The Effects of Hydrolytic Enzyme Treatments on Three British Columbian Interior Fir Kraft Pulps Differing in Their Initial Fiber Coarseness

The effects of carbohydrate-degrading enzymes on three softwood kraft pulps, differing primarily in their initial fiber coarseness, were assessed. The pulps were treated with three different enzyme preparations (a crude cellulase, an endoglucanase, and a xylanase) to assess the potential of the different enzymes to alter handsheet properties and to evaluate their effects on fiber coarseness. All enzymatic treatments increased handsheet densities irrespective of the furnish used. The most significant modifications in handsheet properties were evident after treatment with either the crude cellulase or the endoglucanase. Although increased densification occurred with all the pulps, the degree of fiber coarseness of the original pulp influenced the magnitude of response to the different enzymatic treatments. While the tensile index of the coarser pulp was improved by treatment with the crude cellulase, a similar trend was not evident with the pulps of lower coarseness. In contrast, the tensile strength of all pulps, irrespective of the inherent fiber coarseness, was improved by the endoglucanase treatments. The tear strength decreased after treatments with both the crude cellulase and endoglucanase. Xylanase treatments did not significantly alter the handsheet properties of any of the pulps, regardless of the nature of the starting furnish

Modelling of laboratory data of bi-directional reflectance of regolith surface containing Alumina

Bidirectional reflectance of a surface is defined as the ratio of the scattered radiation at the detector to the incident irradiance as a function of geometry. The accurate knowledge of the bidirectional reflection function (BRF) of layers composed of discrete, randomly positioned scattering particles is very essential for many remote sensing, engineering, biophysical applications and in different areas of Astrophysics. The computations of BRF's for plane parallel particulate layers are usually reduced to solve the radiative transfer equation (RTE) by the existing techniques. In this work we present our laboratory data on bidirectional reflectance versus phase angle for two sample sizes of 0.3 and 1 $\mu m$ of Alumina for the He-Ne laser at 632.8 nm (red) and 543.5nm(green) wavelength. The nature of the phase curves of the asteroids depends on the parameters like- particle size, composition, porosity, roughness etc. In our present work we analyse the data which are being generated using single scattering phase function i.e. Mie theory considering particles to be compact sphere. The well known Hapke formula will be considered along with different particle phase function such as Mie and Henyey Greenstein etc to model the laboratory data obtained at the asteroid laboratory of Assam University.Comment: 5 pages, 5 figures [accepted for publication in Publications of the Astronomical Society of Australia (PASA) on 8 June, 2011

Mental disorders and long-term labour market outcomes : nationwide cohort study of 2 055 720 individuals

Objective To examine the associations between an onset of serious mental disorders before the age of 25 with subsequent employment, income and education outcomes. Methods Nationwide cohort study including individuals (n = 2 055 720) living in Finland between 1988–2015, who were alive at the end of the year they turned 25. Mental disorder diagnosis between ages 15 and 25 was used as the exposure. The level of education, employment status, annual wage or self‐employment earnings, and annual total income between ages 25 and 52 (measurement years 1988–2015) were used as the outcomes. Results All serious mental disorders were associated with increased risk of not being employed and not having any secondary or higher education between ages 25 and 52. The earnings for individuals with serious mental disorders were considerably low, and the annual median total income remained rather stable between ages 25 and 52 for most of the mental disorder groups. Conclusions Serious mental disorders are associated with low employment rates and poor educational outcomes, leading to a substantial loss of total earnings over the life course.Peer reviewe

Prevention is better than cure, but...: Preventive medication as a risk to ordinariness?

Preventive health remains at the forefront of public health concerns; recent initiatives, such as the NHS health check, may lead to recommendations for medication in response to the identification of 'at risk' individuals. Little is known about lay views of preventive medication. This paper uses the case of aspirin as a prophylactic against heart disease to explore views among people invited to screening for a trial investigating the efficacy of such an approach. Qualitative interviews (N=46) and focus groups (N=5, participants 31) revealed dilemmas about preventive medication in the form of clashes between norms: first, in general terms, assumptions about the benefit of prevention were complicated by dislike of medication; second, the individual duty to engage in prevention was complicated by the need not to be over involved with one's own health; third, the potential appeal of this alternative approach to health promotion was complicated by unease about the implications of encouraging irresponsible behaviour among others. Though respondents made different decisions about using the drug, they reported very similar ways of trying to resolve these conflicts, drawing upon concepts of necessity and legitimisation and the special ordinariness of the particular dru

Solar Wind Properties and Geospace Impact of Coronal Mass Ejection-Driven Sheath Regions : Variation and Driver Dependence

We present a statistical study of interplanetary conditions and geospace response to 89 coronal mass ejection-driven sheaths observed during Solar Cycles 23 and 24. We investigate in particular the dependencies on the driver properties and variations across the sheath. We find that the ejecta speed principally controls the sheath geoeffectiveness and shows the highest correlations with sheath parameters, in particular in the region closest to the shock. Sheaths of fast ejecta have on average high solar wind speeds, magnetic (B) field magnitudes, and fluctuations, and they generate efficiently strong out-of-ecliptic fields. Slow-ejecta sheaths are considerably slower and have weaker fields and field fluctuations, and therefore they cause primarily moderate geospace activity. Sheaths of weak and strong B field ejecta have distinct properties, but differences in their geoeffectiveness are less drastic. Sheaths of fast and strong ejecta push the subsolar magnetopause significantly earthward, often even beyond geostationary orbit. Slow-ejecta sheaths also compress the magnetopause significantly due to their large densities that are likely a result of their relatively long propagation times and source near the streamer belt. We find the regions near the shock and ejecta leading edge to be the most geoeffective parts of the sheath. These regions are also associated with the largest B field magnitudes, out-of-ecliptic fields, and field fluctuations as well as largest speeds and densities. The variations, however, depend on driver properties. Forecasting sheath properties is challenging due to their variable nature, but the dependence on ejecta properties determined in this work could help to estimate sheath geoeffectiveness through remote-sensing coronal mass ejection observations.Peer reviewe

Vitamin D levels in women with polycystic ovary syndrome: a population-based study

Background: Conflicting evidence supports a role for vitamin D in women with reproductive disorders such as polycystic ovary syndrome (PCOS) but studies on large, unselected populations have been lacking. Methods: We conducted a general population-based study from the prospective Northern Finland Birth Cohort 1966 (NFBC1966). Serum 25-hydroksyvitamin D (25(OH)D) levels were evaluated in women with self-reported PCOS (n = 280) versus non-symptomatic controls (n = 1573) at the age of 31 with wide range of endocrine and metabolic confounders. Results: The levels of 25(OH)D were similar among women with and without self-reported PCOS (50.35 vs. 48.30 nmol/L, p = 0.051). Women with self-reported PCOS presented with a higher body mass index (BMI), increased insulin resistance, and low-grade inflammation and testosterone levels compared to controls. The adjusted linear regression model showed a positive association between total 25(OH)D levels in self-reported PCOS (β = 2.46, 95% confidence interval (CI) 0.84 to 4.08, p = 0.003). The result remained after adjustment for BMI, testosterone, homeostatic model assessment of insulin resistance (HOMA-IR), and high-sensitivity C-reactive protein (hs-CRP) levels. Conclusion: In this population-based setting, PCOS was associated with higher vitamin D levels when adjusting for confounding factors, without distinct beneficial effects on metabolic derangements

Directional characteristics of thermal-infrared beaming from atmosphereless planetary surfaces - a new thermophysical model

We present a new rough-surface thermophysical model (Advanced Thermophysical Model or ATPM) that describes the observed directional thermal emission from any atmosphereless planetary surface. It explicitly incorporates partial shadowing, scattering of sunlight, self-heating and thermal–infrared beaming (re-radiation of absorbed sunlight back towards the Sun as a result of surface roughness). The model is verified by accurately reproducing ground-based directional thermal emission measurements of the lunar surface using surface properties that are consistent with the findings of the Apollo missions and roughness characterized by an rms slope of ∼32°. By considering the wide range of potential asteroid surface properties, the model implies a beaming effect that cannot be described by a simple parameter or function. It is highly dependent on the illumination and viewing angles as well as surface thermal properties and is predominantly caused by macroscopic rather than microscopic roughness. Roughness alters the effective Bond albedo and thermal inertia of the surface as well as moving the mean emission away from the surface normal. For accurate determination of surface properties from thermal–infrared observations of unresolved bodies or resolved surface elements, roughness must be explicitly modelled, preferably aided with thermal measurements at different emission angles and wavelengths

Understanding the meaning of medications for patients: The medication experience

Objective: To understand and describe the meaning of medications for patients. Methods: A metasynthesis of three different, yet complementary qualitative research studies, was conducted by two researchers. The first study was a phenomenological study of patients’ medication experiences that used unstructured interviews. The second study was an ethnographic study of pharmaceutical care practice, which included participant observation, in-depth interviews and focus groups with patients of pharmaceutical care. The third was a phenomenological study of the chronic illness experience of medically uninsured individuals in the United States and included an explicit aim to understand the medication experience within that context. The two researchers who conducted these three qualitative studies that examined the medication experience performed the meta-synthesis. The process began with the researchers reviewing the themes of the medication experience for each study. The researchers then aggregated the themes to identify the overlapping and similar themes of the medication experience and which themes are sub-themes within another theme versus a unique theme of the medication experience. The researchers then used the analytic technique, “free imaginative variation” to determine the essential, structural themes of the medication experience. Results: The meaning of medications for patients was captured as four themes of the medication experience: a meaningful encounter; bodily effects; unremitting nature; and exerting control. The medication experience is an individual’s subjective experience of taking a medication in his daily life. It begins as an encounter with a medication. It is an encounter that is given meaning before it occurs. The experience may include positive or negative bodily effects. The unremitting nature of a chronic medication often causes an individual to question the need for the medication. Subsequently, the individual may exert control by altering the way he takes the medication and often in part because of the gained expertise with the medication in his own body. Conclusion: The medication experience is a practice concept that serves to understand patients’ experiences and to understand an individual patient’s medication experience and medication-taking behaviors in order to meet his or her medication-related needs

Effects of soil warming and nitrogen foliar applications on bud burst of black spruce

Key message: In mature black spruce, bud burst process is anticipated by soil warming, while delayed by foliar applications of nitrogen; however, the effects depend on growth conditions at the site. Abstract: The observation of phenological events can be used as biological indicator of environmental changes, especially from the perspective of climate change. In boreal forests, the onset of the bud burst is a key factor in the length of the growing season. With current climate change, the major factors limiting the growth of boreal trees (i.e., temperature and nitrogen availability) are changing and studies on mature trees are limited. The aim of this study was to investigate the effects of soil warming and increased nitrogen (N) deposition on bud burst of mature black spruce [Picea mariana (Mill.) BSP]. From 2008 onwards, an experimental manipulation of these environmental growth conditions was conducted in two stands (BER and SIM) at different altitudes in the boreal forest of Quebec, Canada. An increase in soil temperature (H treatment) and a canopy application of artificial rain enriched with nitrogen (N treatment) were performed. Observations of bud phenology were made during May–July 2012 and 2013. In BER, H treatment caused an anticipation (estimated as 1–3 days); while N treatment, a delay (estimated as 1–2 days but only in 2012) in bud burst. No treatments effect was significant in SIM. It has been demonstrated that soil temperature and N availability can play an important role in affecting bud burst in black spruce but the effects of these environmental factors on growth are closely linked with site conditions