Effect of aggressive gas on separation properties of carbon molecular sieve hollow fiber membranes

A practical membrane separation process is considered in this study for removal of CO2 from natural gas in the presence of H2S. Carbon molecular sieve (CMS) materials derived from Matrimid® and 6FDA:BPDA-DAM have been used for this particular separation. Optimization of V-treatment for CMS has been done in this study to prevent collapse of the substructure of polymer hollow fibers upon pyrolysis. Most importantly, this treatment was proven that this method is scalable. Details of interaction of H2S with CMS membranes were also clarified in this work and found to be different for CMS starting from different precursors. In addition to the measured changes in transport performance, analytical characterization techniques proved that H2S conditions CMS membranes by chemical interaction. The H2S conditioning led to a permanently reduced permeance through the CMS membrane, thereby making the membrane less attractive for industrial use. To prevent this poisoning, a novel method, called chlorine fixation, for neutralizing the reactive edges of the CMS was explored. The study has benchmarked the performance of CMS membranes in a sour gas feed. This work has established a framework for providing a potentially practical hollow fiber membrane technology for aggressive gas separation.Ph.D

Identifying Purchase Intent from Social Posts

In present times, social forums such as Quora and Yahoo! Answers constitute powerful media through which people discuss on a variety of topics and express their intentions and thoughts. Here they often reveal their potential intent to purchase - 'Purchase Intent' (PI). A purchase intent is defined as a text expression showing a desire to purchase a product or a service in future. Extracting posts having PI from a user's social posts gives huge opportunities towards web personalization, targeted marketing and improving community observing systems. In this paper, we explore the novel problem of detecting PIs from social posts and classifying them. We find that using linguistic features along with statistical features of PI expressions achieves a significant improvement in PI classification over 'bag-of-words' based features used in many present day social-media classification tasks. Our approach takes into consideration the specifics of social posts like limited contextual information, incorrect grammar, language ambiguities, etc. by extracting features at two different levels of text granularity - word and phrase based features and grammatical dependency based features. Apart from these, the patterns observed in PI posts help us to identify some specific features

Health-status outcomes with invasive or conservative care in coronary disease

BACKGROUND In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients. METHODS We assessed angina-related symptoms, function, and quality of life with the Seattle Angina Questionnaire (SAQ) at randomization, at months 1.5, 3, and 6, and every 6 months thereafter in participants who had been randomly assigned to an invasive treatment strategy (2295 participants) or a conservative strategy (2322). Mixed-effects cumulative probability models within a Bayesian framework were used to estimate differences between the treatment groups. The primary outcome of this health-status analysis was the SAQ summary score (scores range from 0 to 100, with higher scores indicating better health status). All analyses were performed in the overall population and according to baseline angina frequency. RESULTS At baseline, 35% of patients reported having no angina in the previous month. SAQ summary scores increased in both treatment groups, with increases at 3, 12, and 36 months that were 4.1 points (95% credible interval, 3.2 to 5.0), 4.2 points (95% credible interval, 3.3 to 5.1), and 2.9 points (95% credible interval, 2.2 to 3.7) higher with the invasive strategy than with the conservative strategy. Differences were larger among participants who had more frequent angina at baseline (8.5 vs. 0.1 points at 3 months and 5.3 vs. 1.2 points at 36 months among participants with daily or weekly angina as compared with no angina). CONCLUSIONS In the overall trial population with moderate or severe ischemia, which included 35% of participants without angina at baseline, patients randomly assigned to the invasive strategy had greater improvement in angina-related health status than those assigned to the conservative strategy. The modest mean differences favoring the invasive strategy in the overall group reflected minimal differences among asymptomatic patients and larger differences among patients who had had angina at baseline

Initial invasive or conservative strategy for stable coronary disease

BACKGROUND Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, 121.8 percentage points; 95% CI, 124.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used