Grappling with the gods: Reflections for coaches of the narcissistic leader

While the general research literature has addressed narcissistic behaviours in executive leaders, the effect of its presence on the success of the executive coaching process has not been explored. The predominance of narcissism in our executives, however, has been established--making it likely that coaches will deal with these types of behavioural tendencies. Drawing from interviews, an organizational survey and observations at a single organizational site, as well as broader coaching experiences, this article offers a practical reflection of narcissism in the organizational environment and presents core issues that coaches may face. It also suggests some possible guidelines for coaching this type of client and considers how much we as coaches should endeavor to assist our clients in changing this aspect of themselves

Protocol for a randomised controlled trial of subacromial spacers for tears affecting rotator cuff tendons : a randomised, efficient, adaptive clinical trial in surgery (START:REACTS)

Introduction: Shoulder pain due to irreparable rotator cuff tears can cause substantial disability, but treatment options are limited. A balloon spacer is a relatively simple addition to a standard arthroscopic debridement procedure, but it is costly and there is no current randomised trial evidence to support its use. This trial will evaluate the clinical and cost-effectiveness of a subacromial balloon spacer for individuals undergoing arthroscopic debridement for irreparable rotator cuff tears. New surgical procedures can provide substantial benefit to patients. Good quality randomised controlled trials (RCTs) are needed, but trials in surgery are typically long and expensive, exposing patients to risk and the healthcare system to substantial costs. One way to improve the efficiency of trials is with an adaptive sample size. Such methods are well established in drug trials but have rarely, if ever, been used in surgical trials. Methods and analysis: Subacromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery (START:REACTS) is a participant and assessor blinded, adaptive, multicentre RCT comparing arthroscopic debridement with the InSpace balloon (Stryker, USA) to arthroscopic debridement alone for people with a symptomatic irreparable rotator cuff tear. It uses a group sequential adaptive design where interim analyses are performed using all of the 3, 6 and 12-month data that are available at each time point. A maximum of 221 participants will be randomised (1:1 ratio), this will provide 90% power (at the 5% level) for a 6 point difference in the primary outcome; the Oxford Shoulder Score at 12 months. A substudy will use deltoid-active MRI scans in 56 participants to assess the function of the balloon. Analysis will be on an intention-to-treat basis and reported according to principles established in the Consolidated Standards of Reporting Trials statement. Ethics and dissemination: NRES number 18/WM/0025. The results will be disseminated via peer-reviewed publications, presentations at conferences, lay summaries and social media. Trial registration number: ISRCTN1782559

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

“If ever there was someone to keep me at home”: Theorizing screen representations of siblinghood through a case study of Into the Wild (2007)

This is an Accepted Manuscript of an article published by Taylor & Francis in Quarterly Review of Film and Video on 04/03/2021, available online: https://doi.org/10.1080/10509208.2021.1886823Images of siblings pervade the screen, yet their representation remains under-explored. Though sibling relationships are common, these lateral bonds are often overlooked in favor of the vertical bonds privileged by Freudian psychoanalysis. Into the Wild (dir. Sean Penn 2007), though ostensibly focused on the solitary journey of its protagonist, Chris McCandless, can be read as a narrative of siblinghood and here serves as a case study for exploring ways of theorizing the sibling relationship on screen. Often, there is an inherent anxiety embedded within representations of close adult bonds between brothers and sisters, resulting in frequent on-screen separation. Though Chris and his sister Carine are similarly separated for the majority of the film, their relationship is foregrounded by framing Chris’s story through Carine’s re-telling. Here, the sibling pair may be better understood through the prism of modern discourses of the soulmate, emphasizing the value of knowledge to the sibling relationship and looking beyond the vertical to consider how lateral bonds might be excavated from the edges of the screen