32 research outputs found
Observations of the Askaryan Effect in Ice
We report on the first observations of the Askaryan effect in ice: coherent impulsive radio Cherenkov radiation from the charge asymmetry in an electromagnetic (EM) shower. Such radiation has been observed in silica sand and rock salt, but this is the first direct observation from an EM shower in ice. These measurements are important since the majority of experiments to date that rely on the effect for ultra-high energy neutrino detection are being performed using ice as the target medium. As part of the complete validation process for the Antarctic Impulsive Transient Antenna (ANITA) experiment, we performed an experiment at the Stanford Linear Accelerator Center (SLAC) in June 2006 using a 7.5 metric ton ice target, yielding results fully consistent with theoretical expectations
Characterizing COVID-19 clinical phenotypes and associated comorbidities and complication profiles
Purpose Heterogeneity has been observed in outcomes of hospitalized patients with coronavirus disease 2019 (COVID-19). Identification of clinical phenotypes may facilitate tailored therapy and improve outcomes. The purpose of this study is to identify specific clinical phenotypes across COVID-19 patients and compare admission characteristics and outcomes. Methods This is a retrospective analysis of COVID-19 patients from March 7, 2020 to August 25, 2020 at 14 U.S. hospitals. Ensemble clustering was performed on 33 variables collected within 72 hours of admission. Principal component analysis was performed to visualize variable contributions to clustering. Multinomial regression models were fit to compare patient comorbidities across phenotypes. Multivariable models were fit to estimate associations between phenotype and in-hospital complications and clinical outcomes. Results The database included 1,022 hospitalized patients with COVID-19. Three clinical phenotypes were identified (I, II, III), with 236 [23.1%] patients in phenotype I, 613 [60%] patients in phenotype II, and 173 [16.9%] patients in phenotype III. Patients with respiratory comorbidities were most commonly phenotype III (p = 0.002), while patients with hematologic, renal, and cardiac (all p<0.001) comorbidities were most commonly phenotype I. Adjusted odds of respiratory, renal, hepatic, metabolic (all p<0.001), and hematological (p = 0.02) complications were highest for phenotype I. Phenotypes I and II were associated with 7.30- fold (HR:7.30, 95% CI:(3.11-17.17), p<0.001) and 2.57-fold (HR:2.57, 95% CI:(1.10-6.00), p = 0.03) increases in hazard of death relative to phenotype III. Conclusion We identified three clinical COVID-19 phenotypes, reflecting patient populations with different comorbidities, complications, and clinical outcomes. Future research is needed to determine the utility of these phenotypes in clinical practice and trial design
New Limits on the Ultra-high Energy Cosmic Neutrino Flux from the ANITA Experiment
We report initial results of the first flight of the Antarctic Impulsive
Transient Antenna (ANITA-1) 2006-2007 Long Duration Balloon flight, which
searched for evidence of a diffuse flux of cosmic neutrinos above energies of 3
EeV. ANITA-1 flew for 35 days looking for radio impulses due to the Askaryan
effect in neutrino-induced electromagnetic showers within the Antarctic ice
sheets. We report here on our initial analysis, which was performed as a blind
search of the data. No neutrino candidates are seen, with no detected physics
background. We set model-independent limits based on this result. Upper limits
derived from our analysis rule out the highest cosmogenic neutrino models. In a
background horizontal-polarization channel, we also detect six events
consistent with radio impulses from ultra-high energy extensive air showers.Comment: 4 pages, 2 table
Observation of Ultra-high-energy Cosmic Rays with the ANITA Balloon-borne Radio Interferometer
We report the observation of sixteen cosmic ray events of mean energy of 1.5
x 10^{19} eV, via radio pulses originating from the interaction of the cosmic
ray air shower with the Antarctic geomagnetic field, a process known as
geosynchrotron emission. We present the first ultra-wideband, far-field
measurements of the radio spectral density of geosynchrotron emission in the
range from 300-1000 MHz. The emission is 100% linearly polarized in the plane
perpendicular to the projected geomagnetic field. Fourteen of our observed
events are seen to have a phase-inversion due to reflection of the radio beam
off the ice surface, and two additional events are seen directly from above the
horizon.Comment: 5 pages, 5 figures, new figure adde
Observations of the Askaryan Effect in Ice
We report on the first observations of the Askaryan effect in ice: coherent
impulsive radio Cherenkov radiation from the charge asymmetry in an
electromagnetic (EM) shower. Such radiation has been observed in silica sand
and rock salt, but this is the first direct observation from an EM shower in
ice. These measurements are important since the majority of experiments to date
that rely on the effect for ultra-high energy neutrino detection are being
performed using ice as the target medium. As part of the complete validation
process for the Antarctic Impulsive Transient Antenna (ANITA) experiment, we
performed an experiment at the Stanford Linear Accelerator Center (SLAC) in
June 2006 using a 7.5 metric ton ice target, yielding results fully consistent
with theoretical expectations.Comment: 4 pages, 5 figures, minor correction
Energy and Flux Measurements of Ultra-High Energy Cosmic Rays Observed During the First ANITA Flight
The first flight of the Antarctic Impulsive Transient Antenna (ANITA)
experiment recorded 16 radio signals that were emitted by cosmic-ray induced
air showers. For 14 of these events, this radiation was reflected from the ice.
The dominant contribution to the radiation from the deflection of positrons and
electrons in the geomagnetic field, which is beamed in the direction of motion
of the air shower. This radiation is reflected from the ice and subsequently
detected by the ANITA experiment at a flight altitude of 36km. In this paper,
we estimate the energy of the 14 individual events and find that the mean
energy of the cosmic-ray sample is 2.9 EeV. By simulating the ANITA flight, we
calculate its exposure for ultra-high energy cosmic rays. We estimate for the
first time the cosmic-ray flux derived only from radio observations. In
addition, we find that the Monte Carlo simulation of the ANITA data set is in
agreement with the total number of observed events and with the properties of
those events.Comment: Added more explanation of the experimental setup and textual
improvement
Observation of Ultrahigh-Energy Cosmic Rays with the ANITA Balloon-Borne Radio Interferometer
We report the observation of 16 cosmic ray events with a mean energy of 1: 5 x 10(19) eV via radio pulses originating from the interaction of the cosmic ray air shower with the Antarctic geomagnetic field, a process known as geosynchrotron emission. We present measurements in the 300-900 MHz range, which are the first self-triggered, first ultrawide band, first far-field, and the highest energy sample of cosmic ray events collected with the radio technique. Their properties are inconsistent with current ground-based geosynchrotron models. The emission is 100% polarized in the plane perpendicular to the projected geomagnetic field. Fourteen events are seen to have a phase inversion due to reflection of the radio beam off the ice surface, and two additional events are seen directly from above the horizon. Based on a likelihood analysis, we estimate angular pointing precision of order 2 degrees for the event arrival directions