7,867 research outputs found
Statistical modelling for prediction of axis-switching in rectangular jets
Rectangular nozzles are increasingly used for modern military aircraft propulsion installations, including the roll nozzles on the F-35B vertical/short take-off and landing strike fighter. A peculiar phenomenon known as axis-switching is generally observed in such non-axisymmetric nozzle flows during which the jet spreads faster along the minor axis compared to the major axis. This might affect the under-wing stores and aircraft structure. A computational fluid dynamics study was performed to understand the effects of changing the upstream nozzle geometry on a rectangular free jet. A method is proposed, involving the formulation of an equation based upon a statistical model for a rectangular nozzle with an exit aspect ratio (ARe) of 4; the variables under consideration (for a constant nozzle pressure ratio (NPR)) being inlet aspect ratio (ARi) and length of the contraction section. The jet development was characterised using two parameters: location of the cross-over point (Xc) and the difference in the jet half-velocity widths along the major and minor axes (ÎB30). Based on the observed results, two statistical models were formulated for the prediction of axis-switching; the first model gives the location of the cross-over point, while the second model indicates the occurrence of axis-switching for the given configuration
Dry-mass sensing for microfluidics
We present an approach for interfacing an electromechanical sensor with a microfluidic device for the accurate quantification of the dry mass of analytes within microchannels. We show that depositing solutes onto the active surface of a quartz crystal microbalance by means of an on-chip microfluidic spray nozzle and subsequent solvent removal provides the basis for the real-time determination of dry solute mass. Moreover, this detection scheme does not suffer from the decrease in the sensorâs quality factor and the viscous drag present if the measurement is performed in a liquid environment, yet allows solutions to be analysed. We demonstrate the sensitivity and reliability of our approach by controlled deposition of nanogram levels of salt and protein from a micrometer-sized channel.We thank Alexander K. Buell, Igor Efimov, and Victor Ostanin for valuable discussions on QCM sensors and gratefully acknowledge financial support from the Swiss National Science Foundation (SNF), the Engineering and Physical Sciences Research Council (EPSRC), the Biotechnology and Biological Sciences Research Council (BBSRC), the European Research Council (ERC), as well as the Frances and Augustus Newman Foundation.Permission is granted to quote from an AIP publication with the customary acknowledgment of the source. Republication of an article or portions thereof (e.g., excerpts of greater than 400 words, figures, tables, etc.) in original form or in translation, as well as other types of reuse (such as use in course packs or electronic reserves) require formal permission from AIP and may be subject to fees. Although it is not a legal requirement for permission, as a courtesy, an author of the original article should be informed of any request for republication/reuse
The Sources of b-Quarks at the Tevatron and their Correlations
The leading-log order QCD hard scattering Monte-Carlo models of HERWIG,
ISAJET, and PYTHIA are used to study the sources of b-quarks at the Tevatron.
The reactions responsible for producing b and bbar quarks are separated into
three categories; flavor creation, flavor excitation, and
parton-shower/fragmentation. Flavor creation corresponds to the production of a
b-bbar pair by gluon fusion or by annihilation of light quarks, while flavor
excitation corresponds to a b or bbar quark being knocked out of the
initial-state by a gluon or a light quark or antiquark. The third source occurs
when a b-bbar pair is produced within a parton shower or during the
fragmentation process of a gluon or a light quark or antiquark (includes gluon
splitting). The QCD Monte-Carlo models indicate that all three sources of
b-quarks are important at the Tevatron and when combined they qualitatively
describe the inclusive cross-section data. Correlations between the b and bbar
quark are very different for the three sources and can be used to isolate the
individual contributions.Comment: RevTex4, 14 pages, 20 figures, submitted to Phys. Rev.
Search For Post-Merger Gravitational Waves From The Remnant Of The Binary Neutron Star Merger Gw170817
First Narrow-Band Search For Continuous Gravitational Waves From Known Pulsars In Advanced Detector Data
In Advanced LIGO, detection and astrophysical source parameter estimation of the binary black hole merger GW150914 requires a calibrated estimate of the gravitational-wave strain sensed by the detectors. Producing an estimate from each detector\u27s differential arm length control loop readout signals requires applying time domain filters, which are designed from a frequency domain model of the detector\u27s gravitational-wave response. The gravitational-wave response model is determined by the detector\u27s opto-mechanical response and the properties of its feedback control system. The measurements used to validate the model and characterize its uncertainty are derived primarily from a dedicated photon radiation pressure actuator, with cross-checks provided by optical and radio frequency references. We describe how the gravitational-wave readout signal is calibrated into equivalent gravitational-wave-induced strain and how the statistical uncertainties and systematic errors are assessed. Detector data collected over 38 calendar days, from September 12 to October 20, 2015, contain the event GW150914 and approximately 16 of coincident data used to estimate the event false alarm probability. The calibration uncertainty is less than 10% in magnitude and 10 degrees in phase across the relevant frequency band 20 Hz to 1 kHz
Preclinical detection of PrP\u3csup\u3eSc\u3c/sup\u3e in nictitating membrane lymphoid tissue of sheep
SHEEP scrapie is the prototype of a heterogeneous group of transmissible spongiform encephalopathies (TSES) which occur in humans, cattle, cats, mink and cervids. TSEs are characterised by the deposition of prion proteins (Prp-Scrapie or PrpSc) in the central nervous system of affected individuals (Prusiner 1982). PrPSc and infectivity have also been detected in the lymphoreticular system of sheep well before symptoms occur (Hadlow and others 1982, Race and others 1992). Detection of PrpSc in lymphoid tissue, such as tonsils or peripheral lymph nodes, has been proposed as a preclinical diagnostic test for scrapie (Ikegami and others 1991, Schreuder and others 1996). This short communication reports the use of a non-invasive diagnostic assay based on biopsy of lymphoid nodules in the nictitating membrane of sheep. The nictitating membrane or third eyelid (palpebra tertia) of ruminant animals consists of a cartilaginous sheet with superficial lymphoid follicles and a seromucinous secretory gland beneath the conjunctiva of the bulbar surface (Slatter and Mills 1981). The lymphoid nodules are easily biopsied under local anaesthesia. Sheep were pretreated by topical administration of proparacaine hydrochloride (Ophthetic; Allergan) and the nictitating membrane was everted with disposable 1 x 2-toothed, 5œ-inch forceps (Sklar 78055-1). Typically two clusters of lymphoid tissue were visualised above the more pale glandular tissue. A biopsy of one cluster of lymphoid tissue was collected using disposable Metzenbaum scissors (Sklar 30455) and a second set of forceps. Biopsied tissue was fixed in formalin and paraffin embedded using conventional methods. Sections typically contained four to seven lymphoid follicles
A New Technique for Finding Needles in Haystacks: A Geometric Approach to Distinguishing Between a New Source and Random Fluctuations
We propose a new test statistic based on a score process for determining the
statistical significance of a putative signal that may be a small perturbation
to a noisy experimental background. We derive the reference distribution for
this score test statistic; it has an elegant geometrical interpretation as well
as broad applicability. We illustrate the technique in the context of a model
problem from high-energy particle physics. Monte Carlo experimental results
confirm that the score test results in a significantly improved rate of signal
detection.Comment: 5 pages, 4 figure
Effects of upstream nozzle geometry on rectangular free jets
This study is aimed at understanding the effects of changing the upstream nozzle geometry on the development of rectangular free jets. An existing converging rectangular nozzle with an exit aspect ratio of 4 and a circular inlet (AR4 nozzle) has been used as the basic configuration for this work. The study is primarily based on the results of numerical simulations wherein the internal geometry variation is accomplished by changing the inlet aspect ratio (AR,) and the length of the converging section, expressed as a ratio with respect to the length of the nozzle (called 'converging section ratio*, CSR); all the other parameters are kept constant. The results from LDA experiments done on the AR4 nozzle are presented and used as validation data for the CPD simulations. Analyses of the numerical results help in understanding the variation of the jet spreading for different combinations of AR, and CSR. Two parameters are identified for describing the jet development: the cross-over point (XC), defined as the location downstream of the exit where the jet half-velocity-widths (B) along the major and minor axes are equal, and the difference in the half-velocity-widths at 30 nozzle equivalent diameters (Dm) from the exit (AB30), to ascertain the occurrence of axis-switching. For a given AR, XC varies linearly with CSR; the variation of XC is non-linear with AR, for a constant CSR. The A1330 variation is non-linear with both AR, and CSR; the other variable being kept constant. The data obtained from the simulations are further used to propose two parametric models which can be used to predict the occurrence of axis-switching, within the scope of this work. The parametric models are validated and future work is proposed.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
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