to sink system that formed this Martian mudstone between 3.7 and 3.2 Ga
A multi-layer extension of the stochastic heat equation
Motivated by recent developments on solvable directed polymer models, we
define a 'multi-layer' extension of the stochastic heat equation involving
non-intersecting Brownian motions.Comment: v4: substantially extended and revised versio
Treatment with Soluble Activin Receptor Type IIB Alters Metabolic Response in Chemotherapy-Induced Cachexia
Some chemotherapeutic agents have been shown to lead to the severe wasting syndrome known as cachexia resulting in dramatic losses of both skeletal muscle and adipose tissue. Previous studies have shown that chemotherapy-induced cachexia is characterized by unique metabolic alterations. Recent results from our laboratory and others have shown that the use of ACVR2B/Fc, a soluble form of the activin receptor 2B (ACVR2B), can mitigate muscle wasting induced by chemotherapy, although the underlying mechanisms responsible for such protective effects are unclear. In order to understand the biochemical mechanisms through which ACVR2B/Fc functions, we employed a comprehensive, multi-platform metabolomics approach. Using both nuclear magnetic resonance (NMR) and mass-spectrometry (MS), we profiled the metabolome of both serum and muscle tissue from four groups of mice including (1) vehicle, (2) the chemotherapeutic agent, Folfiri, (3) ACVR2B/Fc alone, and (4) combined treatment with both Folfiri and ACVR2B/Fc. The metabolic profiles demonstrated large effects with Folfiri treatment and much weaker effects with ACVR2B/Fc treatment. Interestingly, a number of significant effects were observed in the co-treatment group, with the addition of ACVR2B/Fc providing some level of rescue to the perturbations induced by Folfiri alone. The most prominent of these were a normalization of systemic glucose and lipid metabolism. Identification of these pathways provides important insights into the mechanism by which ACVR2B/Fc protects against chemotherapy-induced cachexia
Rethinking clinical trials of transcranial direct current stimulation: Participant and assessor blinding is inadequate at intensities of 2mA
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source are credited. The article was made available through the Brunel University Open Access Publishing Fund.Background: Many double-blind clinical trials of transcranial direct current stimulation (tDCS) use stimulus intensities of 2 mA despite the fact that blinding has not been formally validated under these conditions. The aim of this study was to test the assumption that sham 2 mA tDCS achieves effective blinding. Methods:
A randomised double blind crossover trial. 100 tDCS-naĂŻve healthy volunteers were incorrectly advised that they there were taking part in a trial of tDCS on word memory. Participants attended for two separate sessions. In each session, they completed a word memory task, then received active or sham tDCS (order randomised) at 2 mA stimulation intensity for 20 minutes and then repeated the word memory task. They then judged whether they believed they had received active stimulation and rated their confidence in that judgement. The blinded assessor noted when red marks were observed at the electrode sites post-stimulation. Results: tDCS at 2 mA was not effectively blinded. That is, participants correctly judged the stimulation condition greater than would be expected to by chance at both the first session (kappa level of agreement (Îş) 0.28, 95% confidence interval (CI) 0.09 to 0.47 p = 0.005) and the second session (Îş = 0.77, 95%CI 0.64 to 0.90), p = <0.001) indicating inadequate participant blinding. Redness at the reference electrode site was noticeable following active stimulation more than sham stimulation (session one, Îş = 0.512, 95%CI 0.363 to 0.66, p<0.001; session two, Îş = 0.677, 95%CI 0.534 to 0.82) indicating inadequate assessor blinding. Conclusions: Our results suggest that blinding in studies using tDCS at intensities of 2 mA is inadequate. Positive results from such studies should be interpreted with caution.GLM is supported by the National Health & Medical Research Council of Australia ID 571090
Vector meson dominance and the rho meson
We discuss the properties of vector mesons, in particular the rho^0, in the
context of the Hidden Local Symmetry (HLS) model. This provides a unified
framework to study several aspects of the low energy QCD sector. Firstly, we
show that in the HLS model the physical photon is massless, without requiring
off field diagonalization. We then demonstrate the equivalence of HLS and the
two existing representations of vector meson dominance, VMD1 and VMD2, at both
tree level and one loop order. Finally the S matrix pole position is shown to
provide a model and process independent means of specifying the rho mass and
width, in contrast to the real axis prescription currently used in the Particle
Data Group tables.Comment: 18 pages, REVTE
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