339 research outputs found
Selective Methods of Teaching Secondary English: The Scarlet Letter: A Study and Application of the Collaborative and Mastery Learning Methods
This study is about the relationship of content in teaching to the process in teaching for the purpose of helping students to become better readers of literature. This study investigates two selected teaching strategies supported by research to be effective, and applies them to the teaching of a canonical piece of literature, The Scarlet Letter by Nathaniel Hawthorne. This study employs literary theory in the development of the objectives and applies both cooperative learning and mastery learning methods to the teaching of this novel. Two sets of lesson plans are developed from the objectives and subsequently analyzed for their effectiveness against a set of criteria established by experts. The study then hypothetically compares and contrasts each method and examines their appropriateness in relationship to achieving the stated objectives
Re-entrant ferroelectricity in liquid crystals
The ferroelectric (Sm C) -- antiferroelectric (Sm C) -- reentrant
ferroelectric (re Sm C) phase temperature sequence was observed for system
with competing synclinic - anticlinic interactions. The basic properties of
this system are as follows (1) the Sm C phase is metastable in temperature
range of the Sm C stability (2) the double inversions of the helix
handedness at Sm C -- Sm C and Sm C% -- re-Sm C phase
transitions were found (3) the threshold electric field that is necessary to
induce synclinic ordering in the Sm C phase decreases near both Sm
C -- Sm C and Sm C -- re-Sm C phase boundaries, and it has
maximum in the middle of the Sm C stability region. All these properties
are properly described by simple Landau model that accounts for nearest
neighboring layer steric interactions and quadrupolar ordering only.Comment: 10 pages, 5 figures, submitted to PR
Full 3D modelling of pulse propagation enables efficient nonlinear frequency conversion with low energy laser pulses in a single-element tripler
Although new optical materials continue to open up access to more and more wavelength bands where femtosecond laser pulses can be generated, light frequency conversion techniques are still indispensable in filling the gaps on the ultrafast spectral scale. With high repetition rate, low pulse energy laser sources (oscillators) tight focusing is necessary for a robust wave mixing and the efficiency of broadband nonlinear conversion is limited by diffraction as well as spatial and temporal walk-off. Here we demonstrate a miniature third harmonic generator (tripler) with conversion efficiency exceeding 30%, producing 246 fs UV pulses via cascaded second order processes within a single laser beam focus. Designing this highly efficient and ultra compact frequency converter was made possible by full 3-dimentional modelling of propagation of tightly focused, broadband light fields in nonlinear and birefringent media
Molten Salt Thermal Energy Storage Systems
The feasibility of storing thermal energy at temperatures of 450 C to 535 C in the form of latent heat of fusion was examined for over 30 inorganic salts and salt mixtures. Alkali carbonate mixtures were chosen as phase-change storage materials in this temperature range because of their relatively high storage capacity and thermal conductivity, moderate cost, low volumetric expansion upon melting, low corrosivity, and good chemical stability. Means of improving heat conduction through the solid salt were explored
Disparities in European healthcare system approaches to maintaining continuity of medication for non-communicable diseases during the COVID-19 outbreak
SAWA experiment ? properties of mineral dust aerosol as seen by synergic lidar and sun-photometer measurements
International audienceWe propose a method of retrieving basic information on mineral dust aerosol particles from synergic sun-photometer and multi-wavelength lidar measurements as well as from the observations of lidar light depolarisation. We use this method in a case study of mineral dust episode in Central Europe. Lidar signals are inversed with a modified Klett-Fernald algorithm. Aerosol optical depth measured with the sun-photometer allows to reduce uncertainties in the inversion procedure through which we estimate vertical profile of aerosol extinction. Next we assume that aerosol particles may be represented by ensemble of randomly oriented, identical spheroids. Having calculated vertical profiles of aerosol extinction coefficients for lidar wavelengths, we compute the profiles of local Angstrom exponent. We use laser beam depolarisation together with the calculated Angstrom exponents to estimate the shapes (aspect ratios) and sizes of the spheroids. Numerical calculations are performed with the transition matrix (T-matrix) algorithm by M. Mishchenko. The proposed method was first used during SAWA measurement campaign in Warsaw, spring 2005, to characterise the particles of desert dust, drifting over Poland with a southern-eastern wind (13?14 April). Observations and T-matrix calculations show that mode radii of spheroids representative for desert aerosols' particles are in the range of 0.15?0.3 ?m, while their aspect ratios are lower than 0.7 or larger than 1.7
A Cross-Sectional Survey on Medication Management Practices for Noncommunicable Diseases in Europe During the Second Wave of the COVID-19 Pandemic
Maintaining healthcare for noncommunicable diseases (NCDs) is particularly important during the COVID-19 pandemic; however, diversion of resources to acute care, and physical distancing restrictions markedly affected management of NCDs. We aimed to assess the medication management practices in place for NCDs during the second wave of the COVID-19 pandemic across European countries. In December 2020, the European Network to Advance Best practices & technoLogy on medication adherencE (ENABLE) conducted a cross-sectional, web-based survey in 38 European and one non-European countries. Besides descriptive statistics of responses, nonparametric tests and generalized linear models were used to evaluate the impact on available NCD services of the number of COVID-19 cases and deaths per 100,000 inhabitants, and gross domestic product (GDP) per capita. Fifty-three collaborators from 39 countries completed the survey. In 35 (90%) countries face-to-face primary-care, and out-patient consultations were reduced during the COVID-19 pandemic. The mean ± SD number of available forms of teleconsultation services in the public healthcare system was 3 ± 1.3. Electronic prescriptions were available in 36 (92%) countries. Online ordering and home delivery of prescription medication (avoiding pharmacy visits) were available in 18 (46%) and 26 (67%) countries, respectively. In 20 (51%) countries our respondents were unaware of any national guidelines regarding maintaining medication availability for NCDs, nor advice for patients on how to ensure access to medication and adherence during the pandemic. Our results point to an urgent need for a paradigm shift in NCD-related healthcare services to assure the maintenance of chronic pharmacological treatments during COVID-19 outbreaks, as well as possible future disasters
Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the needs of the patients. In particular, geriatric and paediatric populations as well as dermatological patients have special needs/preferences that should be considered when designing drug products. Patient Centric Drug Product Pharmaceutical Design (PCDPD) offers the opportunity to meet the needs and preferences of patients. Packaging, orodispersible formulations, fixed dose combinations products, multiparticulate formulations, topical formulations and 3D printing are of particular relevance in a PCDPD process. These will be addressed in this review as well as their impact on medication adherence
Persistence as a robust indicator of medication adherence-related quality and performance
Medication adherence is a priority for health systems worldwide and is widely recognised as a key component of quality of care for disease management. Adherence-related indicators were rarely explicitly included in national health policy agendas. One barrier is the lack of standardised adherence terminology and of routine measures of adherence in clinical practice. This paper discusses the possibility of developing adherence-related performance indicators highlighting the value of measuring persistence as a robust indicator of quality of care. To standardise adherence and persistence-related terminology allowing for benchmarking of adherence strategies, the European Ascertaining Barriers for Compliance (ABC) project proposed a Taxonomy of Adherence in 2012 consisting of three components: initiation, implementation, discontinuation. Persistence, which immediately precedes discontinuation, is a key element of taxonomy, which could capture adherence chronology allowing the examination of patterns of medication-taking behaviour. Advances in eHealth and Information Communication Technology (ICT) could play a major role in providing necessary structures to develop persistence indicators. We propose measuring persistence as an informative and pragmatic measure of medication-taking behaviour. Our view is to develop quality and performance indicators of persistence, which requires investing in ICT solutions enabling healthcare providers to review complete information on patients’ medication-taking patterns, as well as clinical and health outcomes
The Need to Develop Standard Measures of Patient Adherence for Big Data: Viewpoint
Despite half a century of dedicated studies, medication adherence remains far from perfect, with many patients not taking their medications as prescribed. The magnitude of this problem is rising, jeopardizing the effectiveness of evidence-based therapies. An important reason for this is the unprecedented demographic change at the beginning of the 21st century. Aging leads to multimorbidity and complex therapeutic regimens that create a fertile ground for nonadherence. As this scenario is a global problem, it needs a worldwide answer. Could this answer be provided, given the new opportunities created by the digitization of health care? Daily, health-related information is being collected in electronic health records, pharmacy dispensing databases, health insurance systems, and national health system records. These big data repositories offer a unique chance to study adherence both retrospectively and prospectively at the population level, as well as its related factors. In order to make full use of this opportunity, there is a need to develop standardized measures of adherence, which can be applied globally to big data and will inform scientific research, clinical practice, and public health. These standardized measures may also enable a better understanding of the relationship between adherence and clinical outcomes, and allow for fair benchmarking of the effectiveness and cost-effectiveness of adherence-targeting interventions. Unfortunately, despite this obvious need, such standards are still lacking. Therefore, the aim of this paper is to call for a consensus on global standards for measuring adherence with big data. More specifically, sound standards of formatting and analyzing big data are needed in order to assess, uniformly present, and compare patterns of medication adherence across studies. Wide use of these standards may improve adherence and make health care systems more effective and sustainable
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