Особенности пролиферативных процессов при инвертированной папилломе и раке полости носа и околоносовых пазух

The article presents the results of investigation on detection of criterions of cell changing in inverted papilloma and carcinoma of the nasal cavity mucose and paranasal sinuses. Proliferative process in different layers of nasal cavity mucose and paranasal sinuses was examined by immunohistochemical method. It was established that the most important for diagnosis of inverted papilloma is proportion of cells in basal and parabasall layers. Carcinoma is characterized by distribution of positive painted cells from the basal membrane to the central zone of tumors.В статье представлены результаты исследования, направленного на выявление критериев изменений пролиферации клеток эпителия при инвертированной папилломе и раке слизистой оболочки полости носа и околоносовых пазух. С помощью иммуногистохимического метода была оценена пролиферация в различных слоях эпителия слизистой оболочки полости носа и околоносовых пазух. Установлено, что наиболее важным для диагностики инвертированных папиллом является соотношение пролиферирующих клеток в базальном и парабазальном клеточных слоях. В плоскоклеточном раке отмечена высокая пролиферативная активность клеток, архитектоника ткани была полностью нарушена и деление эпителия на слои практически отсутствовало. Положительно окрашенные клетки распределялись равномерно от базального слоя до центральной зоны опухоли

State of the climate in 2013

In 2013, the vast majority of the monitored climate variables reported here maintained trends established in recent decades. ENSO was in a neutral state during the entire year, remaining mostly on the cool side of neutral with modest impacts on regional weather patterns around the world. This follows several years dominated by the effects of either La Niña or El Niño events. According to several independent analyses, 2013 was again among the 10 warmest years on record at the global scale, both at the Earths surface and through the troposphere. Some regions in the Southern Hemisphere had record or near-record high temperatures for the year. Australia observed its hottest year on record, while Argentina and New Zealand reported their second and third hottest years, respectively. In Antarctica, Amundsen-Scott South Pole Station reported its highest annual temperature since records began in 1957. At the opposite pole, the Arctic observed its seventh warmest year since records began in the early 20th century. At 20-m depth, record high temperatures were measured at some permafrost stations on the North Slope of Alaska and in the Brooks Range. In the Northern Hemisphere extratropics, anomalous meridional atmospheric circulation occurred throughout much of the year, leading to marked regional extremes of both temperature and precipitation. Cold temperature anomalies during winter across Eurasia were followed by warm spring temperature anomalies, which were linked to a new record low Eurasian snow cover extent in May. Minimum sea ice extent in the Arctic was the sixth lowest since satellite observations began in 1979. Including 2013, all seven lowest extents on record have occurred in the past seven years. Antarctica, on the other hand, had above-average sea ice extent throughout 2013, with 116 days of new daily high extent records, including a new daily maximum sea ice area of 19.57 million km2 reached on 1 October. ENSO-neutral conditions in the eastern central Pacific Ocean and a negative Pacific decadal oscillation pattern in the North Pacific had the largest impacts on the global sea surface temperature in 2013. The North Pacific reached a historic high temperature in 2013 and on balance the globally-averaged sea surface temperature was among the 10 highest on record. Overall, the salt content in nearsurface ocean waters increased while in intermediate waters it decreased. Global mean sea level continued to rise during 2013, on pace with a trend of 3.2 mm yr-1 over the past two decades. A portion of this trend (0.5 mm yr-1) has been attributed to natural variability associated with the Pacific decadal oscillation as well as to ongoing contributions from the melting of glaciers and ice sheets and ocean warming. Global tropical cyclone frequency during 2013 was slightly above average with a total of 94 storms, although the North Atlantic Basin had its quietest hurricane season since 1994. In the Western North Pacific Basin, Super Typhoon Haiyan, the deadliest tropical cyclone of 2013, had 1-minute sustained winds estimated to be 170 kt (87.5 m s-1) on 7 November, the highest wind speed ever assigned to a tropical cyclone. High storm surge was also associated with Haiyan as it made landfall over the central Philippines, an area where sea level is currently at historic highs, increasing by 200 mm since 1970. In the atmosphere, carbon dioxide, methane, and nitrous oxide all continued to increase in 2013. As in previous years, each of these major greenhouse gases once again reached historic high concentrations. In the Arctic, carbon dioxide and methane increased at the same rate as the global increase. These increases are likely due to export from lower latitudes rather than a consequence of increases in Arctic sources, such as thawing permafrost. At Mauna Loa, Hawaii, for the first time since measurements began in 1958, the daily average mixing ratio of carbon dioxide exceeded 400 ppm on 9 May. The state of these variables, along with dozens of others, and the 2013 climate conditions of regions around the world are discussed in further detail in this 24th edition of the State of the Climate series. © 2014, American Meteorological Society. All rights reserved

Diagnostics of neoplasms of the nasal cavity and paranasal sinuses

The objective of the present work was to address earlier diagnostics of benign and malignant tumours in the nasal cavity and paranasal sinuses with a view to its improvemen. The immunohistochemical study and the analysis of its results made possible not only differential diagnostics of the tumorigenic processes in the nasal cavity and paranasal sinuses but also the estimation of the qualitative potential of each neoplasm. The immunohistochemical study demonstrated that the development of cancer of the nasal cavity and paranasal sinuses was associated with a substantial increase in the proliferative activity of epithelium and the appearance of a large amount of the mutant P53 protein in the atypical cells. The cells of inverted papilloma and unaffected epithelium exhibited only weak proliferative activity, contained cytokeratin-8 in their cytoplasm, and did not express a pathological receptor protein at the cytoplasmic membrane surface

Diagnostics of neoplasms of the nasal cavity and paranasal sinuses

The objective of the present work was to address earlier diagnostics of benign and malignant tumours in the nasal cavity and paranasal sinuses with a view to its improvemen. The immunohistochemical study and the analysis of its results made possible not only differential diagnostics of the tumorigenic processes in the nasal cavity and paranasal sinuses but also the estimation of the qualitative potential of each neoplasm. The immunohistochemical study demonstrated that the development of cancer of the nasal cavity and paranasal sinuses was associated with a substantial increase in the proliferative activity of epithelium and the appearance of a large amount of the mutant P53 protein in the atypical cells. The cells of inverted papilloma and unaffected epithelium exhibited only weak proliferative activity, contained cytokeratin-8 in their cytoplasm, and did not express a pathological receptor protein at the cytoplasmic membrane surface

Analysis of the results of a questionnaire survey among the patients presenting with nasal cavity and paranasal sinuses diseases concerning organization and quality of specialized medical assistance

The objective of the present study was to evaluate the influence of the medico-social factors on the development of nasal cavity and paranasal sinuses diseases and satisfaction of the patients with the quality of the provided specialized medical assistance. The approaches to the treatment of such patient at the pre-hospital and hospital levels are discussed.Abstract available from the publisher

Актуальные проблемы диспансеризации пациентов с заболеваниями ЛОР-органов

Protection and strengthening of population health is one of the most important elements of state social policy and the main direction in this field is the development and implementation of preventive and early detection of diseases, preventive and other medical examinations, the clinical examination.Охрана и укрепление здоровья населения - один из важнейших элементов государственной социальной политики. Основным направлением в данной сфере является реализация профилактических мероприятий по предупреждению и раннему выявлению заболеваний, а также проведение профилактических и иных медицинских осмотров, диспансеризации

The use of the Surgitron radiowave scalpel for the surgical treatment of external ear neoplasms

The objective of the present study was to elucidate etiology and clinical picture of the tumours of the external ear as well as to evaluate the effectiveness of their radiowave surgery. We sought to optimize the surgical strategy for the treatment of tumour-like masses, benign and malignant neoplasms of the external ear with the use of the Surgitron radiowave scalpel.Abstract available from the publisher

Сравнительный анализ отдаленных результатов хирургического лечения пациентов с хроническим гнойным верхнечелюстным синуситом

The article contains literary and personal data on the diagnosis of chronic maxillary sinusitis and the methods of surgical intervention in this pathology. In a comparative aspect, the results of the use of all methods of surgical intervention are shown, with further recommendations for their application in practice.В статье приведены собственные данные и данные литературы, касающиеся диагностики хронического верхнечелюстного синусита и способов хирургического лечения данной патологии. Представлены сравнительная характеристика методов хирургического вмешательства и рекомендации по их применению

The use of the Surgitron radiowave scalpel for the surgical treatment of external ear neoplasms

The objective of the present study was to elucidate etiology and clinical picture of the tumours of the external ear as well as to evaluate the effectiveness of their radiowave surgery. We sought to optimize the surgical strategy for the treatment of tumour-like masses, benign and malignant neoplasms of the external ear with the use of the Surgitron radiowave scalpel.Abstract available from the publisher

Analysis of the results of a questionnaire survey among the patients presenting with nasal cavity and paranasal sinuses diseases concerning organization and quality of specialized medical assistance

The objective of the present study was to evaluate the influence of the medico-social factors on the development of nasal cavity and paranasal sinuses diseases and satisfaction of the patients with the quality of the provided specialized medical assistance. The approaches to the treatment of such patient at the pre-hospital and hospital levels are discussed.Abstract available from the publisher