16 research outputs found

    M-ATOLL: A Framework for the Lexicalization of Ontologies in Multiple Languages

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    Walter S, Unger C, Cimiano P. M-ATOLL: A Framework for the Lexicalization of Ontologies in Multiple Languages. In: Mika P, Tudorache T, Bernstein A, et al., eds. The Semantic Web – ISWC 2014. Lecture Notes in Computer Science. Vol 8796. Cham: Springer International Publishing; 2014: 472-486.Many tasks in which a system needs to mediate between natural language expressions and elements of a vocabulary in an ontology or dataset require knowledge about how the elements of the vocabulary (i.e. classes, properties, and individuals) are expressed in natural language. In a multilingual setting, such knowledge is needed for each of the supported languages. In this paper we present M-ATOLL, a framework for automatically inducing ontology lexica in multiple languages on the basis of a multilingual corpus. The framework exploits a set of language-specific dependency patterns which are formalized as SPARQL queries and run over a parsed corpus. We have instantiated the system for two languages: German and English. We evaluate it in terms of precision, recall and F-measure for English and German by comparing an automatically induced lexicon to manually constructed ontology lexica for DBpedia. In particular, we investigate the contribution of each single dependency pattern and perform an analysis of the impact of different parameters

    On the Mental Workload Assessment of Uplift Mapping Representations in Linked Data

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    Self-reporting procedures have been largely employed in literature to measure the mental workload experienced by users when executing a specific task. This research proposes the adoption of these mental workload assessment techniques to the task of creating uplift mappings in Linked Data. A user study has been performed to compare the mental workload of “manually” creating such mappings, using a formal mapping language and a text editor, to the use of a visual representation, based on the block metaphor, that generate these mappings. Two subjective mental workload instruments, namely the NASA Task Load Index and the Workload Profile, were applied in this study. Preliminary results show the reliability of these instruments in measuring the perceived mental workload for the task of creating uplift mappings. Results also indicate that participants using the visual representation achieved smaller and more consistent scores of mental workload

    An Investigation Of Essential Elements Of The Reading Process By Means Ofstandard And Experimental Administrations Of The Rorschach Inkblot Test.

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    PhDEducational psychologyUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/185492/2/6203248.pd

    The lonely teacher /

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    Comprend des bibliogr.Index: p. 151-15

    Digital library information-technology infrastructures

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    Περιέχει το πλήρες κείμενοThis paper charts a research agenda on systems-oriented issues in digital libraries. It focuses on the most central and generic system issues, including system architecture, user-level functionality, and the overall operational environment. With respect to user-level functionality, in particular, it abstracts the overall information lifecycle in digital libraries to five major stages and identifies key research problems that require solution in each stage. Finally, it recommends an explicit set of activities that would help achieve the research goals outlined and identifies several dimensions along which progress of the digital library field can be evaluated

    Research Challenges and Opportunities in Knowledge Representation

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    Modern intelligent systems in every area of science rely critically on knowledge representation and reasoning (KR). The techniques and methods developed by the researchers in knowledge representation and reasoning are key drivers of innovation in computer science; they have led to significant advances in practical applications in a wide range of areas from natural-­‐language processing to robotics to software engineering. Emerging fields such as the semantic web, computational biology, social computing, and many others rely on and contribute to advances in knowledge representation. As the era of “Big Data” evolves, scientists in a broad range of disciplines are increasingly relying on knowledge representation to analyze, aggregate, and process the vast amounts of data and knowledge that today’s computational methods generate. We convened the Workshop on Research Challenges and Opportunities of Knowledge Representation in order to take stock in the past decade of KR research, to analyze where the major challenges are, to identify new opportunities where novel KR research can have major impact, and to determine how we can improve KR education as part of the core Computer Science curriculum. The main outcome of the workshop is a set of recommendations both for KR research and for policy-­‐ makers to enable major advancements that will have broad impact in science, technology, and education

    Human cytokines activate JAK-STAT signaling pathway in porcine ocular tissue

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    BACKGROUND: The JAK/STAT (Janus Tyrosine Kinase, Signal Transducers and Activators of Transcription) pathway is associated with cytokine or growth factor receptors and it is critical for growth control, developmental regulation and homeostasis. The use of porcine ocular cells as putative xenotransplants appears theoretically possible. The aim of this study was to investigate the response of various porcine ocular cells in vitro to human cytokines in regard to the activation of JAK-STAT signaling pathways. METHODS: Porcine lens epithelial cells, pigmented iris epithelial cells and pigmented ciliary body cells were used in this study. These cells were isolated from freshly enucleated porcine eyes by enzymatic digestion. Cultured cells between passages 3-8 were used in all experiments. Electromobility shift assay (EMSA), proliferation assay, immunofluorescence staining and flow cytometry were used to evaluate the JAK-STAT signaling pathway in these cells. RESULTS: JAK/STAT signaling pathways could be activated in porcine pigmented epithelial ciliary body cells, in pigmented iris epithelial cells and in lens epithelial cells in response to porcine and human interferons and cytokines. All cells showed very strong STAT1 activation upon stimulation with porcine interferon-gamma. Porcine ocular cells also respond to human cytokines; IFN-alpha induced strong activation of STAT1 in EMSA, flow cytometry and immunofluorescence experiments whereas activation of STAT3 was less strong in EMSA, but strong in flow cytometry and immunofluorescence. Human recombinant IL-6 activated STAT3 and human IL-4 activated STAT6. With the help of immunofluorescence assay and flow cytometry we observed nuclear localization of STAT proteins after activation of porcine ocular cells with cytokines and interferons. Human IFN-alpha had an inhibitory effect on porcine ocular cells in proliferation assays. CONCLUSION: Our study demonstrated that some types of human cytokines and interferon activa intracellular JAK-STAT signaling pathways in porcine ocular cells. We hypothesize that direct stimulation of the JAK-STAT pathway in porcine cells in response to human cytokines will lead to complications or failure, if pig-to-human ocular tissue xenotransplantation were to be carried out. For successful xenotransplantation among other obstacles there must be new approaches developed to regulate signaling pathways
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