Hybrid striped bass: Fingerling production in ponds

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Assessing Novel Lidar Modalities for Maximizing Coverage of a Spaceborne System through the Use of Diode Lasers

Current satellite lidars have sparse spatial coverage, leading to uncertainty from sampling. This complicates robust change detection and does not allow applications that require continuous coverage. One potential way to increase lidar sampling density is to use more efficient lasers. All current spaceborne lidars use solid-state lasers with a limited efficiency of 5–8%. In this paper, we investigate the potential for using diode lasers, with their higher efficiencies, as an alternative. Diode lasers have reported efficiencies of about 25% and are much smaller and lighter than solid-state lasers. However, they can only emit good beam quality at lower peak powers, which has so far prevented them from being used in spaceborne lidar applications. In this paper, we assess whether the novel lidar modalities necessitated by these lower peak powers are suitable for satellite lidar, determined by whether they can match the design performance of GEDI by being able to accurately measure ground elevation through 98% canopy cover, referred to as having “98% beam sensitivity”. Through this, we show that a diode laser can be operated in pulse train or pulse compressed lidar (PCL) mode from space, using a photon-counting detector. In the best case scenario, this setup requires a detected energy of Edet=0.027 fJ to achieve a beam sensitivity of 98%, which is less than the 0.28 fJ required by a full-waveform solid-state lidar instrument, exemplified by GEDI. When also accounting for the higher laser and detector efficiency, the diode laser in pulse train mode requires similar shot energy as a photon counting solid-state laser such as ICESat-2 which along with the higher laser efficiency could result in a doubling of coverage. We conclude that there is a clear opportunity for diode lasers to be used in spaceborne lidars, potentially allowing wider coverage through their higher efficiencies

Influence of HAART on Alternative Reading Frame Immune Responses over the Course of HIV-1 Infection

Background: Translational errors can result in bypassing of the main viral protein reading frames and the production of alternate reading frame (ARF) or cryptic peptides. Within HIV, there are many such ARFs in both sense and the antisense directions of transcription. These ARFs have the potential to generate immunogenic peptides called cryptic epitopes (CE). Both antiretroviral drug therapy and the immune system exert a mutational pressure on HIV-1. Immune pressure exerted by ARF CD8(+) T cells on the virus has already been observed in vitro. HAART has also been described to select HIV-1 variants for drug escape mutations. Since the mutational pressure exerted on one location of the HIV-1 genome can potentially affect the 3 reading frames, we hypothesized that ARF responses would be affected by this drug pressure in vivo. Methodology/Principal findings: In this study we identified new ARFs derived from sense and antisense transcription of HIV-1. Many of these ARFs are detectable in circulating viral proteins. They are predominantly found in the HIV-1 env nucleotide region. We measured T cell responses to 199 HIV-1 CE encoded within 13 sense and 34 antisense HIV-1 ARFs. We were able to observe that these ARF responses are more frequent and of greater magnitude in chronically infected individuals compared to acutely infected patients, and in patients on HAART, the breadth of ARF responses increased. Conclusions/Significance: These results have implications for vaccine design and unveil the existence of potential new epitopes that could be included as vaccine targets.International AIDS Vaccine Initiative (IAVI

Measurement of the effective weak mixing angle by jet-charge asymmetry in hadronic decays of the Z boson

The coupling of the Z boson to quarks is studied in a sample of about 3.5 million hadronic Z decays collected by the L3 experiment at LEP from 1991 to 1995. The forward-backward quark charge asymmet ry is measured by means of a jet charge technique. From the measured asymmetries, the effective weak mixing angle is determined to be \begin{center} $\STE = 0.2327 \pm 0.0012(\mbox{\emph{stat.}} ) \pm 0.0013(\mbox{\emph{syst.}}).

Measurement of the inclusive charmless semileptonic branching fraction of beauty hadrons and a determination of |VubV_{ub}| at LEP

A measurement of the inclusive charmless semileptonic branching fraction of beauty hadrons, $\mathrm{b}\rightarrow\mathrm{X}_\mathrm{u }\ell\nu$, has been performed using almost two million hadronic Z decays collected by the L3 experiment at LEP, yielding the result: \begin{displaymath} \mathrm{Br}(\mathrm{b}\rightarrow\mathrm{X}_\mathr m{u}\ell\nu) = (3.3 \pm 1.0 \pm 1.7)\times 10^{-3}. \end{displaymath} The first uncertainty is statistical and the second is systematic. The modulus of the Cabibbo-Kobayashi-Maskawa matrix element $\mathrm{V_{ub}}$ extracted from this measurement is: \begin{displaymath} |\mathrm{V_{ub}}| = (6.0\, ^{+0.8}_{-1.0} \, ^{+1.4}_{-1.9} \pm 0.2)\times 10^{-3}, \end{displaymath} where the uncertainties are statistical, systematic and theoretical, respectively

Determination of the number of light neutrino species from single photon production at LEP

A determination of the number of light neutrino families performed by measuring the cross section of single photon production in \ee\ collision near the \Zo\ resonance is reported. From an integrated luminosity of $100~\mathrm{pb^{-1}}$, collected during the years 1991--94, we have observed 2091 single photon candidates with an energy above 1~\GeV\ in the polar angular region $45^\circ < \theta_\gamma < 135^\circ$. From a maximum likelihood fit to the single photon cross section, the \Zo\ decay width into invisible particles is measured to be \Ginv = 498 \pm 12 \mathrm{(stat)} \pm 12 \mathrm{(sys)~MeV}. Using the Standard Model couplings of neutrinos to the \Zo, the number of light neutrino species is determined to be $N_\nu = 2.98 \pm 0.07 (\mathrm{stat}) \pm 0.07 (\mathrm{sys}).

Search for neutral B meson decays to two charged leptons

The decays $\mathrm{B_d^0,\,B_s^0 \rightarrow e^+e^-,\,\mu^+\mu^-,\, e^\pm\mu^\mp}$ are searched for in 3.5 million hadronic ${\mathrm{Z}}$ events, which constitute the full LEP I data sample collected by the L3 detector. No signals are observed, therefore upper limits at the 90\%(95\%) confidence levels are set on the following branching fractions: % \begin{center}% {\setlength{\tabcolsep}{2pt} \begin{tabular}{lccccclcccc}% % Br$({\mathrm{B_d^0 \rightarrow {\mathrm{e^+e^-}}}})$ & $<$ & $1.4(1.8)$ & $\times$ & $10^{-5}$; & \hspace*{5mm} & Br$({\mathrm{B_s^0 \rightarrow {\mathrm{e^+e^-}}}})$ & $<$ & $5.4(7.0)$ & $\times$ & $10^{-5}$; \\% Br$({\mathrm{B_d^0 \rightarrow \mu^+\mu^-}})$ & $<$ & $1.0(1.4)$ & $\times$ & $10^{-5}$; & \hspace*{5mm} & Br$({\mathrm{B_s^0 \rightarrow \mu^+\mu^-}})$ & $<$ & $3.8(5.1)$ & $\times$ & $10^{-5}$; \\% Br$({\mathrm{B_d^0 \rightarrow {\mathrm{e^\pm\mu^\mp}}}})$ & $<$ & $1.6(2.0)$ & $\times$ & $10^{-5}$; & \hspace*{5mm} & Br$({\mathrm{B_s^0 \rightarrow {\mathrm{e^\pm\mu^\mp}}}})$ & $<$ & $4.1(5.3)$ & $\times$ & $10^{-5}$. \\% % \end{tabular}% } \end{center}% % The results for ${\mathrm{B_s^0\rightarrow{\mathrm{e^+e^-}}}}$ and ${\mathrm{B_s^0 \rightarrow {\mathrm{e^\pm\mu^\mp}}}}$ are the first limits set on these decay modes