16 research outputs found
Human cellular restriction factors that target HIV-1 replication
Recent findings have highlighted roles played by innate cellular factors in restricting intracellular viral replication. In this review, we discuss in brief the activities of apolipoprotein B mRNA-editing enzyme 3G (APOBEC3G), bone marrow stromal cell antigen 2 (BST-2), cyclophilin A, tripartite motif protein 5 alpha (Trim5α), and cellular microRNAs as examples of host restriction factors that target HIV-1. We point to countermeasures encoded by HIV-1 for moderating the potency of these cellular restriction functions
1,2,3-triazolin-5-ylidenes: Synthesis of hetero-bis(carbene) Pd(II) complexes, determination of donor strengths, and catalysis
10.1021/om2010029Organometallics311405-412ORGN