A Fast Splitting Method for efficient Split Bregman Iterations

In this paper we propose a new fast splitting algorithm to solve the Weighted Split Bregman minimization problem in the backward step of an accelerated Forward-Backward algorithm. Beside proving the convergence of the method, numerical tests, carried out on different imaging applications, prove the accuracy and computational efficiency of the proposed algorithm

Photon-assisted shot noise in graphene in the Terahertz range

When subjected to electromagnetic radiation, the fluctuation of the electronic current across a quantum conductor increases. This additional noise, called photon-assisted shot noise, arises from the generation and subsequent partition of electron-hole pairs in the conductor. The physics of photon-assisted shot noise has been thoroughly investigated at microwave frequencies up to 20 GHz, and its robustness suggests that it could be extended to the Terahertz (THz) range. Here, we present measurements of the quantum shot noise generated in a graphene nanoribbon subjected to a THz radiation. Our results show signatures of photon-assisted shot noise, further demonstrating that hallmark time-dependant quantum transport phenomena can be transposed to the THz range.Comment: includes supplemental materia

A green prospective for learned post-processing in sparse-view tomographic reconstruction

Deep Learning is developing interesting tools that are of great interest for inverse imaging applications. In this work, we consider a medical imaging reconstruction task from subsampled measurements, which is an active research field where Convolutional Neural Networks have already revealed their great potential. However, the commonly used architectures are very deep and, hence, prone to overfitting and unfeasible for clinical usages. Inspired by the ideas of the green AI literature, we propose a shallow neural network to perform efficient Learned Post-Processing on images roughly reconstructed by the filtered backprojection algorithm. The results show that the proposed inexpensive network computes images of comparable (or even higher) quality in about one-fourth of time and is more robust than the widely used and very deep ResUNet for tomographic reconstructions from sparse-view protocols

EVALUASI DAN ANALISIS PROGRAM KEMITRAAN KONSERVASI DI TAMAN NASIONAL BUNAKEN DALAM PENGELOLAAN EKOSISTEM TERUMBU KARANG DI DESA POOPOH KABUPATEN MINAHASA

This study aimed to evaluate the conservation partnership program comprehensively and the factors that affect the achievement of the program inside and outside society related with the programs. This research used a combination of qualitative and quantitative methods in a dominant-less dominant design which was analyzed descriptively. The results showed that conservation partnership program already meets the expectations and needs of the community. In environment aspects shows that cover of coral reefs at the conservation partnership site is in moderate condition (35.28%) if compared to the condition of coral reefs outside the conservation partnership site which is in bad condition (18.25%). 266 fish were found on conservation partnership site, while only 187 fish found in off-site conservation partnership. In economic perspective, there are an increase in people. In social point, the existence of this conservation partnership program has raised awareness of the importance of coral reef ecosystems. From internal factors, the need for financial aid is essential to encourage people to start the conservation partnership program, while in external factors, better regulation from the local government will motivate people to join the program

Esophageal Varices Bleeding in Portal Hypertension Due to Portal Vein and Splenic Vein Obstruction

Based on its relation to the liver sinusoid, increased pressure of portal vein can occur at three levels: presinusoid, sinusoid ,and postsinusoid. Obstruction of the presinusoid veins can be caused by extra- hepatic condition such as venous thrombosis. We reported a case of portal hypertension with esophageal varices bleeding was a result of obstruction due to thrombosis of the splenic vein and portal vein under hypercoagulant conditions due to thrombocytosis. The management of esophageal varices was sclerotherapy while for overcome the thrombosis the patient was given hydroxy urea

Mitotane concentrations influence outcome in patients with advanced adrenocortical carcinoma

Mitotane is the main option of treatment for advanced adrenocortical carcinoma (ACC). However, limited evidence is available regarding the impact of plasma mitotane levels on patient outcome. To address this question, we retrospectively analyzed patients with advanced ACC treated with mitotane for 653 months, with 653 measurements of plasma mitotane reported in the Lysosafe Online\uae database (HRA Pharma, France), followed at 12 tertiary centers in Italy from 2005 to 2017. We identified 80 patients, initially treated with mitotane alone (56.2%) or plus chemotherapy (43.8%). The preference toward combination therapy was given to de novo stage IV ACC and younger patients. After the first line of treatment, 25% of valid cases experienced clinical benefit (14.5% objective response, 10.5% stabilization of disease) and 75% progression, without differences between the groups of treatment. Patients with progression had a lower time in the target range (TTR) of plasma mitotane and an unfavorable outcome. Death occurred in 76.2% of cases and multivariate analysis showed that clinical benefit after first treatment and longer TTR were favorable predictors of overall survival (OS). In conclusion, the present findings support the importance of mitotane monitoring and strengthen the concept of a therapeutic window for mitotane

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria

Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm. The outer membrane contains various protein channels, called porins, which are involved in the influx of various compounds, including several classes of antibiotics. Bacterial adaptation to reduce influx through porins is an increasing problem worldwide that contributes, together with efflux systems, to the emergence and dissemination of antibiotic resistance. An exciting challenge is to decipher the genetic and molecular basis of membrane impermeability as a bacterial resistance mechanism. This Review outlines the bacterial response towards antibiotic stress on altered membrane permeability and discusses recent advances in molecular approaches that are improving our knowledge of the physico-chemical parameters that govern the translocation of antibiotics through porin channel