271 research outputs found
Dynamic Contact Angle on a Surface with Gradient in Wettability
The retention and drainage of water on heat exchangers is extremely important in air-conditioning, refrigeration, and heat-pumping systems. In this work, droplets of varying sizes sliding on an inclined heat exchanger materials with and without a wettability gradient are observed using a high-speed camera. The dynamic contact angles, the shape evolution and the velocity of the droplet are obtained by image processing. Aluminum and copper surfaces are examined and the gradient is created by partially treating the base surface. The hypothesis is that the momentum of a sliding droplet on a treated surface will push the droplet onto the part without any treatment, so that water retention and drainage can be improved with limited surface treatment. It is found that the dynamic contact angle, the shape evolution and the velocity can be very different for droplets sliding in a wettability-increasing direction when compared to those sliding in a wettability-decreasing direction. The results are very important for the design of specialized heat transfer surfaces operating under dehumidification or defrosting conditions
Optimal Harvest Control in a Singular Prey-Predator Fishery Model with Maturation Delay and Gestation Delay
This paper presents a singular prey-predator fishery model, where maturation delay for prey and gestation delay for predator are considered. Fishing efforts are introduced to harvest prey and predator population, which are developed as control instruments to investigate optimal utilization of fishery resource. By analyzing associated characteristic equation, local stability analysis is studied due to combined variations of double time delays. Furthermore, Pontryagin's maximum principle is utilized to characterize optimal harvest control, and the optimality system is numerically solved based on an iterative method
RF-Transformer: A Unified Backscatter Radio Hardware Abstraction
This paper presents RF-Transformer, a unified backscatter radio hardware
abstraction that allows a low-power IoT device to directly communicate with
heterogeneous wireless receivers at the minimum power consumption. Unlike
existing backscatter systems that are tailored to a specific wireless
communication protocol, RF-Transformer provides a programmable interface to the
micro-controller, allowing IoT devices to synthesize different types of
protocol-compliant backscatter signals sharing radically different PHY-layer
designs. To show the efficacy of our design, we implement a PCB prototype of
RF-Transformer on 2.4 GHz ISM band and showcase its capability on generating
standard ZigBee, Bluetooth, LoRa, and Wi-Fi 802.11b/g/n/ac packets. Our
extensive field studies show that RF-Transformer achieves 23.8 Mbps, 247.1
Kbps, 986.5 Kbps, and 27.3 Kbps throughput when generating standard Wi-Fi,
ZigBee, Bluetooth, and LoRa signals while consuming 7.6-74.2 less power than
their active counterparts. Our ASIC simulation based on the 65-nm CMOS process
shows that the power gain of RF-Transformer can further grow to 92-678. We
further integrate RF-Transformer with pressure sensors and present a case study
on detecting foot traffic density in hallways. Our 7-day case studies
demonstrate RFTransformer can reliably transmit sensor data to a commodity
gateway by synthesizing LoRa packets on top of Wi-Fi signals. Our experimental
results also verify the compatibility of RF-Transformer with commodity
receivers. Code and hardware schematics can be found at:
https://github.com/LeFsCC/RF-Transformer
Managing health risks of perfluoroalkyl acids in aquatic food from a river-estuary-sea environment affected by fluorochemical industry
Substantial perfluoroalkyl acids (PFAAs) production still occurs in China, and the consumption of aquatic products is a critical exposure pathway of PFAAs in humans. In this study, specimens of 16 freshwater and 40 marine species were collected in the river-estuary-sea environment affected by a mega fluorochemical industry park in China in 2015, and the edible tissues of these organisms were analyzed for PFAA levels. Perfluorooctanoic acid (PFOA) was the dominating contaminant with an overall contribution of more than 90%, and concentrations as high as 2161 ng/g wet weight (measured in the freshwater winkle). All species with the greatest PFOA levels were benthic. The trophic magnification factor (TMF) of PFOA was 1.10 for freshwater species and 1.28 for marine species, indicating that PFOA was slightly magnifying. Analysis of carbon source indicated that freshwater species were more benthic feeding, while marine species were more pelagic feeding. Aquatic food consumption screening values of PFOA were modified according to estimated daily intake (EDI) values, which generated recommendations for limited meal categories and the do-not-eat category. Thus, this study provides recommendations for mitigating the health risks of PFAA-contaminated aquatic food, ranging from food selection to consumption frequency and proper food processing
Bacteria capable of degrading anthracene, phenanthrene, and fluoranthene as revealed by DNA based stable-isotope probing in a forest soil
Information on microorganisms possessing the ability to metabolize different polycyclic aromatic hydrocarbons (PAHs) in complex environments helps in understanding PAHs behavior in natural environment and developing bioremediation strategies. In the present study, stable-isotope probing (SIP) was applied to investigate degraders of PAHs in a forest soil with the addition of individually 13C-labeled phenanthrene, anthracene, and fluoranthene. Three distinct phylotypes were identified as the active phenanthrene-, anthracene- and fluoranthene-degrading bacteria. The putative phenanthrene degraders were classified as belonging to the genus Sphingomona. For anthracene, bacteria of the genus Rhodanobacter were the putative degraders, and in the microcosm amended with fluoranthene, the putative degraders were identified as belonging to the phylum Acidobacteria. Our results from DNA-SIP are the first to directly link Rhodanobacter- and Acidobacteria-related bacteria with anthracene and fluoranthene degradation, respectively. The results also illustrate the specificity and diversity of three- and four-ring PAHs degraders in forest soil, contributes to our understanding on natural PAHs biodegradation processes, and also proves the feasibility and practicality of DNA-based SIP for linking functions with identity especially uncultured microorganisms in complex microbial biota
Direct conversion of astrocytes into neuronal cells by drug cocktail
Direct conversion of astrocytes into neuronal cells by
drug cocktail
Cell Research advance online publication 2 October 2015; doi:10.1038/cr.2015.120
Dear Editor,
Neurological disorder is one of the greatest threats
to public health according to the World Health Organization.
Because neurons have little or no regenerative
capacity, conventional therapies for neurological disorders
yielded poor outcomes. While the introduction of
exogenous neural stem cells or neurons holds promise,
many challenges still need to be tackled, including cell
resource, delivery strategy, cell integration and cell
maturation. Reprogramming of fibroblasts into induced
pluripotent stem cells or directly into desirable neuronal
cells by transcription factors (TFs) or small molecules
can solve some problems, but other issues remain to be
addressed, including safety, conversion efficiency and
epigenetic memory [1, 2].
Astrocytes are considered to be the ideal starting
candidate cell type for generating new neurons, due to
their proximity in lineage distance to neurons and ability
to proliferate after brain damage. Many studies have
already revealed that astrocytes of the central nervous
system can be reprogrammed into induced neuronal cells
by virus-mediated overexpression of specific TFs in vitro
and in vivo [3-6]. However, application of this virus-mediated
direct conversion is still limited due to concerns
on clinical safety. We have previously reported direct
conversion of somatic cells into neural progenitor cells
(NPCs) in vitro by cocktail of small molecules under hypoxia
[7]. Here we set out to explore whether astrocytes
can be induced into neuronal cells by the chemical cocktail
in vitro
Redox-sensitive Pluronic F127-tocopherol micelles: synthesis, characterization, and cytotoxicity evaluation
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