Research of the involvement of the members of the project teams in accessing the financing of the projects of the higher education institutions from Romania

This paper refers to the research of the acces needs of funds for university projects and involvement of project team members. The research aimed at: Evaluating and analyzing from a quantitative point of view the links that characterize the relationship between the needs of accessing project finance and the involvement of project team members, who are also employees of the university. The study consisted in applying an investigation method based on the questionnaire instrument that was designed in the original way regarding aspects such as: Identification of human resources – general characteristics of the project team members as respondents; Types of projects accessed in higher education institutions; Motivation and ways of accessing projects by universities; Expected results. The results of the researchers are concretized in establishing the premises of the role of human resources of the university projects in accessing the funds for their financing. The essence of the analyzes performed consists in conceptualizing the problem of obtaining the financial resources necessary to carry out the projects and awareness of training and development of the human resource involved

Magnetic Nanoemulsions for the Intra-Articular Delivery of Ascorbic Acid and Dexamethasone

(1) Osteoarthritis (OA) is a progressive joint degenerative disease that currently has no cure. Limitations in the development of innovative disease modifying therapies are related to the complexity of the underlying pathogenic mechanisms. In addition, there is the unmet need for efficient drug delivery methods. Magnetic nanoparticles (MNPs) have been proposed as an efficient modality for the delivery of bioactive molecules within OA joints, limiting the side effects associated with systemic delivery. We previously demonstrated MNP’s role in increasing cell proliferation and chondrogenesis. In the design of intra-articular therapies for OA, the combined NE-MNP delivery system could provide increased stability and biological effect. (2) Proprietary Fe3O4 MNPs formulated as oil-in-water (O/W) magneto nanoemulsions (MNEs) containing ascorbic acid and dexamethasone were tested for size, stability, magnetic properties, and in vitro biocompatibility with human primary adipose mesenchymal cells (ADSC), cell mobility, and chondrogenesis. In vivo biocompatibility was tested after systemic administration in mice. (3) We report high MNE colloidal stability, magnetic properties, and excellent in vitro and in vivo biocompatibility. By increasing ADSC migration potential and chondrogenesis, MNE carrying dexamethasone and ascorbic acid could reduce OA symptoms while protecting the cartilage layer

THE INFLUENCE OF CORPORATE SOCIAL RESPONSIBILITY ON HUMAN RESOURCES - CAREER FORMATION

<p><strong>Purpose</strong> - "the social responsibility" of the organization must include measures such as: stimulating the lifelong learning process, meaning "lifelong learning", giving decision-making responsibility to employees (delegation and participatory management), transparency and good information throughout the organization, a sustainable and general balance between work objectives or tasks and personal and / or family needs etc. </p><p><strong>Methodology/approach</strong> – online questionnaire used to collect the data, which allowed the analysis and explanation of the causal relationships between the variables. </p><p><strong>Findings</strong> - corporate social responsibility must include measures of transparency and good information throughout the company, a sustainable and general balance between objectives or work tasks but also measures for employees by providing equal treatment, a sustainable and equitable structure.</p><p><strong>Research limitations/implications</strong> - Romanian employees' interest in corporate social responsibility reports, their perception of the reasons for companies' involvement in such activities</p><p><strong>Practical implications</strong> - real support in making managerial decisions, thus bringing a series of contributions to the CSR activity of companies</p><p><strong>Originality/value</strong> - no Romanian research has been conducted to bring in the way employees perceive the CSR activities carried out and communicated by companies</p&gt

COVID-19 APPROACHES ON CORPORATE SOCIAL RESPONSIBILITY

<p><strong>Purpose</strong> - The purpose of this research is to identify how Romanian organizations have implemented corporate social responsibility models by examining employees' perceptions of the relationship between management behavior and actions and employee morale. </p><p><strong>Methodology/approach</strong> – Qualitative research based on case studies with used semi-structured interviews. The study contains data from 10 respondents from 7 companies and compiles enough information to understand the investigated phenomenon. </p><p><strong>Findings</strong> - The labor market impediments created by the Covid-19 pandemic, requires the update of the company's policies for permanent or remote employees, flexible employees and / or mixed location, but also for new employees. </p><p><strong>Research limitations/implications </strong>- the impossibility of extrapolating the results to the entire researched population. One of the limits of qualitative research is that only SMEs from Bucharest, Brașov, Cluj, Galați, Prahova are considered. Thus, the results are relatively particular and difficult to generalize. </p><p><strong>Practical implications</strong> - Most respondents agree that human resource management is one of the internal dimensions of corporate social responsibility.</p><p><strong>Originality/value</strong> - The contribution of this study is remarkable, as it explores the impact of the pandemic on the staff recruitment and selection process, but also on employee retention. </p&gt

Enhanced Multimodal Effect of Chemotherapy, Hyperthermia and Magneto-Mechanic Actuation of Silver-Coated Magnetite on Cancer Cells

Currently, various methods based on magnetic nanoparticles are being considered for the treatment of cancer. Among these, magnetic hyperthermia and magneto-mechanical actuation are the most tested physical methods that have shown promising results when applied both separately and in combination. However, combining them with specific drugs can further improve antitumor efficiency. In this study, we performed a systematic analysis to determine the best combination of hyperthermia, magneto-mechanical actuation of silver-coated magnetite nanoparticles (MNP@Ag) and chemotherapy (mitoxantrone) capable of destroying tumor cells in vitro while maintaining normal cells in their state of increased viability. The results showed that of the nine treatment configurations, the only one that satisfied the safety condition for normal cells (fibroblasts) and the highly cytotoxic condition for tumor cells (HeLa) was the combination of all three triggers. This combination led to the decrease in HeLa viability to about 32%, while the decrease in fibroblast viability reached 80%. It was observed that the cytotoxic effect was not a sum of the separate effects of each trigger involved, but the result of a nonlinear conjugation of the triggers in a dynamic regime imposed by the magneto-mechanical actuation of the nanoparticles. We conclude that by using such a treatment approach, the need for chemotherapeutic drugs can be substantially reduced while maintaining their therapeutic performance