112 research outputs found
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Utilizing Mobile Phones for Payment
This study introduces a sound-based mobile payment system. Using a mobile phone for payment for mobile commerce is essential for its success. The proposed system will use sound that is generated from the existing mobile phone and the sound can be recognized by the existing credit card reader of the shop with an installation of an ordinary microphone and simple software to process sound input. This system is a better system since it doesn\u27t require customers to buy a new mobile phone and the cost for the microphone and the software is very low
Creative integration of design thinking and strategic thinking in a design education framework
With rapid globalization, designers are increasingly required to use creative integration of strategic thinking and design thinking to deal with complexity and uncertainty in an era of constant transformation. This study reviews the current status of design education to address the key question of how strategic thinking and design thinking can be enhanced creatively in undergraduate design students’ education in South Korea. Furthermore, it investigates the key drivers for and barriers to the enhancement of strategic thinking and design thinking; seeks insights from successful design education programs; and gathers perspectives about strategic thinking and design thinking from design students, educators, and strategists. By using qualitative (in-depth interviews) and quantitative (a questionnaire) research methods, the study offers significant insights: (i) design undergraduates’ short-sighted mind-set should be reshaped, (ii) additional practical, multicultural, and interdisciplinary applications of strategic thinking are needed to bridge the gap between theoretical and practical classes, and (iii) consistent stimulation is required to internalize strategic thinking and design thinking
Analysis of several VERA benchmark problems with the photon transport capability of STREAM
STREAM - a lattice transport calculation code with method of characteristics for the purpose of light water reactor analysis - has been developed by the Computational Reactor Physics and Experiment laboratory (CORE) of the Ulsan National Institute of Science and Technology (UNIST). Recently, efforts have been taken to develop a photon module in STREAM to assess photon heating and the influence of gamma photon transport on power distributions, as only neutron transport was considered in previous STREAM versions. A multi-group photon library is produced for STREAM based on the ENDF/B-VII.1 library with the use of the library-processing code NJOY. The developed photon solver for the computation of 2D and 3D distributions of photon flux and energy deposition is based on the method of characteristics like the neutron solver. The photon library and photon module produced and implemented for STREAM are verified on VERA pin and assembly problems by comparison with the Monte Carlo code MCS - also developed at UNIST. A short analysis of the impact of photon transport during depletion and thermal hydraulics feedback is presented for a 2D core also from the VERA benchmark. (C) 2022 Korean Nuclear Society, Published by Elsevier Korea LLC
PONDEROSA, an automated 3D-NOESY peak picking program, enables automated protein structure determination
Summary: PONDEROSA (Peak-picking Of Noe Data Enabled by Restriction of Shift Assignments) accepts input information consisting of a protein sequence, backbone and sidechain NMR resonance assignments, and 3D-NOESY (13C-edited and/or 15N-edited) spectra, and returns assignments of NOESY crosspeaks, distance and angle constraints, and a reliable NMR structure represented by a family of conformers. PONDEROSA incorporates and integrates external software packages (TALOS+, STRIDE and CYANA) to carry out different steps in the structure determination. PONDEROSA implements internal functions that identify and validate NOESY peak assignments and assess the quality of the calculated three-dimensional structure of the protein. The robustness of the analysis results from PONDEROSA's hierarchical processing steps that involve iterative interaction among the internal and external modules. PONDEROSA supports a variety of input formats: SPARKY assignment table (.shifts) and spectrum file formats (.ucsf), XEASY proton file format (.prot), and NMR-STAR format (.star). To demonstrate the utility of PONDEROSA, we used the package to determine 3D structures of two proteins: human ubiquitin and Escherichia coli iron-sulfur scaffold protein variant IscU(D39A). The automatically generated structural constraints and ensembles of conformers were as good as or better than those determined previously by much less automated means
PONDEROSA-C/S: client–server based software package for automated protein 3D structure determination
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A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation
The following corrections appear in the attached pdf labelled "Correction to Version of Record". The authors inadvertently omitted Woonghee Lee from the list of authors. The corrected author list and affiliations are noted. Revised acknowledgment paragraphs including Woonghee Lee’s funding source and contribution also appear in the correction.
In addition, the authors noted the omission of details of NMR structure calculation from the Materials and Methods section. The relevant paragraph and the references associated with it are appended.Eukaryotic ribosome biogenesis involves ∼200 assembly factors, but how these contribute to ribosome maturation is poorly understood. Here, we identify a network of factors on the nascent 60S subunit that actively remodels preribosome structure. At its hub is Rsa4, a direct substrate of the force-generating ATPase Rea1. We show that Rsa4 is connected to the central protuberance by binding to Rpl5 and to ribosomal RNA (rRNA) helix 89 of the nascent peptidyl transferase center (PTC) through Nsa2. Importantly, Nsa2 binds to helix 89 before relocation of helix 89 to the PTC. Structure-based mutations of these factors reveal the functional importance of their interactions for ribosome assembly. Thus, Rsa4 is held tightly in the preribosome and can serve as a “distribution box,” transmitting remodeling energy from Rea1 into the developing ribosome. We suggest that a relay-like factor network coupled to a mechano-enzyme is strategically positioned to relocate rRNA elements during ribosome maturation
A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation
Eukaryotic ribosome biogenesis involves ∼200 assembly factors, but how these contribute to ribosome maturation is poorly understood. Here, we identify a network of factors on the nascent 60S subunit that actively remodels preribosome structure. At its hub is Rsa4, a direct substrate of the force-generating ATPase Rea1. We show that Rsa4 is connected to the central protuberance by binding to Rpl5 and to ribosomal RNA (rRNA) helix 89 of the nascent peptidyl transferase center (PTC) through Nsa2. Importantly, Nsa2 binds to helix 89 before relocation of helix 89 to the PTC. Structure-based mutations of these factors reveal the functional importance of their interactions for ribosome assembly. Thus, Rsa4 is held tightly in the preribosome and can serve as a “distribution box,” transmitting remodeling energy from Rea1 into the developing ribosome. We suggest that a relay-like factor network coupled to a mechano-enzyme is strategically positioned to relocate rRNA elements during ribosome maturation
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