524 research outputs found
Social infrastructure: why it matters and how urban geographers might study it
Social infrastructure is an emerging research frontier in urban geography and urban studies. This editorial introduction provides a concise introduction to the term. It briefly sets out the intellectual provenance of the concept of social infrastructure, examining the different ways social infrastructure is being used across urban geography
Signal processing and machine learning techniques for Doppler ultrasound haemodynamic measurements
Haemodynamic monitoring is an invaluable tool for evaluating, diagnosing and treating
the cardiovascular system, and is an integral component of intensive care units, obstetrics
wards and other medical units. Doppler ultrasound provides a non-invasive, cost-effective
and fast means of haemodynamic monitoring, which traditionally necessitates highly invasive
methods such as Pulmonary artery catheter or transoesophageal echocardiography.
However, Doppler ultrasound scan acquisition requires a highly experienced operator and
can be very challenging. Machine learning solutions that quantify and guide the scanning
process in an automatic and intelligent manner could overcome these limitations and lead
to routine monitoring. Development of such methods is the primary goal of the presented
work.
In response to this goal, this thesis proposes a suite of signal processing and machine
learning techniques. Among these is a new and real-time method of maximum frequency
envelope estimation. This method, which is based on image-processing techniques and is
highly adaptive to varying signal quality, was developed to facilitate automatic and consistent
extraction of features from Doppler ultrasound measurements. Through a thorough
evaluation, this method was demonstrated to be accurate and more stable than alternative
state-of-art methods.
Two novel real-time methods of beat segmentation, which operate using the maximum
frequency envelope, were developed to enable systematic feature extraction from individual
cardiac cycles. These methods do not require any additional hardware, such as an electrocardiogram
machine, and are fully automatic, real-time and highly resilient to noise.
These qualities are not available in existing methods. Extensive evaluation demonstrated
the methods to be highly successful.
A host of machine learning solutions were analysed, designed and evaluated. This led to a set of novel features being proposed for Doppler ultrasound analysis. In addition, a state of-
the-art image recognition classification method, hitherto undocumented for Doppler
ultrasound analysis, was shown to be superior to more traditional modelling approaches.
These contributions facilitated the design of two innovative types of feedback. To reflect
beneficial probe movements, which are otherwise difficult to distinguish, a regression model
to quantitatively score ultrasound measurements was proposed. This feedback was shown
to be highly correlated with an ideal response.
The second type of feedback explicitly predicted beneficial probe movements. This was
achieved using classification models with up to five categories, giving a more challenging
scenario than those addressed in prior disease classification work. Evaluation of these, for
the first time, demonstrated that Doppler scan information can be used to automatically
indicate probe position.
Overall, the presented work includes significant contributions for Doppler ultrasound
analysis, it proposes valuable new machine learning techniques, and with continued work,
could lead to solutions that unlock the full potential of Doppler ultrasound haemodynamic
monitoring
Recommended from our members
Kepler-4B: A Hot Neptune-Like Planet of A G0 Star Near Main-Sequence Turnoff
Early time-series photometry from NASA's Kepler spacecraft has revealed a planet transiting the star we term Kepler-4, at R.A. = 19(h)02(m)27.(s)68, delta = +50 degrees 08'08 '' 7. The planet has an orbital period of 3.213 days and shows transits with a relative depth of 0.87 x 10(-3) and a duration of about 3.95 hr. Radial velocity (RV) measurements from the Keck High Resolution Echelle Spectrometer show a reflex Doppler signal of 9.3(-1.9)(+1.1) m s(-1), consistent with a low-eccentricity orbit with the phase expected from the transits. Various tests show no evidence for any companion star near enough to affect the light curve or the RVs for this system. From a transit-based estimate of the host star's mean density, combined with analysis of high-resolution spectra, we infer that the host star is near turnoff from the main sequence, with estimated mass and radius of 1.223(-0.091)(+0.053) M(circle dot) and 1.487(-0.084)(+0.071) R(circle dot).We estimate the planet mass and radius to be {M(P), R(P)} = {24.5 +/- 3.8 M(circle plus), 3.99 +/- 0.21 R(circle plus)}. The planet's density is near 1.9 g cm(-3); it is thus slightly denser and more massive than Neptune, but about the same size.W. M. Keck FoundationNASA's Science Mission DirectorateAstronom
Kepler Observations of Transiting Hot Compact Objects
Kepler photometry has revealed two unusual transiting companions orbiting an
early A-star and a late B-star. In both cases the occultation of the companion
is deeper than the transit. The occultation and transit with follow-up optical
spectroscopy reveal a 9400 K early A-star, KOI-74 (KIC 6889235), with a
companion in a 5.2 day orbit with a radius of 0.08 Rsun and a 10000 K late
B-star KOI-81 (KIC 8823868) that has a companion in a 24 day orbit with a
radius of 0.2 Rsun. We infer a temperature of 12250 K for KOI-74b and 13500 K
for KOI-81b.
We present 43 days of high duty cycle, 30 minute cadence photometry, with
models demonstrating the intriguing properties of these object, and speculate
on their nature.Comment: 12 pages, 3 figures, submitted to ApJL (updated to correct KOI74
lightcurve
Discovery of the Transiting Planet Kepler-5B
We present 44 days of high duty cycle, ultra precise photometry of the 13th magnitude star Kepler-5 (KIC 8191672, T(eff) = 6300 K, log g = 4.1), which exhibits periodic transits with a depth of 0.7%. Detailed modeling of the transit is consistent with a planetary companion with an orbital period of 3.548460 +/- 0.000032 days and a radius of 1.431(-0.052)(+0.041) R(J). Follow-up radial velocity measurements with the Keck HIRES spectrograph on nine separate nights demonstrate that the planet is more than twice as massive as Jupiter with a mass of 2.114(-0.059)(+0.056) M(J) and a mean density of 0.894 +/- 0.079 g cm(-3).NASA's Science Mission DirectorateAstronom
Kepler-7b: A Transiting Planet with Unusually Low Density
We report the discovery and confirmation of Kepler-7b, a transiting planet
with unusually low density. The mass is less than half that of Jupiter, Mp =
0.43 Mj, but the radius is fifty percent larger, Rp = 1.48 Rj. The resulting
density, 0.17 g/cc, is the second lowest reported so far for an extrasolar
planet. The orbital period is fairly long, P = 4.886 days, and the host star is
not much hotter than the Sun, Teff = 6000 K. However, it is more massive and
considerably larger than the sun, Mstar = 1.35 Msun and Rstar = 1.84 Rsun, and
must be near the end of its life on the Main Sequence.Comment: 19 pages, 3 figure
Modeling Kepler transit light curves as false positives: Rejection of blend scenarios for Kepler-9, and validation of Kepler-9d, a super-Earth-size planet in a multiple system
Light curves from the Kepler Mission contain valuable information on the
nature of the phenomena producing the transit-like signals. To assist in
exploring the possibility that they are due to an astrophysical false positive,
we describe a procedure (BLENDER) to model the photometry in terms of a "blend"
rather than a planet orbiting a star. A blend may consist of a background or
foreground eclipsing binary (or star-planet pair) whose eclipses are attenuated
by the light of the candidate and possibly other stars within the photometric
aperture. We apply BLENDER to the case of Kepler-9, a target harboring two
previously confirmed Saturn-size planets (Kepler-9b and Kepler-9c) showing
transit timing variations, and an additional shallower signal with a 1.59-day
period suggesting the presence of a super-Earth-size planet. Using BLENDER
together with constraints from other follow-up observations we are able to rule
out all blends for the two deeper signals, and provide independent validation
of their planetary nature. For the shallower signal we rule out a large
fraction of the false positives that might mimic the transits. The false alarm
rate for remaining blends depends in part (and inversely) on the unknown
frequency of small-size planets. Based on several realistic estimates of this
frequency we conclude with very high confidence that this small signal is due
to a super-Earth-size planet (Kepler-9d) in a multiple system, rather than a
false positive. The radius is determined to be 1.64 (+0.19/-0.14) R(Earth), and
current spectroscopic observations are as yet insufficient to establish its
mass.Comment: 20 pages in emulateapj format, including 8 tables and 16 figures. To
appear in ApJ, 1 January 2010. Accepted versio
A Transiting Hot Jupiter Orbiting a Metal-Rich Star
We announce the discovery of Kepler-6b, a transiting hot Jupiter orbiting a
star with unusually high metallicity, [Fe/H] = +0.34 +/- 0.04. The planet's
mass is about 2/3 that of Jupiter, Mp = 0.67 Mj, and the radius is thirty
percent larger than that of Jupiter, Rp = 1.32 Rj, resulting in a density of
0.35 g/cc, a fairly typical value for such a planet. The orbital period is P =
3.235 days. The host star is both more massive than the Sun, Mstar = 1.21 Msun,
and larger than the Sun, Rstar = 1.39 Rsun.Comment: 12 pages, 2 figures, submitted to the Astrophysical Journal Letter
- …