299 research outputs found
高効率周辺修飾法を用いた新規機能性ポルフィリンの開発
京都大学0048新制・課程博士博士(理学)甲第20946号理博第4398号新制||理||1632(附属図書館)京都大学大学院理学研究科化学専攻(主査)教授 大須賀 篤弘, 教授 依光 英樹, 教授 丸岡 啓二学位規則第4条第1項該当Doctor of ScienceKyoto UniversityDGA
Synthesis and catalytic activities of porphyrin-based PCP pincer complexes.
2, 18-Bis(diphenylphosphino)porphyrins undergo peripheral cyclometalation with group 10 transition-metal salts to afford the corresponding porphyrin-based PCP pincer complexes. The porphyrinic plane and the PCP-pincer unit are apparently coplanar, with small strain. The catalytic activities of the porphyrin-based pincer complexes at the periphery were investigated in the allylation of benzaldehyde with allylstannane and in the 1, 4-reduction of chalcone to discover the electronic interplay between the inner metal and the outer metal in catalysis
Numerical Simulations of Axisymmetric Flows in Astrophysics and their Visualization by a Video Movie
Numerical simulations of axisymmetric flow in four different astrophysical situations are performed, and their results are visualized by using a video movie. The situations considered are : 1) an accretion flow on to a gravitating compact object allowing maximum accrection ; 2) a jet formation in a flow past a gravitating rigid sphere ; 3) an interaction between a supersonic wind from a central object and a uniform supersonic incident flow ; 4) a wind bubble formed by spherical supersonic wind. The video tape of VHS/NTSC format is available from the author
Deep learning-based image deconstruction method with maintained saliency
人間の視覚注意解析のための人工知能(AI)技術の開発に成功. 京都大学プレスリリース. 2022-09-29.Visual properties that primarily attract bottom-up attention are collectively referred to as saliency. In this study, to understand the neural activity involved in top-down and bottom-up visual attention, we aim to prepare pairs of natural and unnatural images with common saliency. For this purpose, we propose an image transformation method based on deep neural networks that can generate new images while maintaining the consistent feature map, in particular the saliency map. This is an ill-posed problem because the transformation from an image to its corresponding feature map could be many-to-one, and in our particular case, the various images would share the same saliency map. Although stochastic image generation has the potential to solve such ill-posed problems, the most existing methods focus on adding diversity of the overall style/touch information while maintaining the naturalness of the generated images. To this end, we developed a new image transformation method that incorporates higher-dimensional latent variables so that the generated images appear unnatural with less context information but retain a high diversity of local image structures. Although such high-dimensional latent spaces are prone to collapse, we proposed a new regularization based on Kullback–Leibler divergence to avoid collapsing the latent distribution. We also conducted human experiments using our newly prepared natural and corresponding unnatural images to measure overt eye movements and functional magnetic resonance imaging, and found that those images induced distinctive neural activities related to top-down and bottom-up attentional processing
Selective recognition and electrochemical sensing of dopamine using a ferrocene-based heteroditopic receptor
高齢者における睡眠の質と夜間頻尿関連 : 在宅脳波データを用いた地域密着研究
PURPOSE: We objectively investigated the relationship between sleep quality/efficiency and factors associated with micturition using at-home electroencephalogram assessment. MATERIALS AND METHODS: Participants were recruited from among those enrolled in the Fujiwara-kyo Study, a community based longitudinal evaluation that began in Nara Prefecture, Japan, in 2007. Included participants were men at least 65 years old who woke up in the middle of the night/early morning at least 3 times per week with the urge to void. We evaluated lower urinary tract symptoms using the I-PSS and subjective sleep quality using the Pittsburgh Sleep Quality Index. Uroflowmetry and 3-day frequency volume charting measurements were also obtained. Electroencephalogram recordings were obtained during sleep to evaluate objective sleep quality. RESULTS: Final analysis included data from 47 participants. I-PSS-quality of life score and slow wave sleep time were independent predictors of good subjective sleep quality as determined by Pittsburgh Sleep Quality Index scores. Nocturnal urinary volume was an independent predictor of greater sleep efficiency. Maximum flow rate was an independent predictor of longer slow wave sleep time. CONCLUSIONS: In elderly men with nocturia, sleep quality is associated with lower urinary tract function. Higher subjective sleep quality is associated with longer slow wave sleep time and less severe lower urinary tract symptoms. Higher objective sleep quality is further associated with a higher urinary flow rate and lower nocturnal urinary volume.博士(医学)・甲第669号・平成29年3月15日Copyright © 2017 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved
臥床早期の下肢水分移行はHUSを減少させる
OBJECTIVE: To investigate whether or not the leg fluid displacement observed when moving from the standing to recumbent position at bedtime reduces the hours of undisturbed sleep (HUS). METHODS: Men aged 50 years or older who were hospitalized for urological diseases were investigated. Body water evaluation was performed three times with a bioelectric impedance method: (i) 17:00, (ii) 30 min after (short-term), and (iii) waking up (long-term). A frequency volume chart was used to evaluate the status of nocturnal urine production, and the factors affecting HUS were investigated. RESULTS: A total of 50 patients (mean age: 68 years) were enrolled. Short-term changes in extracellular fluid (ECF in the legs showed a significant positive correlation with urine production per unit of time at the first nocturnal voiding (UFN/HUS) (r = 0.45, P = 0.01). In the comparison between patients who had <3 HUS vs. those who had ≥3 HUS, the <3 HUS group showed significantly greater short-term changes in leg fluid volume, night-time water intake (17:00-06:00), and UFN/HUS. Multivariate analysis to assess the risk factors for <3 HUS indicated UFN/HUS as a risk factor in the overall model, and short-term changes in leg ECF and night-time water intake as risk factors in the model that only considered factors before sleep. CONCLUSIONS: Nocturnal leg fluid displacement may increase urine production leading up to first voiding after going to bed, and consequently, induce early awakening after falling asleep.博士(医学)・甲第703号・平成31年3月15日© 2017 John Wiley & Sons Australia, LtdThis is the pre-peer reviewed version of the following article: [https://onlinelibrary.wiley.com/doi/10.1111/luts.12176], which has been published in final form at [http://dx.doi.org/10.1111/luts.12176]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
A Fast Runtime Visualization of a GPU-Based 3D-FDTD Electromagnetic Simulation
In this paper, we present design and implementation of a fast runtime visualizer for a GPU-based 3D-FDTD electromagnetic simulation. We focus on improving the productivity of simulator development without compromising simulation performance. In order to keep the portability, we implemented a visualizer with the MVC model, where simulation kernels and visualization process were completely separated. For high-speed visualization, an interoperability mechanism between OpenGL and CUDA was used in addition to efficient utilization of programmable shaders. We also propose an asynchronous multi-threaded execution with a triple-buffering technique so that developers can concentrate on developing their simulation kernels. As a result of empirical visualization experiments of electromagnetic simulations for practical antenna design, it was revealed that our implementation achieved a rendering throughput of 90 FPS for a view port of 512 x 512 pixels, which corresponds to a 12.9 times speedup compared to when the OpenGL-CUDA interoperability mechanism was not utilized. When a standard visualization throughput of 60 FPS was selected, the performance overhead imposed by the visualization process was 15.8%, which was reasonably low compared to a speedup of the simulation kernel gained by the GPU acceleration
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