Court of Public Opinion in and for the State of Uncertainty

Our session has two goals. First, we aim to stimulate debate over a ubiquitous, yet largely unchallenged, instrument that purports to operationalize Jungian personality theory (the Myers-Briggs Type Indicator). Second, we suggest a platform for teaching management theories, the mock-trial, which manifests active learning as well as critical thinking and has been successfully utilized in other disciplines. With contributors playing key roles in the trial and volunteers from the audience serving as potential prosecution and defense witnesses as well as the jury, we hope the discourse on substantive theory and teaching process will provide the jolt OBTC 2008 envisions

On the interaction of morphology and syntax

Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 1980.MICROFICHE COPY AVAILABLE IN ARCHIVES AND HUMANITIES.Vita.Bibliography: leaves 218-223.by Ann Kathleen Farmer.Ph.D

A Spatial View of How United States Cesarean Section Rates Changed from 1990-2014

The overuse of cesarean sections (c-sections) in the United States is a contested issue. The rate of c-section births in 2015 at 32% was over double the World Health Organization recommendation of 10-15%. We employed spatial statistical methods and data visualization techniques to assess the temporal and spatial trends in c-section rates by county across the US. While the national rate of c-section remained stable at the beginning and end of this study period, an increase in rates from 1997 to 2009 was reflected simultaneously in national, state, and individual county rates. Local indicators of spatial dependence did not show spatial clustering as being connected to, or driving, the change, yet the visualization methods used here show details on individual county deviance from local temporal trends. By highlighting counties which do not follow the trends of their neighbors, we identify exceptional locations which could help further the study of the determinants of changing c-section rates in the United States.</p

Recent advances in the application of stable isotope ratio analysis in forensic chemistry

This review paper updates the previous literature in relation to the continued and developing use of stable isotope ratio analysis in samples which are relevant to forensic science. Recent advances in the analysis of drug samples, explosive materials, and samples derived from human and animal samples are discussed. The paper also aims to put the use of isotope ratio mass spectrometry into a forensic context and discuss its evidential potential

The Citizen Nurse: An Educational Innovation for Change

Background: Nursing education needs to provide the necessary tools for students to develop leadership skills and to practice civic agency to create meaningful change in the shifting health care field. This article focuses on facilitating a student\u27s role in becoming a citizen nurse through curricular modifications. Method: Through an ongoing partnership, nursing faculty and community organizers implemented a year-long pilot project to discover the deeper insights into the role of a citizen nurse and to analyze the skills students need to be effective agents of change. Pilot lectures and workshops were held throughout the academic year, and curricular changes were implemented. Results: Based on input from pilot class experiences, student reflections, and faculty workshop feedback, the decision to implement ongoing curricular changes was made by the department. Conclusion: The development of citizen nurses in nursing education will pave the way for praxis embedded in meaningful work with just solutions, enhancing the agency of all involved in promoting health and well-being. [J Nurs Educ. 2017;56(4):247–250.

Detection and Preservation of Biosignatures in Mars Analogs Hot Spring Deposits from the Taupo Volcanic Zone, New Zealand

Characterizing the preservation potential of biosignatures in martian analogs is essential in the quest for biosignatures with martian rovers. Hot spring silica deposits are part of the minerals with a high preservation potential. As part of an ongoing study, we are characterizing the nature and distribution of organic molecules including lipid biomarkers in a range of analog hot spring deposits, evaluating their preservation potential, and determining the potential signals from flight-like experiments. We are focusing on various geothermal fields in the New Zealand Taupo Volcanic Zone with physical and chemical variabilities. Samples are being extracted for lipid biomarker characterization as well as analysis using flight-like experiments from the current and future pyrolyzer-gas chromatographmass spectrometer instruments SAM and MOMA on the Curiosity and Exomars2020 rovers. The aim of work is to improve our knowledge of the detection and preservation of biosignatures in different hot spring lithologies while simultaneously evaluating the potential limits and biases of flight experiments.Fil: Millan, Maëva. University Of Georgetown; Estados Unidos. National Aeronautics and Space Administration; Estados UnidosFil: Campbell, Kathleen A.. Universidad Nacional y Kapodistriaca de Atenas; GreciaFil: Van Kranendonk, Martin J.. University of New South Wales; AustraliaFil: Sriaporn, Chanenath. Universidad Nacional y Kapodistriaca de Atenas; GreciaFil: Handley, Kim M.. Universidad Nacional y Kapodistriaca de Atenas; GreciaFil: Dobson, Michaela. Universidad Nacional y Kapodistriaca de Atenas; GreciaFil: Camp, Sîan. Universidad Nacional y Kapodistriaca de Atenas; GreciaFil: Teece, Bonnie. University of New South Wales; AustraliaFil: Guido, Diego Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Instituto de Recursos Minerales. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto de Recursos Minerales; ArgentinaFil: Djokic, Tara. University of New South Wales; AustraliaFil: Farmer, Jack D.. Arizona State University; Estados UnidosFil: Stewart Johnson, Sarah. University Of Georgetown; Estados UnidosEPSC-DPS Joint Meeting 2019GenevaSuizaEuropean Process Safety Centr

PCR versus Hybridization for Detecting Virulence Genes of Enterohemorrhagic Escherichia coli

We compared PCR amplification of 9 enterohemorrhagic Escherichia coli virulence factors among 40 isolates (21 O/H antigenicity classes) with DNA hybridization. Both methods showed 100% of the chromosomal and phage genes: eae, stx, and stx2. PCR did not detect 4%–20% of hybridizable plasmid genes: hlyA, katP, espP, toxB, open reading frame (ORF) 1, and ORF2

Heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes

A systems biology–based analysis shows that differentiating adipocytes look very different at the single-cell level and form distinct cellular subpopulations

Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets

Common variable immunodeficiency (CVID) is increasingly recognized for its association with autoimmune and inflammatory complications. Despite recent advances in immunophenotypic and genetic discovery, clinical care of CVID remains limited by our inability to accurately model risk for non-infectious disease development. Herein, we demonstrate the utility of unbiased network clustering as a novel method to analyze inter-relationships between non-infectious disease outcomes in CVID using databases at the United States Immunodeficiency Network (USIDNET), the centralized immunodeficiency registry of the United States, and Partners, a tertiary care network in Boston, MA, USA, with a shared electronic medical record amenable to natural language processing. Immunophenotypes were comparable in terms of native antibody deficiencies, low titer response to pneumococcus, and B cell maturation arrest. However, recorded non-infectious disease outcomes were more substantial in the Partners cohort across the spectrum of lymphoproliferation, cytopenias, autoimmunity, atopy, and malignancy. Using unbiased network clustering to analyze 34 non-infectious disease outcomes in the Partners cohort, we further identified unique patterns of lymphoproliferative (two clusters), autoimmune (two clusters), and atopic (one cluster) disease that were defined as CVID non-infectious endotypes according to discrete and non-overlapping immunophenotypes. Markers were both previously described {high serum IgE in the atopic cluster [odds ratio (OR) 6.5] and low class-switched memory B cells in the total lymphoproliferative cluster (OR 9.2)} and novel [low serum C3 in the total lymphoproliferative cluster (OR 5.1)]. Mortality risk in the Partners cohort was significantly associated with individual non-infectious disease outcomes as well as lymphoproliferative cluster 2, specifically (OR 5.9). In contrast, unbiased network clustering failed to associate known comorbidities in the adult USIDNET cohort. Together, these data suggest that unbiased network clustering can be used in CVID to redefine non-infectious disease inter-relationships; however, applicability may be limited to datasets well annotated through mechanisms such as natural language processing. The lymphoproliferative, autoimmune, and atopic Partners CVID endotypes herein described can be used moving forward to streamline genetic and biomarker discovery and to facilitate early screening and intervention in CVID patients at highest risk for autoimmune and inflammatory progression

The link between volcanism and plutonism in epizonal magma systems; high-precision U–Pb zircon geochronology from the Organ Mountains caldera and batholith, New Mexico

The Organ Mountains caldera and batholith expose the volcanic and epizonal plutonic record of an Eocene caldera complex. The caldera and batholith are well exposed, and extensive previous mapping and geochemical analyses have suggested a clear link between the volcanic and plutonic sections, making this an ideal location to study magmatic processes associated with caldera volcanism. Here we present high-precision thermal ionization mass spectrometry U–Pb zircon dates from throughout the caldera and batholith, and use these dates to test and improve existing petrogenetic models. The new dates indicate that Eocene volcanic and plutonic rocks in the Organ Mountains formed from ~44 to 34 Ma. The three largest caldera-related tuff units yielded weighted mean [superscript 206]Pb/[superscript 238]U dates of 36.441 ± 0.020 Ma (Cueva Tuff), 36.259 ± 0.016 Ma (Achenback Park tuff), and 36.215 ± 0.016 Ma (Squaw Mountain tuff). An alkali feldspar granite, which is chemically similar to the erupted tuffs, yielded a synchronous weighted mean [superscript 206]Pb/[superscript 238]U date of 36.259 ± 0.021 Ma. Weighted mean [superscript 206]Pb/[superscript 238]U dates from the larger volume syenitic phase of the underlying Organ Needle pluton range from 36.130 ± 0.031 to 36.071 ± 0.012 Ma, and the youngest sample is 144 ± 20 to 188 ± 20 ka younger than the Squaw Mountain and Achenback Park tuffs, respectively. Younger plutonism in the batholith continued through at least 34.051 ± 0.029 Ma. We propose that the Achenback Park tuff, Squaw Mountain tuff, alkali feldspar granite and Organ Needle pluton formed from a single, long-lived magma chamber/mush zone. Early silicic magmas generated by partial melting of the lower crust rose to form an epizonal magma chamber. Underplating of the resulting mush zone led to partial melting and generation of a high-silica alkali feldspar granite cap, which erupted to form the tuffs. The deeper parts of the chamber underwent continued recharge and crystallization for 144 ± 20 ka after the final eruption. Calculated magmatic fluxes for the Organ Needle pluton range from 0.0006 to 0.0030 km3/year, in agreement with estimates from other well-studied plutons. The petrogenetic evolution proposed here may be common to many small-volume silicic volcanic systems