566 research outputs found

    Memory of Water Scenic Design-- Reinventing Memories on Stage

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    My paper describes my process of designing the set for the UNH Theatre and Dance Department production The Memory of Water. Linking dream and reality together, the set design of the show is my attempt and process of putting the non-realistic elements into a more tangible form-- reinventing the memories on the stage

    Effects of transforming growth factor β on β1 integrin expression and localization during myogenesis in chicken

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    Myoblast-extracellular environment interactions are mediated by the integrin family of cell adhesion receptors. Integrins have been shown to play a pivotal role in skeletal muscle development. The β1 integrin has been shown to play a critical role in muscle cell attachment, migration and the formation of multinucleated myotubes. Transforming growth factor β (TGF-β) is a potent inhibitor of both skeletal muscle myoblast proliferation and differentiation. The expression of TGF-β will affect cell β1 integrin expression and localization. The chicken genetic muscle weakness, Low Score Normal (LSN), exhibits modified myotube and sarcomere structure, and increase TGF-β and reduced β1 integrin expression during myogenesis. The current study used LSN satellite cells, myogenic precursor cells, as a model to further investigate the role of TGF-β and β1 integrin during myogenesis, compared to normal satellite cells. The LSN satellite cells have elevated expression of TGF-β and decreased β1 integrin during proliferation and differentiation. The β1 integrin was localized at areas of cell–cell contact in normal cells, whereas in LSN satellite cell cultures β1 integrin was observed within cells. The addition of the exogenous TGF-β in normal cell cultures decreased both β1 integrin mRNA and protein expression at 24 and 48 h of differentiation. The localization of β1 integrin was altered also, from areas of cell-cell contact to inside cells. These data suggest that TGF-β may play a pivotal role in myogenesis through modulation of the expression and localization of β1 integrin which is important in the control of cell migration and growth regulation

    2-Hydroxy-N,N′-diisopropylpropane-1,3-diaminium dichloride

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    In the crystal structure of the title amino alcohol derivative, C9H24N2O2+·2Cl−, the cations and anions are linked by inter­molecular O—H⋯Cl and N—H⋯Cl hydrogen bonds into a three-dimensional network

    Periodic Oscillations in a Chemostat Model with Two Discrete Delays

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    Periodic oscillations of solutions of a chemostat-type model in which a species feeds on a limiting nutrient are considered. The model incorporates two discrete delays representing the lag in nutrient recycling and nutrient conversion. Through the study of characteristic equation associated with the linearized system, a unique positive equilibrium is found and proved to be locally asymptotically stable under some conditions. Meanwhile, a Hopf bifurcation causing periodic solutions is also obtained. Numerical simulations illustrate the theoretical results

    A saturated genetic linkage map of autotetraploid alfalfa (Medicago sativa L.) developed using genotyping-by-sequencing is highly syntenous with the Medicago truncatula genome.

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    A genetic linkage map is a valuable tool for quantitative trait locus mapping, map-based gene cloning, comparative mapping, and whole-genome assembly. Alfalfa, one of the most important forage crops in the world, is autotetraploid, allogamous, and highly heterozygous, characteristics that have impeded the construction of a high-density linkage map using traditional genetic marker systems. Using genotyping-by-sequencing (GBS), we constructed low-cost, reasonably high-density linkage maps for both maternal and paternal parental genomes of an autotetraploid alfalfa F1 population. The resulting maps contain 3591 single-nucleotide polymorphism markers on 64 linkage groups across both parents, with an average density of one marker per 1.5 and 1.0 cM for the maternal and paternal haplotype maps, respectively. Chromosome assignments were made based on homology of markers to the M. truncatula genome. Four linkage groups representing the four haplotypes of each alfalfa chromosome were assigned to each of the eight Medicago chromosomes in both the maternal and paternal parents. The alfalfa linkage groups were highly syntenous with M. truncatula, and clearly identified the known translocation between Chromosomes 4 and 8. In addition, a small inversion on Chromosome 1 was identified between M. truncatula and M. sativa. GBS enabled us to develop a saturated linkage map for alfalfa that greatly improved genome coverage relative to previous maps and that will facilitate investigation of genome structure. GBS could be used in breeding populations to accelerate molecular breeding in alfalfa

    Pricing decision research for TPL considering different logistics service level influencing the market demand

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    Purpose: With the rapid development of economy and the support of government policy, the development of the logistics industry has become a new economic growth engine. As we all know, the reasonable price of logistics service is the most critical factor for logistics enterprises to win market share and make profit. At the same time, the service level is one of the most important factors which will influence the size of the market share. Therefore, this paper constructs a pricing model considering a situation that the logistics service level affects the market demand. This model helps the enterprises to make scientific decisions. Methodology: To achieve this objective, this paper constructs the TPL service and the pricing decision models based on the game theory. Findings: The conclusion shows that under the situation of independent decision-making, the enterprise which has strong ability of logistics service does not necessarily have a competitive advantage, while pricing equilibrium under the situation of joint decision-making, not only make both sides get more income, but also be conducive to improve the level of service. Research limitations: In this research, there are some assumptions that might affect the accuracy the model such as there are only two TPL enterprises to participate in, and considerations are taken under the condition of complete information environment. These assumptions can be relaxed in the future work. Originality: In this research, logistics service level is taken account into the areas of logistics service pricing, which makes the models more practical and more perfect. And this paper constructs game models based on game theory to make up the limitations of traditional pricing theories in logistics service pricing.Peer Reviewe

    Study on Nano-Silica in Protection of Paper

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    In this work , the role of nano-silica in protection of paper works were investigated. Nano-silica was used as protective coating on the surface of the paper. To prove the protective of this coating, the mechanical properties and the ultraviolet absorption of paper were measured, such as tensile strength, folding endurance, tear strength, the glossiness and brightness of paper. The results show that the tensile strength and the folding endurance of paper coated with nano-silica have increased, the tear strength of paper coated with nano-silica has dicrease, and the glossiness and brightness remained unchanged. The paper coated by nano-silica has strong absorption peaks for ultraviolet radiation from 200 nm to 300 nm. &nbsp

    1-(Isopropyl­amino)-3-phen­oxy­propan-2-ol

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    In the crystal structure of the title amino alcohol derivitive, C12H19NO2, mol­ecules are linked by N—H⋯O hydrogen bonds. The mol­ecular structure exhibits an intra­molecular O—H⋯N hydrogen bond

    Factors Affecting Consultation Volume in an Online Healthcare Community: Evidence from Online Data in China

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    Under the background of sharing economy, online healthcare has been developing rapidly to ease the pressure of offline medical care. The interaction between doctors and patients is the key element of the sustainable development of online healthcare communities. To explore the influence of doctors\u27 online word-of-mouth, online vitality and consulting service price on consultation volume, we build a multiple regression model taking consultation volume as the dependent variable, online word-of-mouth and online vitality and consulting service price as independent variables. By analyzing the data of 37,977 doctors collected from the online healthcare community, we find that doctors\u27 online word-of-mouth and online vitality have significant positive impacts on consultation volume. Our results also show that there is an inverted U-shaped relationship between consulting service price and consultation volume, and online word-of-mouth has a greater impact on consultation volume than any other factors. Finally, we put forward suggestions for doctors in online healthcare communities
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