8 research outputs found
Improvisation in a Fourth-Grade Music Class
- Publication venue
- Scholar Commons
- Publication date
- 01/01/2014
- Field of study
With the intent of improving the understanding of music learning, I investigated the processes of tonal, rhythm, melodic, and harmonic improvisation among my fourth-grade students and me. The following were the guiding research questions. 1. How did I adapt music improvisation strategies for my intact class of fourth-grade students? 2. How did those students participate in music improvisation experiences? 3. How did those students describe their music improvisation experiences? Seventeen fourth-grade students participated in this study, and I participated in this study as a participant observer. Over the course of five weeks, I taught ten 50-minute music classes, where I engaged students in a variety of improvisation activities. Data sources comprised video-recordings, student journals, my written reflections and observations, learning plans, and audio-recordings. I transcribed, coded, and analyzed the data for emergent themes. Those themes included (a) establishing an effective music-learning environment, (b) strategy adaptations to scaffold music skills, and (c) students\u27 shared positive experiences. Additionally, I provided descriptions of individual, improvisation-learning experiences via vignettes. The improvisation teaching and learning process is a multifaceted phenomenon containing complicated emotional, social, and musical elements that still need further investigation; however, my experiences with these fourth-grade students has led me to believe that through improvisation, music educators may be able to foster creativity and self-expression while simultaneously developing students\u27 music skills and confidence levels
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- Author
- Abbass Hakam
- Adhikari Neill
- Affleck Julia
- Agno Sathianathan Ronan
- Ahmad Norfaizan
- Ahmed Iram
- Ainscough Kate
- Al Qasim Eman
- Al Swaidan Lolowa
- Al-Bassam Wisam
- Al-Beidh Farah
- Al-Beidh Farah
- Albert Martin
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Allan Angela
- Allan Elizabeth
- Allen Louise
- Allibone Suzanne
- Amaro dos Santos Catorze Teodoro
- Anderson Tom
- Andric Zdravko
- Angus Derek
- Angus Derek C
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Annane Djillali
- Anstey Matthew
- Antcliffe David
- Aparicio Christelle
- Appelt Peter
- Arabi Yaseen
- Arabi Yaseen
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arishi Hatim
- Arnold Donald
- Asghar Adeeba
- Ashelford Angela
- Attwood Ben
- Austin Karen
- Aysel Florescu Simin
- Azaiz Amine
- Babel Jakša
- Babio-Galan Maite
- Badie Julio
- Bagshaw Sean
- Baillie Kenneth
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
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- Banach Dorota
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- Barbazza Leanne
- Barber Russell
- Barge Deborah
- Barnes Nicky
- Baršić Bruno
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- Basile Kim
- Bass Frances
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- Bauchmuller Kris
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- Beane Abigail
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- Benzekri Dalila
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- Bhimani Zahra
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- Bihari Shilesh
- Binnie Alexandra
- Bion Julian
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- Birch Janine
- Birch Jenny
- Birchall Katie
- Birkinshaw Isobel
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- Bloos Frank
- Board Jasmin
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- Bonten Marc
- Bonten Marc
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- Shaw Joanne
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- Sheffield Jonathan
- Shehabi Yahya
- Shovelton Charmaine
- Shrestha Tapaswi
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- Silversides Jon
- Sim Malcolm
- Simmonds Catherine
- Simons Koen
- Simpson Joanne
- Simpson Scott
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- Sinha Pratik
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- Small Charlotte
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- Smee Joanna
- Smith Joanne
- Smith John
- Smith Judith
- Smith Julie
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- Smith Roger
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- Smith Tim
- Smuts Sara
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- Thomas Amy
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- Thomson Nicola
- Thrush Jessica
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- Uyeki Tim
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- van Bentum Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van de Veerdonk Frank
- van de Veerdonk Frank
- Van Der Heyden Kym
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- van’t Hoff Willian
- Vates Jennifer
- Vautier Sarah
- Vazquez-Grande Gloria
- Venkatesh Bala
- Venkatesh Balasubramanian
- Venz Ellen
- Verlander Mark
- Verrier Nathalie
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- Voicu Sebastian
- Vowell Emma
- Vujaklija Brajković Ana
- Vuylsteke Alain
- Wagh Atul
- Walden Andrew
- Walker Rachel
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- Walsh Tim
- Walsham James
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- Warnock Majella
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Waugh Victoria
- Webb Steve
- Webb Steven A
- Wedd Steve
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- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Wetherill Bill
- Whelan Ruth
- Whileman Amanda
- Whitbread Jennifer
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Wibrow Bradley
- Wigbers J
- Wilby Elizabeth
- Wild Laura
- Wild Laura
- Wilding Laura
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- Wilkinson Dean
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- Williams Alexandra
- Williams Erin
- Williams Hannah
- Williams Karen
- Williams Patricia
- Williams Patricia
- Williams Penny
- Williams Tony
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- Williamson Dawn
- Williamson James
- Wilson Karen
- Wilson Maggie
- Wiseman Sophie
- Wong Helen
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Writing Committee for the REMAP-CAP Investigators
- Xavier Kugan
- Xia Le Tai Charlotte
- Yarad Elizabeth
- Yates David
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Yusuff Hakeem
- Zaharia Miahela Florentina
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zarychanski Ryan
- Zhao Xiao Bei
- Zinzoni Vanessa
- Zitter Letizia
- Đimoti Renata
- Publication venue
- JAMA: Journal of the American Medical Association
- Publication date
- 06/10/2020
- Field of study
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707
Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19
- Author
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Aguilar-Dano April
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Amri Ali
- Al Enezi Farhan
- Al Qasim Eman
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderink Bashar
- Alderman Meera
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Farisha
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Alqahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Amatya Sameena
- Ambrosino Richard
- Anders Jeanette
- Anderson Thomas
- Andreae Mark
- Andric Zdravko
- Angus Derek
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Apte Yogesh
- Arabi Yaseen
- Arachchige Malka
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Aryal Diptesh
- Asif Namra
- Aspinwall Angelique
- Attanayaka Udara
- Attokaran Antony
- Attwood Ben
- Au Carly
- Austin Karen
- Austin Pauline
- Avard Bronwyn
- Awan Sidra
- Azaiz Amine
- Azergui Nora
- Azzaui Harun
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- Babu Suresh
- Bacon Gina
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- Badie Julio
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- Baillie Kenneth
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- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
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- Bamford Peter
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- Barbash Ian
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- Bariola Ryan
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- Raczek James
- Rad Laura
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- Rai Sabi
- Raithatha Ajay
- Raj Ashok
- Ramakrishnan N
- Ramali Mohamed
- Ramos Angelo
- Ramos Lidia
- Randell Georgina
- Rangan Ritika
- Ranganathan Lakshmi
- Rao Deepak
- Rashan Sumayyah
- Ratnam Valli
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- Rennit Pille
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- Ricketts Daniel
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- Rodríguez-Gómez Jorge
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- Rostron Anthony
- Roth Jason
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- Roy Alistair
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- Rueß-Paterno Giusi
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- Sanderson Amanda
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- Siami Shidasp
- Sibin Sindhu
- Sicat Christine
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- Siddiqui Ayesha
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- Smith Emma
- Smith John
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- Smith Matthew
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- Smith Roger
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- Smyth Michelle
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- Spencer Stephen
- Spencer Thomas
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- Stephanie Gelinotte
- Sterba Martin
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- Stronach Lucy
- Subbanna Umesh
- Suber Tomeka
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- Sundaram Radha
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- Sutton Joanne
- Svitškar Nikolai
- Swabe Jacqueline
- Sweet Katie
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- Thomas Vicky
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- Thompson Taylor
- Thomson Nicola
- Thrush Jessica
- Thurairatnam Saranya
- Tierney Carey
- Tinmouth Alan
- Tlayjeh Haytham
- Toffalo Sue
- Tolppa Timo
- Tomlinson Helen
- Tong Steve
- Tong Steven
- Tony Kiran
- Totzke Juliane
- Touma Omar
- Towns Miriam
- Trapani Tony
- Trask Kara
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- Tridente Ascanio
- Trim Fiona
- Trimmer Ken
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- Troeman Darren
- Trues Estefania
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- Tsang Jennifer
- Tsinaslanidis Georgios
- Tuckwell Caroline
- Tully Redmond
- Tully Riona
- Tung Raymond
- Turgeon Alexis
- Turki Salah
- Turner Anne
- Turner Keri
- Turner-Bone Ian
- Turns Margaret
- Tv Bharath
- Udayanga Ishara
- Uddin Ruzena
- Udy Andrew
- Umrani Zulfiqar
- Uriel Alison
- Ustianowski Andrew
- Uyeki Tim
- Vaara Suvi
- Vaduganathan Muthiah
- Vahtera Annukka
- Vale Cassandra
- Valentine Eliza
- Vamplew Luke
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van Bree Sjoerd
- van de Veerdonk Frank
- van den Berg Lettie
- van den Oever Huub
- van der Eng Hetty
- van der Heyden Kymbalee
- van der Kraan-Donker Annemarie
- van Gulik Laura
- van Kimmenade Roland
- van Nieuwkoop Kees
- van Oosten Nienke
- van Opdorp Marjolein
- van Vonderen Marit
- van Zanten Arthur
- van Zuylen Tamara
- Vanjak Christian
- Vanmali Piyush
- Vargas Jr. Jesus
- Varghese Siby
- Vautier Sarah
- Vazquez-Grande Gloria
- Veenith Tonny
- Venkatesh Bala
- Venz Ellen
- Verlander Mark
- Vermassen Joris
- Vermeiren Daisy
- Verrier Nathalie
- Vertue Mark
- Verula Jerik
- Victor Saji
- Viehman Alex
- Vieillard-Baron Antoine
- Vignesh C
- Vincent Rachel
- Virdee Satwinder
- Visser Yorik
- Vita Tina
- Vodovar Dominique
- Voicu Sebastian
- Voigt Ingo
- Voiriot Guillaume
- Voza Antonio
- Vrolijk Loes
- Vuylsteke Alain
- Wagh Atul
- Wahl Nadine
- Waite Alicia
- Walden Andrew
- Walker Gena
- Walker Rachel
- Walsh Joanne
- Walsh Tim
- Walsham James
- Wang Shu
- Ward Geraldine
- Ward Kathryn
- Ward Luke
- Warnapura Loku
- Warnock Majella
- Watchorn Olivia
- Waters Abby
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watts Angela
- Waugh Victoria
- Webb Steve
- Weber Lisa
- Weerasinghe Thanuja
- Weismann Dirk
- Weiss Daniel
- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Westlake Samantha
- Wetherill Bill
- Wetzold Richard
- Whileman Amanda
- Whitbread Jennifer
- White Alison
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Whitehouse Tony
- Wibrow Bradley
- Wigbers Jeanette
- Wilby Elizabeth
- Wilcox Elizabeth
- Wilcox Louise
- Wild Helen
- Wild Laura
- Wilding Laura
- Wiles Matt
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Angharad
- Williams Anna
- Williams Erin
- Williams Gemma
- Williams Karen
- Williams Patricia
- Williams Tony
- Williams Virginie
- Willis Joanna
- Willson Jayne
- Wilson Anna
- Wilson Craig
- Wilson Maggie
- Winters James
- Winters Lauren
- Wise Matt
- Wiseman Sophie
- Wisniewski Mary
- Wittenberg Wendy
- Wnuk Chris
- Woelke Amy
- Wong Helen
- Wong Onyee
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Wright Chris
- Wunderley Renee
- Wyatt Rachel
- Wylie Katharine
- Xavier Kugan
- Yang Yang
- Yarad Elizabeth
- Yates David
- Yealy Donald
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Đimoti Renata
- Publication venue
- American Medical Association
- Publication date
- 05/04/2022
- Field of study
International audienc
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- Adriano Enrico
- Adrião Diana
- Ageel Saleh Al
- Ahmed Shakeel
- Aiello Marina
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Adam
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Anwar Kazi Rubayet
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asaki Motohiro
- Asensio Angel
- Ashley Elizabeth A.
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atique Anika
- Attanyake AM Udara Lakshan
- Auchabie Johann
- Auger Christelle Chantalat
- Aumaitre Hugues
- Auvet Adrien
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J. Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Berge Marcel van den
- Bergeaud Delphine
- Bergin Hazel
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Betz Adam
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Bihan Clément Le
- Bisoffi Zeno
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Bonelli Patrizia
- Bonfasius Aurelius
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Bounphiengsy Thipsavanh
- Bountthasavong Latsaniphone
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O
- Bris Cyril Le
- Browne Alex
- Browne Shaunagh
- Brozzi Nicolas
- Brusse-Keizer Marjolein
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Buonsenso Danilo
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O
- Callahan Mia
- Calligy Kate
- Calvache Jose Andres
- Caminiti Caterina
- Camões João
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlacci Francesca
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Carvalho Leonor
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavayas Alexandros
- Cárcel Sheila
- Ceccato Adrian
- Cely Lina Morales
- Cerkovnik Shelby
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chaleunphon Bounthavy
- Chan Adrienne
- Chand Meera
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Chatterjee Allegra
- Chau Nguyen Van Vinh
- Chen Anjellica
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chetta Alfredo Antonio
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chirouze Catherine
- Chiumello Davide
- Cho Hwa Jin
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chommanam Danoy
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chow Yock Ping
- Christy Nathaniel
- Chua Hiu Jian
- Chua Jonathan
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Clifton Lei
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connor Marie
- Conrad Anne
- Contreras Sofía
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
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- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A
- Dantas Jorge
- Darshana B. P. Sanka Ruwan Sri
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de Jong Menno
- de Loughry Gillian
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- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M
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- Klenerman Paul
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- Knight Stephen R
- Kobbe Robin
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- Lopez-Revilla Jose W.
- Lordemann Anja Grosse
- Loschner Anthony L.
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- Maillet Mylène
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- Mercier Emmanuelle
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- null null
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- Ong David S. Y.
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- Payen Jean-François
- Peake Sandra L
- Peariasamy Kalaiarasu
- Peariasamy Kalaiarasu M.
- Peek Giles J.
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- Postma Douwe F.
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- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G.
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- Taib Shahdattul Mawarni
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- Tawfik Hassan
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- Thomson Emma C.
- Thurai Surain Raaj Thanga
- Thuy Duong Bich
- Thwaites Ryan S.
- Ticinesi Andrea
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S
- Timsit Jean-François
- Tissot Noémie
- Toh Jordan Zhien Yang
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- Trioux Théo
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- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turgeon Alexis F.
- Turmel Jean-Marie
- Turnier Paul Le
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Twillert Gitte Van
- Uchiyama Makoto
- Udayanga PG Ishara
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valentini Piero
- Valk Paul van der
- Valran Amélie
- Valzano Ilaria
- van Someren Greve Frank
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasconcelos Malte Kohns
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veen Ilonka van
- Veeran Shaminee
- Veislinger Aurélie
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- Villoldo Andrea
- Vishwanathan Gayatri
- Visseaux Benoit
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- Vongsouvath Manivanh
- Vonkeman Harald
- Voort Peter Van der
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Werf Sylvie Van Der
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Patricia J
- Williams Virginie
- Willigen Hugo Van
- Wils Evert-Jan
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Xin Ci
- Wong Yew Sing
- Wright Natalie
- Xian Gan Ee
- Xian Lim Saio
- Xuan Kuan Pei
- Xynogalas Ioannis
- Yacoub Sophie
- Yakop Siti Rohani Binti Mohd
- Yamazaki Masaki
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yiaye Touxiong
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zabert Gustavo E
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zaidan Nor Zaila Binti
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zawadka Konrad
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Publication date
- 16/07/2024
- Field of study
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) in COVID-19 patients as one of the most severe preventable complications of COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right at admission. Using a dataset of more than 800,000 COVID-19 patients from an international cohort, we propose a cost-sensitive gradient-boosted machine learning model that predicts occurrence of PE and death at admission. Logistic regression, Cox proportional hazards models, and Shapley values were used to identify key predictors for PE and death. Our prediction model had a test AUROC of 75.9% and 74.2%, and sensitivities of 67.5% and 72.7% for PE and all-cause mortality respectively on a highly diverse and held-out test set. The PE prediction model was also evaluated on patients in UK and Spain separately with test results of 74.5% AUROC, 63.5% sensitivity and 78.9% AUROC, 95.7% sensitivity. Age, sex, region of admission, comorbidities (chronic cardiac and pulmonary disease, dementia, diabetes, hypertension, cancer, obesity, smoking), and symptoms (any, confusion, chest pain, fatigue, headache, fever, muscle or joint pain, shortness of breath) were the most important clinical predictors at admission. Age, overall presence of symptoms, shortness of breath, and hypertension were found to be key predictors for PE using our extreme gradient boosted model. This analysis based on the, until now, largest global dataset for this set of problems can inform hospital prioritisation policy and guide long term clinical research and decision-making for COVID-19 patients globally. Our machine learning model developed from an international cohort can serve to better regulate hospital risk prioritisation of at-risk patients
The value of open-source clinical science in pandemic response: lessons from ISARIC
- Author
- Aasiyah Rashan
- Aasmine Kaur
- Abdulrahman Al-Fares
- Abhijit Duggal
- Adam Betz
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agamemnon Bakakos
- Agn??s Meybeck
- Agn??s Sommet
- Agnieszka Oldakowska
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Cucino
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Martinelli
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J. Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Abbas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Ali Rehan
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M. Meynert
- Alistair Nichol
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- AM Udara Lakshan Attanyake
- Am??lie Valran
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Lester-Grant
- Amy Stone
- Ana Aroca
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Luiza Valle
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Tveita
- Andr?? Cabie
- Andr?? Dias
- Andr?? Roberto
- Andr??s Orquera
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Dagens
- Andrew Hershey
- Andrew Udy
- Andrey A Svistunov
- Andriy Bal
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-H??l??ne Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B. Docherty
- Annmarie O'Callaghan
- Ansley Hamer
- Ant??nio Mesquita
- Anthony Gordon
- Anthony L. Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ho
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Ars??ne Kpangon
- Arsalan Rahutullah
- Arshad Taqi
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asami Ito
- Asfia Sultana
- Asgar Rishu
- Ashok Kumar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Aur??lie Papadopoulos
- Aur??lie Veislinger
- Aur??lie Wiedemann
- Aurelius Bonfasius
- Aurore Bousquet
- Axelle Braconnier
- Azlan Mat Soom
- Azrina Ralib
- B. P. Sanka Ruwan Sri Darshana
- B??n??dicte Lefebvre
- B??n??dicte Rossignol
- Bailey Cassandra
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barbara Wanjiru Citarella
- Basanta Gauli
- Basri Mat Nor
- Beatrice Alex
- Beatriz Amorim Beltr??o
- Ben Morton
- Benedict Sim Lim Heng
- Benigno Ferreira
- Benjamin Bach
- Benjamin Lefevre
- Benjamin Smood
- Benjamine Sarton
- Beno??t Roze
- Beno??t Thill
- Benoit Visseaux
- Bernard Cholley
- Bernardo Neves
- Bernhard Roessler
- Bertrand Dussol
- Bharath Kumar Tirupakuzhi Vijayaraghavan
- Bianca Boxma
- Bianca DeBenedictis
- Biing Horng Lee
- Bipin Karki
- Birgitte Stiksrud
- Blake Mergler
- Blandine Rammaert
- Bouchra Loufti
- Brenda Molloy
- Brenda Reeve
- Brian Marsh
- Brigid Flynn
- Brigitte Elharrar
- Briseida Parra
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bruno Sarmento Banheiro
- Bryan Whelan
- Budha Charan Singh
- C??cile Goujard
- C??cile Mear-Passard
- C??cile Tromeur
- C??cile Yelnik
- C??dric Joseph
- C??dric Laou??nan
- C??line Dorival
- C??line Ficko
- C??line Michelanglei
- C??sar Vieira
- Caitriona Cody
- Calvin Wong
- Cameron J. Fairfield
- Camile Bouisse
- Camille Couffignal
- Caren Friedrich
- Carine Roy
- Carla Eira
- Carlo Giaquinto
- Carlos Alexandre Antunes de Brito
- Carlos Lumbreras Bermejo
- Carlos M. Luna
- Carlos Pimentel
- Carmen Infante Dominguez
- Carola Pierobon
- Carolien van Netten
- Caroline Cullen
- Caroline Kosgei
- Caroline Martins Rego
- Caroline Mudara
- Caroline Semaille
- Carolline Araujo
- Carrol Gamble
- Cassidy Codan
- Cassie Lawrence
- Catarina Pires
- Catarina Silva
- Catherine A. Shaw
- Catherine Blier
- Catherine Chakveatze
- Catherine Chirouze
- Catherine L. Hough
- Catherine Marquis
- Catherine Motherway
- Cecile Azoulay
- Cecilia Canepa
- Ceila Maria Sant`Ana Malaque
- Celina Turchi Martelli
- Chamira Kodippily
- Chan Chee Eng
- Chantre Lima
- Charbel Maroun Eid
- Charlene Da Silveira
- Charles Crepy D'Orleans
- Charline Vauchy
- Charlotte Salmon Gandonniere
- Charlotte Summers
- Cheryl Bartone
- Chian Hui Yeoh
- Chiara Robba
- Chiara Simona Cardellino
- Chiara Vitiello
- Chih-Hsien Wang
- Chloe Carpenter
- Chloe Donohue
- Chris Kandel
- Chris McKay
- Christel Arnold-Day
- Christelle Chantalat Auger
- Christelle Delmas
- Christelle Paul
- Christelle Tual
- Christian Buesaquillo
- Christian Prebensen
- Christian Rabaud
- Christiana Kartsonaki
- Christl A. Donnelly
- Christophe Fraser
- Christophe Rapp
- Christopher A. Green
- Christy Kay
- Ciara Doran
- Cl??ment Le Bihan
- Claire Andrejak
- Claire Foley
- Claire Kelly
- Claire Levy-Marchal
- Claire Roger
- Clara Flateau
- Clara Mouton Perrot
- Clare Jackson
- Clarice Tanaka
- Clark D. Russell
- Clark Owyang
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudia Milena Orozco-Chamorro
- Claudia Montes
- Claudia Sepulveda
- Claudina Cruz
- Claudine Badr
- Claudio Duarte Fonseca
- Cleide Barrigoto
- Clotilde Allavena
- Coilin Smyth
- Colin McArthur
- Colin McCloskey
- Coline Jaud-Fischer
- Colleen Curran
- Conar O'Neil
- Coralie Khan
- Coralie Tardivon
- Corine Delsing
- Corinne Daniel
- Cornelius Rau
- Courtney Greene
- Cristinava Vajdovics
- Cynthia Alegre
- Cynthia Braga
- Cyril Cadoz
- Cyril Le Bris
- Dafsah Juzar
- Dag Henrik Reikvam
- Daisuke Kasugai
- Dalia Lopez-Colon
- Damien Bouhour
- Damien Traynor
- Dan Meyer
- Daniel Glikman
- Daniel Haber
- Daniel Herr
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- Daniel Marino
- Daniel Mathieu
- Daniel Munblit
- Daniel Perez
- Daniel Plotkin
- Daniela Guerreiro
- Danielle Jaafar
- Darakhshan Kanwal
- Darren Dahly
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- David Maslove
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- Dawn Higgins
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- Decy Subekti
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- Deepali Kumar
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- Denise Foster
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- Desy Rusmawatiningtyas
- Detlef Kindgen-Milles
- Devachandran Jayakumar
- Devika Dixit
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- Diana Adri??o
- Diana P??voas
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- Diane Ponscarme
- Didier Laureillard
- Diego Bastos
- Diego de Mendoza
- Diego Fernando Bautista Rincon
- Diego Franch-Llasat
- Diego Rolando Morocho Tutillo
- Dimitra Melia Myrodia
- Dinesh Kuriakose
- Diogo Borges
- Diogo Lopes
- Diptesh Aryal
- Djura Piersma
- Domenico Luca Grieco
- Dominic So
- Dominique Deplanque
- Dominique Luton
- Dori-Ann Martin
- Dorothea Rosenberger
- Dorothy Breen
- Doug Robb
- Dounia Bouhmani
- Douwe F. Postma
- Dr Marianne Fraher
- Dubravka Supic
- Duc Nguyen
- Duong Bich Thuy
- Dyah Kanyawati
- Dzawani Muhamad
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- Elaine Conway
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- Elena Molinos
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- Elisabeth Botelho-Nevers
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- Elise Artaud-Macari
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- Elsa Nyamankolly
- Else Quist-Paulsen
- Ema Leal
- Eman Al Qasim
- Emanuele Durante-Mangoni
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- Emily Neumann
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- Emma Clarke
- Emma Costigan
- Emmanuel Roilides
- Emmanuelle A Dankwa
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- Emmanuelle Mercier
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- F??lix Djossou
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- Fran??ois T??oul??
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- Guillermo Maestro de la Calle
- Guylaine Castor-Alexandre
- Gwena??l Le Moal
- Gwenha??l Colin
- Gyan Sandhu
- H M Upulee Pabasara
- H??l??ne Esperou
- H??l??ne Salvator
- Ha Sha Lene
- Haixia Shi
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- Hans Martin Bosse
- Harald Vonkeman
- Hassan Tawfik
- Hayato Taniguchi
- Hayley Hardwick
- Hazel Bergin
- Heidi Ammerlaan
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- Heidi Gruner
- Helen Doherty
- Helen Tuite
- Helen Vaughan
- Helena Barrasa
- Hem Paneru
- Heng Gee Lee
- Henk Vanoverschelde
- Henrique Mateus Fernandes
- Henry Castrill??n
- Hernando Torres-Zevallos
- Herv?? Le Nagard
- Hiba Zayyad
- Hikombo Hitoto
- Himed Musaab
- Hiroaki Hiraiwa
- Hiroaki Shimizu
- Hiroyuki Tanaka
- Hiu Jian Chua
- Hodane Yonis
- Hoi Ping Shum
- Holger Neb
- Hon Shen Png
- Hongru Ren
- Hubert Tessier-Grenier
- Huda Alfoudri
- Huda Taqdees
- Hugo In??cio
- Hugo Miranda-Maldonado
- Hugo Mouquet
- Hugues Aumaitre
- Hugues Cordel
- Hussain Tanveer
- Huynh Trung Trieu
- Hwa Jin Cho
- Iam Claire E. Sarmiento
- Ida Carroll
- Ignacio Martin-Loeches
- Ikram Houas
- Ilka Engelmann
- Ilonka van Veen
- Imran Ali
- Imrana Khalid
- In??s Carqueja
- Indrek R??tsep
- Ingrid G. Bustos
- Ioana Grigoras
- Ioannis Trontzas
- Ioannis Xynogalas
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- Isabelle Pironneau
- Issrah Jawad
- Ithan D. Peltan
- Ivo Castro
- J Kevin Baird
- J. Kenneth Baillie
- J. Perren Cobb
- J??r??me Dimet
- J??r??mie Guedj
- J??r??mie Pasquier
- Jack Song Chia
- Jacky Y. Suen
- Jacobien Ellerbroek
- Jade Ghosn
- Jae Burm Kim
- Jaganathan Selvanayagam
- Jai Madhok
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- Jaime Hernandez-Montfort
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- Jamel Ortoleva
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- James Lee
- James Scott-Brown
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- Jan Heerman
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- Janet Liang
- Janet T. Scott
- Jaques Sztajnbok
- Jarne Van Hattem
- Jason Bouziotis
- Javier Maynar
- Javier Osatnik
- Jean Baptiste Assie
- Jean Christophe Lucet
- Jean Foley
- Jean-Beno??t Arlet
- Jean-Charles Gagnard
- Jean-Charles Preiser
- Jean-Christophe Goffard
- Jean-Daniel Lelievre
- Jean-Fran??ois Payen
- Jean-Fran??ois Timsit
- Jean-Luc Diehl
- Jean-Marc Chapplain
- Jean-Marie Turmel
- Jean-S??bastien Hulot
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- Jennifer June
- Jenny Lennon
- Jeremy J. Farrar
- Jeronimo Graf
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- Jia Wei
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- Jimmy Mullaert
- Jin Yi Goh
- Jo Dalton
- Jo??o Alves
- Jo??o Cam
- Jo??o Estev??o
- Jo??o Martins
- Jo??o Melo Alves
- Jo??o Oliveira
- Jo??o Teixeira
- Joan G??mez-Junyent
- Joana Ferr??o
- Joanne Downey
- Joao Joao Mendes
- Joaqu??n Baruch
- Jodat Saleem
- Jodat Saleem
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- Johannes Gebauer
- John Bourke
- John F. Fraser
- John G. Laffey
- John Marshall
- Johnny McKeown
- Jolanta Popielska
- Jonathan Chua
- Jonathan Crump
- Jonathan Golob
- Jonathan Remppis
- Jonathan Samuel Ch??vez I??iguez
- Jordan Zhien Yang Toh
- Jordi Rello
- Jordi Riera
- Jorge Dantas
- Jorge Fernandes
- Jorge Paulos
- Jos?? Casimiro
- Jos?? Ernesto Vidal
- Jos?? Luis Bernal Sobrino
- Jos?? Miguel Cisneros Herreros
- Jose Andres Calvache
- Jose I Nunez
- Jose M. Mandei
- Jose Pedro Cidade
- Joshua Solomon
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- Justine Pages
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- K??vin Didier
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- Karisha Sivam
- Karl Erik M??ller
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- Karolina Nowicka
- Kashif Memon
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- Keibun Liu
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- Keith Wille
- Kenneth A. McLean
- Ker Hong Bee
- Kevin Katz
- Khor How Kiat
- Kim Keat Tan
- Kishore Mangal
- Kizy Sanchez de Oliveira
- Koji Hoshino
- Kok Wei Hao
- Kollengode Ramanathan
- Kong Yeow Kang
- Konrad Zawadka
- Konstantinos Kyriakoulis
- Konstantinos Syrigos
- Konstanty Szuldrzynski
- Kota Hoshino
- Krishna Bhavsar
- Kristian Tonby
- Kuan Pei Xuan
- Kusum Menon
- Kyle Gomez
- Laetitia Bodenes
- Lai Hui Pang
- Lance C. W. Turtle
- Lara Absil
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- Larissa Oliveira
- Lars Heggelund
- Lars S. Maier
- Laur??ne Azemar
- Laura Feeney
- Laura Marsh
- Laura Merson
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- Laure Goubert
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- Liadain Reid
- Liadain Reid
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- Lionel Piroth
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- Liv Hesstvedt
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- Lorenzo Grazioli
- Lorna Murphy
- Lorraine McAndrew
- Louis Gerbaud Morlaes
- Louise Sigfrid
- Lovkesh Arora
- Lu??s Bento
- Lu??s Patr??o
- Lu??s Val-Flores
- Luca Brazzi
- Lucia Moro
- Lucia Proen??a
- Lucian Durham III
- Lucie Le Fevre
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- Luis Felipe Reyes
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- Lysa Tagherset
- M Azhari Taufik
- M??lanie Roriz
- M??rio Ferraz
- Ma??der Pagadoy
- Machteld van der Feltz
- Madiha Hashmi
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- Maeve Kernan
- Maeve Ryan
- Magdalena Surovcov??
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- Maggie Mechlin
- Mahdad Noursadeghi
- Maia Rabaa
- Maire-Laure Casanova
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- Malcolm G. Semple
- Malte Kohns Vasconcelos
- Mamoru Komatsu
- Mangala Narasimhan
- Manuel Etienne
- Manuel Rosa-Calatrava
- Maqsood Meher
- Mar??lia Fernandes
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- Marcela Vieira Freire
- Marco Echeverria-Villalobos
- Marco Giani
- Mare Pejkovska
- Margarida Torres
- Margarite Grable
- Margaux Isnard
- Maria Amaral
- Maria Angelica Rivera Nu??ez
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- Maria Joao Silva
- Maria Lawrensia Tampubolon
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- Maria Ryan
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- Marl??ne Murris
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- Masaki Yamazaki
- Masliza Zahid
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- Pavan Kumar Vecham
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- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Volkan Korten
- Waasila Jassat
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xavier S??nchez Choez
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zubair Umer
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
International audienc
The value of open-source clinical science in pandemic response: lessons from ISARIC
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adachi Shingo
- Adam Elisabeth
- Adrião Diana
- Ageel Saleh Al
- Ahmed Shakeel
- Ain Quratul
- Ainscough Kate
- Aisa Tharwat
- Ait Hssain Ali
- Ait Tamlihat Younes
- Akimoto Takako
- Akmal Ernita
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alam Tanvir
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre K. vin
- Alfoudri Huda
- Ali Shah Naseem
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ammerlaan Heidi
- Ampaw Phoebe
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- Angoulvant François
- Ansart S. verine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Anwar Kazi Rubayet
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arali Rajeshwari
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Aroca Ana
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asaki Motohiro
- Asensio Angel
- Ashley Elizabeth
- Ashraf Muhammad
- Ashraf Sheharyar
- Asim Mohammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atique Anika
- Attanyake A. M. Udara Lakshan
- Auchabie Johann
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- Martins Ana
- Martins João
- Martins Nuno
- Martucci Gennaro
- Martynenko Olga
- Marwali Eva Miranda
- Marzukie Marsilla
- Masa Jimenez Juan Fernado
- Maslove David
- Mason Phillip
- Mason Sabina
- Masood Sobia
- Mat Nor Basri
- Matan Moshe
- Mateus Fernandes Henrique
- Mathew Meghena
- Mathieu Daniel
- Mattei Mathieu
- Matulevics Romans
- Maulin Laurence
- Maxwell Michael
- Maynar Javier
- Mazzoni Thierry
- Mc Sweeney Lisa
- McAndrew Lorraine
- McArthur Colin
- McCarthy Aine
- McCarthy Anne
- McCloskey Colin
- McConnochie Rachael
- McDermott Sherry
- McDonald Sarah E.
- McElroy Aine
- McElwee Samuel
- McEneany Victoria
- McEvoy Natalie
- McGeer Allison
- McKay Chris
- McKeown Johnny
- McLean Kenneth A.
- McNally Paul
- McNicholas Bairbre
- McPartlan Elaine
- Meaney Edel
- Mear-Passard C. cile
- Mechlin Maggie
- Meher Maqsood
- Mehkri Omar
- Mele Ferruccio
- Melo Luis
- Memon Kashif
- Mendes Joao Joao
- Menkiti Ogechukwu
- Menon Kusum
- Mentré France
- Mentzer Alexander J.
- Mercier Emmanuelle
- Mercier Noémie
- Merckx Antoine
- Mergeay-Fabre Mayka
- Mergler Blake
- Merson Laura
- Mesquita António
- Metwally Osama
- Meybeck Agnès
- Meyer Dan
- Meynert Alison M.
- Meysonnier Vanina
- Meziane Amina
- Mezidi Mehdi
- Michelagnoli Giuliano
- Michelanglei C. line
- Michelet Isabelle
- Mihelis Efstathia
- Mihnovit Vladislav
- Miranda-Maldonado Hugo
- Misnan Nor Arisah
- Mohamed Nik Nur Eliza
- Mohamed Tahira Jamal
- Moin Asma
- Molina David
- Molinos Elena
- Molloy Brenda
- Mone Mary
- Monteiro Agostinho
- Montes Claudia
- Montrucchio Giorgia
- Moore Sarah
- Moore Shona C.
- Morales Cely Lina
- Moro Lucia
- Morocho Tutillo Diego Rolando
- Morton Ben
- Motherway Catherine
- Motos Ana
- Mouquet Hugo
- Mouton Perrot Clara
- Moyet Julien
- Mudara Caroline
- Mufti Aisha Kalsoom
- Muh Ng Yong
- Muhamad Dzawani
- Mullaert Jimmy
- Muller Fredrik
- Munblit Daniel
- Muneeb Syed
- Munir Nadeem
- Munshi Laveena
- Murphy Aisling
- Murphy Lorna
- Murris Marlène
- Murthy Srinivas
- Musaab Himed
- Muyandy Gugapriyaa
- Myrodia Dimitra Melia
- Müller Karl Erik
- N Namra
- Nagpal Dave
- Nagrebetsky Alex
- Narasimhan Mangala
- Narayanan Nageswaran
- Nasim Khan Rashid
- Nazerali-Maitland Alasdair
- Neant Nadège
- Neb Holger
- Nekliudov Nikita A.
- Nelwan Erni
- Neto Raul
- Neumann Emily
- Neves Bernardo
- Ng Pauline Yeung
- Nghi Anthony
- Nguyen Duc
- Ni Choileain Orna
- Ni Leathlobhair Niamh
- Nichol Alistair
- Nitayavardhana Prompak
- Nonas Stephanie
- Noordin Nurul Amani Mohd
- Noret Marion
- Norharizam Nurul Faten Izzati
- Norman Lisa
- Notari Alessandra
- Noursadeghi Mahdad
- Nowicka Karolina
- Nowinski Adam
- Nseir Saad
- Nunez Jose I.
- Nurnaningsih Nurnaningsih
- Nyamankolly Elsa
- O Brien Fionnuala
- O'Callaghan Annmarie
- O'Donnell Max
- O'Halloran Sophie
- O'Hearn Katie
- O'Neil Conar
- O'Shea Linda
- O'Sullivan Miriam
- Occhipinti Giovanna
- OConnor Derbrenn
- Ogston Tawnya
- Ogura Takayuki
- Oh Tak-Hyuk
- Ohshimo Shinichiro
- Oldakowska Agnieszka
- Oliveira João
- Oliveira Larissa
- Olliaro Piero L.
- Ong David S. Y.
- Ong Jee Yan
- Oosthuyzen Wilna
- Opavsky Anne
- Openshaw Peter
- Orakzai Saijad
- Orozco-Chamorro Claudia Milena
- Orquera Andrés
- Ortoleva Jamel
- Osatnik Javier
- Othman Siti Zubaidah
- Ouamara Nadia
- Ouissa Rachida
- Owyang Clark
- Oziol Eric
- Pabasara H. M. Upulee
- Pagadoy Maïder
- Pages Justine
- Palacios Amanda
- Palacios Mario
- Palmarini Massimo
- Panarello Giovanna
- Panda Prasan Kumar
- Paneru Hem
- Pang Lai Hui
- Panigada Mauro
- Pansu Nathalie
- Papadopoulos Aurélie
- Parke Rachael
- Parker Melissa
- Parra Briseida
- Parrini Vieri
- Pasha Taha
- Pasquier J. rémie
- Pastene Bruno
- Patauner Fabian
- Patel Junaid
- Pathmanathan Mohan Dass
- Patricio Patricia
- Patrier Juliette
- Patrão Luís
- Patterson Lisa
- Pattnaik Rajyabardhan
- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William A.
- Payen Jean-François
- Peariasamy Kalaiarasu
- Pedrera Jiménez Miguel
- Peek Giles J.
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Pelosi Paolo
- Peltan Ithan D.
- Pereira Rui
- Perez Daniel
- Periel Luis
- Perpoint Thomas
- Pesenti Antonio
- Pestre Vincent
- Petrou Lenka
- Petrov-Sanchez Ventzislava
- Pettersen Frank Olav
- Peytavin Gilles
- Pharand Scott
- Piagnerelli Michael
- Picard Walter
- Picone Olivier
- Pierobon Carola
- Piersma Djura
- Pimentel Carlos
- Pinto Raquel
- Pires Catarina
- Pironneau Isabelle
- Piroth Lionel
- Pius Riinu
- Piva Simone
- Plantier Laurent
- Plotkin Daniel
- Png Hon Shen
- Poissy Julien
- Pokeerbux Ryadh
- Pokorska-Spiewak Maria
- Poli Sergio
- Pollakis Georgios
- Ponscarme Diane
- Popielska Jolanta
- Post Andra-Maris
- Postma Douwe F.
- Povoa Pedro
- Powis Jeff
- Prapa Sofia
- Preau S. bastien
- Prebensen Christian
- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G.
- Priyadarshani Gamage Dona Dilanthi
- Proença Lucia
- Pudota Sravya
- Pujo Semedi Bambang
- Pulicken Mathew
- Puntoni Matteo
- Purcell Gregory
- Puéchal Oriane
- Póvoas Diana
- Quesada Luisa
- Quinones-Cardona Vilmaris
- Quirós González V. ctor
- Quist-Paulsen Else
- Quraishi Mohammed
- Rabaa Maia
- Rabaud Christian
- Rabindrarajan Ebenezer
- Rafael Aldo
- Rafiq Marie
- Ragazzo Gabrielle
- Rahman Ahmad Kashfi Haji Ab
- Rahman Rozanah Abd
- Rahutullah Arsalan
- Rainieri Fernando
- Rajahram Giri Shan
- Rajapakse Nipunie
- Ralib Azrina
- Ramakrishnan Nagarajan
- Ramanathan Kollengode
- Ramli Ahmad Afiq
- Rammaert Blandine
- Ramos Grazielle Viana
- Rana Asim
- Rangappa Rajavardhan
- Ranjan Ritika
- Rapp Christophe
- Rashan Aasiyah
- Rashan Thalha
- Rasheed Ghulam
- Rasmin Menaldi
- Rau Cornelius
- Ravi Tharmini
- Raza Ali
- Real Andre
- Rebaudet Stanislas
- Redl Sarah
- Reeve Brenda
- Rehan Ali
- Rehman Attaur
- Reid Liadain
- Reikvam Dag Henrik
- Reis Renato
- Rello Jordi
- Remppis Jonathan
- Remy Martine
- Ren Hongru
- Renk Hanna
- Resende Liliana
- Resseguier Anne-Sophie
- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Tiago
- Ribeiro Maria Ines
- Richardson David
- Richardson Denise
- Richier Laurent
- Ridzuan Siti Nurul Atikah Ahmad
- Riera Jordi
- Rios Ana L.
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rivera Nuñez Maria Angelica
- Rizer Nicholas
- Robb Doug
- Robba Chiara
- Roberto André
- Roberts Stephanie
- Robertson David L.
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia Simão
- Rodriguez Abreu Julia
- Roessler Bernhard
- Roger Claire
- Roger Pierre-Marie
- Roilides Emmanuel
- Rojek Amanda
- Romaru Juliette
- Roncon-Albuquerque Jr Roberto
- Roriz M. lanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossetti Matteo
- Rossignol B. nédicte
- Rossignol Patrick
- Rousset Stella
- Roy Carine
- Roze Benoît
- Rusmawatiningtyas Desy
- Russell Clark D.
- Ryan Maeve
- Ryan Maria
- Ryckaert Steffi
- Rygh Holten Aleksander
- Rätsep Indrek
- Saba Isabela
- Sadaf Sairah
- Sadat Musharaf
- Sahraei Valla
- Saint-Gilles Maximilien
- Sakiyalak Pranya
- Salahuddin Nawal
- Salazar Leonardo
- Saleem Jodat
- Sales Gabriele
- Sallaberry Stéphane
- Salmon Gandonniere Charlotte
- Salvator H. lène
- Sanchez de Oliveira Kizy
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandhu Zulfiqar
- Sandrine Pierre-François
- Sandulescu Oana
- Santos Marlene
- Sarfo-Mensah Shirley
- Sarmento Banheiro Bruno
- Sarmiento Iam Claire E.
- Sarton Benjamine
- Satyapriya Sree
- Satyawati Rumaisah
- Saviciute Egle
- Savio Raymond
- Savvidou Parthena
- Saw Yen Tsen
- Schaffer Justin
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Schwartz Gary
- Scott Janet T.
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvanayagam Jaganathan
- Selvarajoo Mageswari
- Semaille Caroline
- Semple Malcolm G.
- Senian Rasidah Bt
- Senneville Eric
- Sepulveda Claudia
- Sequeira Filipa
- Sequeira T. nia
- Serpa Neto Ary
- Serrano Balazote Pablo
- Shadowitz Ellen
- Shahidan Syamin Asyraf
- Shahnaz Hasan Mohd
- Shamsah Mohammad
- Shankar Anuraj
- Sharjeel Shaikh
- Sharma Pratima
- Shaw Catherine A.
- Shaw Victoria
- Shi Haixia
- Shiban Nisreen
- Shiekh Mohiuddin
- Shiga Takuya
- Shime Nobuaki
- Shimizu Hiroaki
- Shimizu Keiki
- Shimizu Naoki
- Shindo Nahoko
- Shrapnel Sally
- Shum Hoi Ping
- Si Mohammed Nassima
- Siang Ng Yong
- Sibiude Jeanne
- Siddiqui Atif
- Sigfrid Louise
- Sillaots Piret
- Silva Catarina
- Silva Maria Joao
- Silva Rogério
- Sim Lim Heng Benedict
- Sin Wai Ching
- Singh Budha Charan
- Singh Punam
- Sitompul Pompini Agustina
- Sivam Karisha
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Coilin
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Soh Tze Vee
- Solis Monserrat
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet Agnès
- Song Chia Jack
- Song Myung Jin
- Song Rima
- Song Tae
- Sonntagbauer Michael
- Soom Azlan Mat
- Sotto Alberto
- Soum Edouard
- Sousa Uva Maria
- Sousa Ana Chora
- Sousa Marta
- Souza-Dantas Vicente
- Sperry Alexandra
- Spinuzza Elisabetta
- Sri Darshana B. P. Sanka Ruwan
- Sriskandan Shiranee
- Stabler Sarah
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Steinsvik Trude
- Stienstra Ymkje
- Stiksrud Birgitte
- Stolz Eva
- Stone Amy
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Strudwick Samantha
- Stuart Ami
- Stuart David
- Subekti Decy
- Suen Gabriel
- Suen Jacky Y.
- Sukumar Prasanth
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Suppiah Deepashankari
- Surovcová Magdalena
- Suwarti Suwarti
- Svistunov Andrey A.
- Syahrin Sarah
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Sánchez Choez Xavier
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taib Shahdattul Mawarni
- Talarek Ewa
- Taleb Sara
- Talsma Jelmer
- Tampubolon Maria Lawrensia
- Tan Kim Keat
- Tan Le Van
- Tan Yan Chyi
- Tanaka Clarice
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Tanveer Hussain
- Taqdees Huda
- Taqi Arshad
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari
- Tawfik Hassan
- Tedder Richard S.
- Tee Tze Yuan
- Teixeira João
- Tejada Sofia
- Tellier Marie-Capucine
- Teoh Sze Kye
- Teotonio Vanessa
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
- Thabit Alif Adlan Mohd
- Tham Zhang Duan
- Thangavelu Suvintheran
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thirumanickam Jananee
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thurai Surain Raaj Thanga
- Thuy Duong Bich
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tissot Noémie
- Toh Jordan Zhien Yang
- Toki Maria
- Tolppa Timo
- Tonby Kristian
- Tonnii Sia Loong
- Torres Santos-Olmo Rosario Maria
- Torres Antoni
- Torres Margarida
- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Traynor Damien
- Treoux Théo
- Trieu Huynh Trung
- Tripathy Swagata
- Tromeur C. cile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turmel Jean-Marie
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Umer Zubair
- Uribe Alberto
- Usman Asad
- Vajdovics Cristinava
- Val-Flores Luís
- Valle Ana Luiza
- Valran Amélie
- van de Velde Stijn
- van den Berge Marcel
- van der Feltz Machteld
- van der Valk Paul
- van der Vekens Nicky
- van der Voort Peter
- van der Werf Sylvie
- van Dyk Marlice
- van Gulik Laura
- van Hattem Jarne
- van Lelyveld Steven
- van Netten Carolien
- van Twillert Gitte
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasudayan Shoban Raj
- Vauchy Charline
- Vaughan Helen
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira C. sar
- Vijayan Deepak
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Vinh Chau Nguyen Van
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Wan Muhd Shukeri Wan Fadzlina
- Wang Chih-Hsien
- Webb Steven Anthony
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wing Yiu Ng
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xuan Kuan Pei
- Xynogalas Ioannis
- Yacoub Sophie
- Yakop Siti Rohani Binti Mohd
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yee Liang Hing Nicholas
- Yelnik C. cile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zaidan Nor Zaila Binti
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zawadka Konrad
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/12/2021
- Field of study
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasiyah Rashan 9
- Aasmine Kaur
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abi Beane 10
- Abid Khatak
- Abigail Beane
- Adam Ali
- Adam Betz
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Cucino
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Martinelli
- Alessandra Notari
- Alex Browne
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Alfredo Antonio Chetta
- Ali Abbas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Alistair Nichol
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amanda Rojek 5
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amiel A Dror
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Aroca
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Luiza Valle
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anais Rampello
- Anand Thakur
- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Benteson Nygaard
- Anders Tveita
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Dias
- Andrea Kelly
- Andrea Rossanese
- Andrea Ticinesi
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Dagens
- Andrew Dagens 5
- Andrew Hershey
- Andrew Law
- Andrew Letizia
- Andrew Udy
- Andrey A Svistunov
- Andriy Bal
- André Cabie
- André Dias
- André Roberto
- Andrés Orquera
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Ankana Satya
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B Docherty
- Annmarie O Callaghan
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ho
- Antonia Ricchiuto
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- António Mesquita
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez-Trujillo
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Arne Søraas
- Arsalan Rahutullah
- Arshad Taqi
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asami Ito
- Asfia Sultana
- Asgar Rishu
- Ashraf Sheharyar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Audrey Dubot-Pérès
- Aurelius Bonfasius
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Ayodhia Pitaloka
- Azlan Mat Soom
- B P Sanka Ruwan Sri Darshana
- Bailey Cassandra
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barbara Wanjiru Citarella
- Barbara Wanjiru Citarella 5
- Basanta Gauli
- Basri Mat Nor
- Bato Hammarström
- Beathe Kiland Granerud
- Beatrice Alex
- Beatriz Amorim Beltrão
- Ben Morton
- Benedict Sim Lim Heng
- Benigno Ferreira
- Benjamin Bach
- Benjamin Lefevre
- Benjamin Smood
- Benjamine Sarton
- Benoit Visseaux
- Benoît Roze
- Benoît Thill
- Bernard Cholley
- Bernardo Neves
- Bernhard Roessler
- Bertrand Dussol
- Bharath Kumar Tirupakuzhi Vijayaraghavan
- Bianca Boxma
- Bianca DeBenedictis
- Biing Horng Lee
- Birgitte Stiksrud
- Blake Mergler
- Blandine Rammaert
- Bouchra Loufti
- Bountoy Sibounheuang
- Brenda Molloy
- Brenda Reeve
- Brian Marsh
- Brigid Flynn
- Brigitte Elharrar
- Briseida Parra
- Bronner P Gonçalves
- Bronner P Gonçalves 5
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bruno Sarmento Banheiro
- Bryan Whelan
- Budha Charan Singh
- Bénédicte Lefebvre
- Bénédicte Rossignol
- Caitriona Cody
- Calvin Wong
- Cameron J Fairfield
- Camile Bouisse
- Camilla Lund Søraas
- Camille Couffignal
- Caren Friedrich
- Carine Roy
- Carla Eira
- Carlo Ferrari
- Carlo Giaquinto
- Carlos Alexandre Antunes de Brito
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- Thomas Perpoint
- Thomas Staudinger
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- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tiziana Meschi
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Touxiong Yiaye
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valeria Balan 5
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
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- Victoria McEneany
- Victoria Shaw
- Vieri Parrini
- Viladeth Praphasiri
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Volkan Korten
- Véronique Lemee
- Víctor Quirós González
- Waasila Jassat
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Xavier Sánchez Choez
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yanay Gorelik
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yuli V Fuentes 1
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases of prospectively collected clinical data on people hospitalized with COVID-19. This dataset was compiled during the COVID-19 pandemic by a network of hospitals that collect data using the ISARIC-World Health Organization Clinical Characterization Protocol and data tools. The database includes data from more than 705,000 patients, collected in more than 60 countries and 1,500 centres worldwide. Patient data are available from acute hospital admissions with COVID-19 and outpatient follow-ups. The data include signs and symptoms, pre-existing comorbidities, vital signs, chronic and acute treatments, complications, dates of hospitalization and discharge, mortality, viral strains, vaccination status, and other data. Here, we present the dataset characteristics, explain its architecture and how to gain access, and provide tools to facilitate its use
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
- Author
- A M Udara Lakshan Attanyake
- Aasiyah Rashan
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abid Khatak
- Adam Ali
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Aftab Imtiaz
- Agamemnon Bakakos
- Agnieszka Oldakowska
- Agnès Meybeck
- Agnès Sommet
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M Meynert
- Allegra Chatterjee
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- Amanda Corley
- Amanda Palacios
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
- Amin Khawaja
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amy Hackmann
- Amy Lester-Grant
- Amy Stone
- Amélie Valran
- Ana Catarino
- Ana Chora Sousa
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Isabel de Pinho Oliveira
- Ana L Rios
- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anand Thakur
- Anant Kataria
- Anatoliy Gavrylov
- Anders Benjamin Kildal
- Anders Tveita
- Andra-Maris Post
- Andre Real
- Andrea Angheben
- Andrea Cortegiani
- Andrea Dell'Amore
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Acker
- Andrew Hershey
- Andrew Udy
- Andrey Svistunov
- Andriy Bal
- André Cabie
- André Dias
- André Roberto
- Andy Dong
- Andy Law
- Aneela Altaf
- Angel Asensio
- Angel Sanchez-Miralles
- Angela Alberti
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Ankana Satya
- Anna Beltrame
- Anna Ciullo
- Anna Greti Everding
- Anna Jung
- Anne Conrad
- Anne Guillaumot
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne Opavsky
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B Docherty
- Annmarie O Callaghan
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Anton Prinssen
- Antoni Torres
- Antonia Ricchiuto
- Antonio Arcadipane
- Antonio Lalueza
- Antonio Loforte
- Antonio Pesenti
- António Mesquita
- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez-Trujillo
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Arsalan Rahutullah
- Arshad Taqi
- Arsène Kpangon
- Arthur Garan
- Ary Serpa Neto
- Asad Usman
- Asfia Sultana
- Asgar Rishu
- Ashraf Sheharyar
- Asim Rana
- Asma Moin
- Astarini Hidayah
- Atif Siddiqui
- Attaur Rehman
- Audrey Barrelet
- Aurelius Bonfasius
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Ayodhia Pitaloka
- Azlan Mat Soom
- B P Sanka Ruwan Sri Darshana
- Bailey Cassandra
- Baillie J Kenneth
- Bairbre McNicholas
- Bambang Pujo Semedi
- Barrio Noelia García
- Baruch Joaquín
- Basanta Gauli
- Basri Mat Nor
- Beane Abigail
- Beathe Kiland Granerud
- Beatrice Alex
- Beatriz Amorim Beltrão
- Benigno Ferreira
- Benjamin Bach
- Benjamin Lefevre
- Benjamin Smood
- Benjamine Sarton
- Benoit Visseaux
- Benoît Roze
- Benoît Thill
- Bernard Cholley
- Bernhard Roessler
- Bertrand Dussol
- Bianca Boxma
- Biing Horng Lee
- Birgitte Stiksrud
- Blake Mergler
- Blandine Rammaert
- Blumberg Lucille
- Bouchra Loufti
- Bozza Fernando
- Brenda Molloy
- Brenda Reeve
- Brendan Scicluna
- Brian Marsh
- Brigitte Elharrar
- Briseida Parra
- Broadley Tessa
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bruno Sarmento Banheiro
- Bryan Whelan
- Budha Charan Singh
- Burrell Aidan
- Bénédicte Lefebvre
- Bénédicte Rossignol
- Caitriona Cody
- Calvin Wong
- Cameron J Fairfield
- Camile Bouisse
- Camille Couffignal
- Caren Friedrich
- Carine Roy
- Carla Eira
- Carlos Alexandre Antunes de Brito
- Carlos Lumbreras Bermejo
- Carlos M Luna
- Carlos Pimentel
- Carmen Infante Dominguez
- Carola Pierobon
- Carolien van Netten
- Caroline Kosgei
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- Caroline Mudara
- Caroline Semaille
- Carolline Araujo
- Carrol Gamble
- Carson Gail
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- Cynthia Alegre
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- Cyril Le Bris
- Cécile Goujard
- Cécile Mear-Passard
- Cécile Tromeur
- Cécile Yelnik
- Cédric Joseph
- Cédric Laouénan
- Céline Dorival
- Céline Ficko
- Céline Michelanglei
- César Vieira
- Dafsah Juzar
- Dag Henrik Reikvam
- Dagens Andrew
- Daisuke Kasugai
- Dalia Lopez-Colon
- Damien Bouhour
- Dan Meyer
- Daniel Glikman
- Daniel Haber
- Daniel Ivulich
- Daniel Marino
- Daniel Mathieu
- Daniel Perez
- Daniela Guerreiro
- Danielle Jaafar
- Danilo Buonsenso
- Dankwa Emmanuelle A
- Darakhshan Kanwal
- Dario Sinatti
- Darren Dahly
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- Dinesh Kuriakose
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- Dorothea Rosenberger
- Dorothy Breen
- Dounia Bouhmani
- Douwe F Postma
- Drashti Patel
- Dubravka Supic
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- Ebenezer Rabindrarajan
- Edel Meaney
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- Edouard Soum
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- Efstathia Mihelis
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- Egle Saviciute
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- Eka Airlangga
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- Tae Song
- Taha Pasha
- Tahira Jamal Mohamed
- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Tala Al-Dabbous
- Tamara Seitz
- Tan Pei Wen
- Tarek Elshazly
- Tatiana Fonseca
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tjard Schermer
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Vadim Tieroshyn
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vecham Pavan Kumar
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Janes
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Véronique Lemee
- Víctor Quirós González
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wei Jia
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wils Evert-Jan
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 28/02/2023
- Field of study
Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients. Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV). Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%. Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death