369 research outputs found
Comparison of the stand-alone Cox-Maze IV procedure to the concomitant Cox-Maze IV and mitral valve procedure for atrial fibrillation
BACKGROUND: The majority of patients undergoing surgical ablation for atrial fibrillation (AF) worldwide receive a concomitant mitral valve (MV) procedure. This study compared outcomes of the Cox-Maze IV (CMIV) in patients with lone AF to those with AF and MV disease. METHODS: A retrospective review of 335 patients receiving either a stand-alone CMIV for AF (n=151) or a CMIV with a MV procedure (n=184) was performed from January 2002 through December of 2012. Data were obtained at 3, 6, 12, 24, and 48 months and patients were evaluated for recurrence of AF. Twenty-four preoperative and perioperative variables were evaluated to identify predictors of AF recurrence at one year. RESULTS: The two groups differed in that stand-alone CMIV patients were younger, had AF of longer duration and had more failed catheter ablations, while patients with AF and MV disease had larger left atria and worse New York Heart Association class (P≤0.001). Operative mortality was higher in the concomitant MV group (1% vs. 5%, P=0.015). Freedom from AF and antiarrhythmic drugs at 12 and 24 months were similar between the two groups (73% and 76% at 12 months; 77% vs. 78% at 24 months). Predictors of recurrence included failure to use a box-lesion to isolate the pulmonary veins and posterior left atria, early recurrence of atrial tachyarrhythmias (ATAs) and the presence of a preoperative pacemaker (P=0.001). CONCLUSIONS: The efficacy of the CMIV procedure was similar in patients with and without co-existent MV pathology. Patients receiving a concomitant CMIV and MV procedure represented an older and sicker patient population and had higher mortality rates than those receiving a stand-alone CMIV procedure
The risk of telling : a dyadic perspective on romantic partners' responses to child sexual abuse disclosure and their associations with sexual and relationship satisfaction
Essai présenté à la Faculté des arts et des sciences en vue de l'obtention du grade de Doctorat en psychologie clinique (D. Psy.)Les survivants d’agression sexuelle à l’enfance (ASE) doivent souvent composer avec les conséquences à long terme de ce trauma. Toutefois, il existe une grande variabilité quant aux impacts individuels de l’ASE. Certains auteurs croient que la réponse obtenue lors du dévoilement de l’ASE aux proches du survivant, pourrait être l’un des déterminants de cette variabilité. Cependant, le dévoilement à l’âge adulte, notamment au partenaire amoureux, a été peu étudié. La présente étude examine les associations entre les réponses des partenaires amoureux au dévoilement, tels que perçues par les survivants, ainsi que la satisfaction sexuelle et conjugale des deux membres du couple, auprès d’un échantillon de 70 couples de la communauté ayant rapporté une ASE et l’ayant dévoilée à leur partenaire. Les participants ont complété des questionnaires auto-rapportés en ligne. Les résultats d’analyses de trajectoire au sein d’un modèle « Actor-Partner Interdependence Model » (APIM) indiquent que les réponses de « soutien émotionnel » de la part des partenaires durant le dévoilement, telles que perçues par les survivants, étaient positivement associées à leur propre satisfaction sexuelle ainsi qu’à celle de leur partenaire. Les réponses de « stigmatisation/se sentir traité différemment » de la part des partenaires, telles que perçues par les survivants, étaient associées à une moins bonne satisfaction conjugale, à la fois pour les survivants et leurs partenaires. Les résultats suggèrent que les réponses des partenaires au dévoilement d’une ASE, tels que perçues par les survivants, peuvent avoir un impact positif autant que négatif sur la satisfaction conjugale et sexuelle des deux partenaires.Survivors of childhood sexual abuse (CSA) often experience adverse trauma-related long term consequences, which vary widely among survivors. Some authors argued that this variability might be explained in part by the response of others to survivors’ disclosure of the CSA. However, disclosure during adulthood has received little empirical attention, in particular, disclosure to a romantic partner. Among 70 community couples who reported CSA and disclosure to their partner, this study examined associations between survivors’ perception of partner responses to their disclosure, and both partners’ sexual and relationship satisfaction. Participants completed self-report questionnaires online. Results of path analyses within an actor-partner interdependence model indicated that survivors’ perceived partner responses of emotional support to disclosure were associated with their own and their partners' higher sexual satisfaction. Survivors’ perceived responses of being stigmatized/treated differently by the partner were associated with their own and their partners’ poorer relationship satisfaction. Findings suggest that survivor-perceived partner responses to the disclosure of CSA can have both a positive and a negative impact on the sexual and relationship satisfaction of both partners
Resource dedication problem in a multi-project environment
There can be different approaches to the management of resources within
the context of multi-project scheduling problems. In general, approaches to multiproject scheduling problems consider the resources as a pool shared by all projects. On the other hand, when projects are distributed geographically or sharing resources between projects is not preferred, then this resource sharing policy may not be feasible. In such cases, the resources must be dedicated to individual projects throughout the project durations. This multi-project problem environment is defined here as the resource dedication problem (RDP). RDP is defined as the optimal dedication of resource capacities to different projects within the overall limits of the resources and with the objective of minimizing a predetermined objective function. The projects involved are multi-mode resource constrained project scheduling problems with finish to start zero time lag and non-preemptive activities and limited renewable and nonrenewable resources. Here, the characterization of RDP, its mathematical formulation and two different solution methodologies are presented. The first solution approach is a genetic algorithm employing a new improvement move called combinatorial auction for RDP, which is based on preferences of projects for resources. Two different methods for calculating the projects’ preferences based on linear and Lagrangian relaxation are proposed. The second solution approach is a Lagrangian relaxation based heuristic employing subgradient optimization. Numerical studies demonstrate that the proposed approaches are powerful methods for solving this problem
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