114 research outputs found

    A New Genetic Programming Algorithm for Building Decision Tree

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    AbstractGenetic programming (GP) is a flexible and powerful evolutionary technique with some special features that are suitable for building a classifier of tree representation. However, unsuitable step size of editing operator will destroy the continuity of the evolution. In this paper, we propose a multiage genetic programming (MGP) algorithm to build a classifier on a given training set. Individuals are grouped into different groups according to their ages (tree size). The competitions between individuals are limited in the same groups. That prevents the structure editing operators from destroying the continuity of the evolution. The experimental results showed that the MGP algorithm is superior to the traditional genetic programming algorithm (GP) in building decision tree

    Object Detection in Videos with Tubelet Proposal Networks

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    Object detection in videos has drawn increasing attention recently with the introduction of the large-scale ImageNet VID dataset. Different from object detection in static images, temporal information in videos is vital for object detection. To fully utilize temporal information, state-of-the-art methods are based on spatiotemporal tubelets, which are essentially sequences of associated bounding boxes across time. However, the existing methods have major limitations in generating tubelets in terms of quality and efficiency. Motion-based methods are able to obtain dense tubelets efficiently, but the lengths are generally only several frames, which is not optimal for incorporating long-term temporal information. Appearance-based methods, usually involving generic object tracking, could generate long tubelets, but are usually computationally expensive. In this work, we propose a framework for object detection in videos, which consists of a novel tubelet proposal network to efficiently generate spatiotemporal proposals, and a Long Short-term Memory (LSTM) network that incorporates temporal information from tubelet proposals for achieving high object detection accuracy in videos. Experiments on the large-scale ImageNet VID dataset demonstrate the effectiveness of the proposed framework for object detection in videos.Comment: CVPR 201

    [μ-2,2′-Dimethyl-2,2′-(p-phenyl­ene)diprop­yl]bis­[chloridobis(2-methyl-2-phenyl­prop­yl)tin(IV)]

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    The mol­ecular structure of the title compound, [Sn2(C10H13)4(C14H20)Cl2], is a binuclear centrosymmetric complex, in which the Sn atoms are four-coordinated by three C atoms and one Cl atom in a distorted tetra­hedral geometry

    HIF-1α effects on angiogenic potential in human small cell lung carcinoma

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    <p>Abstract</p> <p>Background</p> <p>Hypoxia-inducible factor-1 alpha (HIF-1α) maybe an important regulatory factor for angiogenesis of small cell lung cancer (SCLC). Our study aimed to investigate the effect of HIF-1α on angiogenic potential of SCLC including two points: One is the effect of HIF-1α on the angiogenesis of SCLC <it>in vivo</it>. The other is the regulation of angiogenic genes by HIF-1α <it>in vitro </it>and <it>in vivo</it>.</p> <p>Methods</p> <p><it>In vivo </it>we used an alternative method to study the effect of HIF-1a on angiogenic potential of SCLC by buliding NCI-H446 cell transplantation tumor on the chick embryo chorioallantoic membrane (CAM) surface. <it>In vitro </it>we used microarray to screen out the angiogenic genes regulated by HIF-1a and tested their expression level in CAM transplantation tumor by RT-PCR and Western-blot analysis.</p> <p>Results</p> <p><it>In vivo </it>angiogenic response surrounding the SCLC transplantation tumors in chick embryo chorioallantoic membrane (CAM) was promoted after exogenous HIF-1α transduction (p < 0.05). <it>In vitro </it>the changes of angiogenic genes expression induced by HIF-1α in NCI-H446 cells were analyzed by cDNA microarray experiments. HIF-1α upregulated the expression of angiogenic genes VEGF-A, TNFAIP6, PDGFC, FN1, MMP28, MMP14 to 6.76-, 6.69-, 2.26-, 2.31-, 4.39-, 2.97- fold respectively and glycolytic genes GLUT1, GLUT2 to2.98-, 3.74- fold respectively. In addition, the expression of these angiogenic factors were also upregulated by HIF-1α in the transplantion tumors in CAM as RT-PCR and Western-blot analysis indicated.</p> <p>Conclusions</p> <p>These results indicated that HIF-1α may enhance the angiogenic potential of SCLC by regulating some angiogenic genes such as VEGF-A, MMP28 etc. Therefore, HIF-1α may be a potential target for the gene targeted therapy of SCLC.</p

    Terahertz Sensor via Ultralow-Loss Dispersion-Flattened Polymer Optical Fiber: Design and Analysis

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    A novel cyclic olefin copolymer (COC)-based polymer optical fiber (POF) with a rectangular porous core is designed for terahertz (THz) sensing by the finite element method. The numerical simulations showed an ultrahigh relative sensitivity of 89.73% of the x-polarization mode at a frequency of 1.2 THz and under optimum design conditions. In addition to this, they showed an ultralow confinement loss of 2.18 × 10−12 cm−1, a high birefringence of 1.91 × 10−3, a numerical aperture of 0.33, and an effective mode area of 1.65 × 105 μm2 was obtained for optimum design conditions. Moreover, the range dispersion variation was within 0.7 ± 0.41 ps/THz/cm, with the frequency range of 1.0–1.4 THz. Compared with the traditional sensor, the late-model sensor will have application value in THz sensing and communication

    Design and optimization of dispersion-flattened microarray-core fiber with ultralow loss for terahertz transmission

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    The paper establishes a late-model of microarray-core based polymer optical fiber with flattened dispersion and ultra-low losses. Its transmission properties are calculated by virtue of the beam propagation approach. From the simulation results, it finds that the modelled fiber has a near-zero dispersion property of 0.29 ± 0.16 ps/THz/cm in a frequency area of 1.05 THz to 1.78 THz, a high birefringence of 1.6 × 10-3, an ultra-low confinement loss of 3.78 × 10-10 dB/m, an effective mode field zone of 4.6 × 105 μm2, and a nonlinear coefficient of 1.2 km-1·W−1. With these good properties, the modelled fiber could be applied for ethanol detection and polarization maintaining THz applications

    Vitamin D status in tuberculosis patients with diabetes, prediabetes and normal blood glucose in China: a cross-sectional study.

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    OBJECTIVE: The association between tuberculosis (TB), diabetes mellitus (DM) and vitamin D status is poorly characterised. We therefore: (1) determined vitamin D status in patients with TB in relation to whether they had normal fasting blood glucose (FBG), pre-DM or DM and (2) assessed whether baseline characteristics in patients with TB, including their DM status, were associated with vitamin D deficiency. METHODS: In patients with TB consecutively attending six clinics or hospitals in China, we measured 25-hydroxycholecalciferol (25-(OH)D3) at the time of registration using electrochemiluminescence in a COBASE 601 Roche analyser by chemiluminescence immunoassay. Data analysis was performed using the χ2 test, ORs and multivariate logistic regression. RESULTS: There were 306 eligible patients with TB, including 96 with smear positive pulmonary TB, 187 with smear negative pulmonary TB and 23 with extrapulmonary TB. Of these, 95 (31%) had normal blood glucose, 83 (27%) had pre-DM and 128 (42%) had DM. Median serum vitamin D levels were 16.1 ng/mL in patients with TB with normal FBG, 12.6 ng/mL in patients with TB with pre-DM and 12.1 ng/mL in patients with TB with DM (p<0.001). The study highlighted certain baseline characteristics associated with vitamin D deficiency (25-(OH)D3<20 ng/mL). After adjusting for confounders, serum vitamin D deficiency was significantly more common in patients being registered in the cold season (November to April) (p=0.006) and in those with DM (p=0.003). CONCLUSION: Vitamin D levels are lower in patients with TB with pre-DM and DM and are also affected by certain baseline characteristics that include being registered in the cold season and having DM. TB programmes need to pay more attention to vitamin D status in their patients, especially if there is coexisting pre-DM or DM
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