Transition‐Metal‐Free Cross‐Coupling of Benzothiophenes and Styrenes in a Stereoselective Synthesis of Substituted (E,Z)‐1,3‐Dienes

A transition metal‐free one‐pot stereoselective approach to substituted (E,Z)‐1,3‐dienes was developed by using an interrupted Pummerer reaction/ligand‐coupling strategy. Readily available benzothiophene S‐oxides, which can be conveniently prepared by oxidation of the parent benzothiophenes, undergo Pummerer coupling with styrenes. Reaction of the resultant sulfonium salts with alkyllithium/magnesium reagents generates underexploited hypervalent sulfurane intermediates that undergo selective ligand coupling, resulting in dismantling of the benzothiophene motif and the formation of decorated (E,Z)‐1,3‐dienes

Palladium Catalysed Heck Reactions of Alk-1-en-3-ones with Aryl Bromides: A Very Simple Access to (E)-1-Arylalk-1-en-3-ones

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Direct arylation of thiophenes via palladium-catalyzed C–H functionalisation at low catalyst loadings

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Palladium-catalyzed direct arylation of furans via C-H functionalisation at low catalyst loadings

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Heck Arylations of Pent-4-enoates or Allylmalonate using a Palladium/Tetraphosphine Catalyst

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Heck reactions of Α- or Β-substituted enol ethers with aryl bromides catalysed by a tetraphosphine/palladium complex. A direct access to acetophenone or 1-arylpropanone derivatives

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Palladium/tetraphosphine catalyzed Heck reaction of vinyl bromides with alkenes: a powerful access to conjugated dienes

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